Effectiveness of antiemetics in control of antineoplastic chemotherapy-induced emesis at home

• Autor(a) principal: Castro,Marielly Cunha
• Data de Publicação: 2014
• Outros Autores: Araújo,Suely Amorim de, Mendes,Thaís Rezende, Vilarinho,Glauciane Silva, Mendonça,Maria Angélica Oliveira
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Acta Paulista de Enfermagem (Online)
• Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-21002014000500005
• topic: Vomiting/chemically induced; Chemotherapy; Antinoeplastics agents/adverse effects; Antiemetics; Oncology nursing; Residential treatment

Objective Evaluating if antiemetics are effective in the prevention or treatment at home, of chemotherapy-induced emesis. Methods In total, were included 42 women with breast cancer in moderately emetogenic chemotherapy, using dexamethasone/ondansetron before each cycle. The frequency of nausea and vomiting was obtained by applying the instrument in the pre-chemotherapy period, and 24h, 48h, 72h and 96h after chemotherapy. The use of antiemetics was considered in accordance with adherence to medical prescription. Results All patients (n = 42, 100%) reported emesis at some point. Only five cases (11.9%) were anticipatory. In the first 24 hours (acute emesis), 38 (90.5%)ayed), emesis was reported by all despite the regular use (n = 20, 47.6%) or not (n = 22, 52.4%) of antiemetics (ondansetron, dexamethasone and metoclopramide/or dimenhydrinate). Conclusion Antiemetics were not effective in the prevention or treatment at home, of chemotherapy-induced emesis.