People living with HIV on ART have accurate perception of lipodystrophy signs: a cross‑sectional study
Autor(a) principal: | |
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Data de Publicação: | 2017 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Universitário da Ânima (RUNA) |
Texto Completo: | https://repositorio.animaeducacao.com.br/handle/ANIMA/2612 |
Resumo: | BACKGROUND: The prevalence of lipodystrophy ranges from 31 to 65%, depending on the criteria adopted for diagnosis. The usual methods applied in the diagnosis vary from self-perception, medical examination, skinfolds measurements, or even imaging assessment for confirmation of fat distribution changes. Although several methods have been developed, there is no gold standard for characterization of LA and LH, or mixed forms. This study aimed to compare self-reported signs of lipodystrophy with objective measures by skinfolds and circumferences, and to evaluate the prevalence of lipoatrophy (LA) and lipohypertrophy (LH) among subjects living with HIV/AIDS on ART. METHODS: A cross-sectional study enrolled participants living with HIV/AIDS receiving ART, aged 18 years or older from an outpatient health care center, in Southern Brazil. Self-reported body fat enlargement in the abdomen, chest or breasts, and dorsocervical fat pad were used to determine LH, while LA was identified by self-reported fat wasting of the face, neck, legs, arms or buttocks. Measurements were obtained with a scientific caliper for infraorbital, buccal, and submandibular skinfolds, and using an inelastic tape to measure circumferences of waist, hip, neck, and arm. LH and LA were established by the presence of at least one self-reported sign. RESULTS: Comparisons of self-reported signs with objective measurements for men and women were carried out in 815 participants on ART, out of 1240 participants with HIV infection. Self-report of decreased facial fat and sunken cheeks was associated with lower infraorbital, buccal, and submandibular skinfolds. Participants who reported buffalo hump had, on average, greater neck circumference, as well as those who have increased waist circumference also reported abdominal enlargement, but no buttock wasting. Men were most commonly affected by lipoatrophy (73 vs. 53%; P < 0.001), and women by lipohypertrophy (79 vs. 56%; P < 0.001). CONCLUSION: In conclusion, self-reported signs of lipodystrophy and lipoatrophy are prevalent, differ by gender, and are associated with objective measurements in people living with HIV/AIDS. |
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People living with HIV on ART have accurate perception of lipodystrophy signs: a cross‑sectional studyHIVAIDSLipodystrophyLypohypertrophyLipoatrophyBACKGROUND: The prevalence of lipodystrophy ranges from 31 to 65%, depending on the criteria adopted for diagnosis. The usual methods applied in the diagnosis vary from self-perception, medical examination, skinfolds measurements, or even imaging assessment for confirmation of fat distribution changes. Although several methods have been developed, there is no gold standard for characterization of LA and LH, or mixed forms. This study aimed to compare self-reported signs of lipodystrophy with objective measures by skinfolds and circumferences, and to evaluate the prevalence of lipoatrophy (LA) and lipohypertrophy (LH) among subjects living with HIV/AIDS on ART. METHODS: A cross-sectional study enrolled participants living with HIV/AIDS receiving ART, aged 18 years or older from an outpatient health care center, in Southern Brazil. Self-reported body fat enlargement in the abdomen, chest or breasts, and dorsocervical fat pad were used to determine LH, while LA was identified by self-reported fat wasting of the face, neck, legs, arms or buttocks. Measurements were obtained with a scientific caliper for infraorbital, buccal, and submandibular skinfolds, and using an inelastic tape to measure circumferences of waist, hip, neck, and arm. LH and LA were established by the presence of at least one self-reported sign. RESULTS: Comparisons of self-reported signs with objective measurements for men and women were carried out in 815 participants on ART, out of 1240 participants with HIV infection. Self-report of decreased facial fat and sunken cheeks was associated with lower infraorbital, buccal, and submandibular skinfolds. Participants who reported buffalo hump had, on average, greater neck circumference, as well as those who have increased waist circumference also reported abdominal enlargement, but no buttock wasting. Men were most commonly affected by lipoatrophy (73 vs. 53%; P < 0.001), and women by lipohypertrophy (79 vs. 56%; P < 0.001). CONCLUSION: In conclusion, self-reported signs of lipodystrophy and lipoatrophy are prevalent, differ by gender, and are associated with objective measurements in people living with HIV/AIDS.Não há.2019-07-26T21:29:26Z2020-11-26T17:33:11Z2019-07-26T21:29:26Z2020-11-26T17:33:11Z2017info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article40application/pdfjaneiro1756-0500https://repositorio.animaeducacao.com.br/handle/ANIMA/261210Reino UnidoAttribution-NonCommercial-NoDerivs 3.0 Brazilhttp://creativecommons.org/licenses/by-nc-nd/3.0/br/info:eu-repo/semantics/openAccessAlencastro, Paulo RicardoBarcellos, Nêmora TWolff, Fernando HIkeda, Maria Letícia RodriguesSchuelter-Trevisol, FabianaBrandão, Ajácio M BFuchs, Sandra Cengreponame:Repositório Universitário da Ânima (RUNA)instname:Ânima Educaçãoinstacron:Ânima2021-08-11T17:59:35Zoai:repositorio.animaeducacao.com.br:ANIMA/2612Repositório InstitucionalPRIhttps://repositorio.animaeducacao.com.br/oai/requestcontato@animaeducacao.com.bropendoar:2021-08-11T17:59:35Repositório Universitário da Ânima (RUNA) - Ânima Educaçãofalse |
dc.title.none.fl_str_mv |
People living with HIV on ART have accurate perception of lipodystrophy signs: a cross‑sectional study |
title |
People living with HIV on ART have accurate perception of lipodystrophy signs: a cross‑sectional study |
spellingShingle |
People living with HIV on ART have accurate perception of lipodystrophy signs: a cross‑sectional study Alencastro, Paulo Ricardo HIV AIDS Lipodystrophy Lypohypertrophy Lipoatrophy |
title_short |
People living with HIV on ART have accurate perception of lipodystrophy signs: a cross‑sectional study |
title_full |
People living with HIV on ART have accurate perception of lipodystrophy signs: a cross‑sectional study |
title_fullStr |
People living with HIV on ART have accurate perception of lipodystrophy signs: a cross‑sectional study |
title_full_unstemmed |
People living with HIV on ART have accurate perception of lipodystrophy signs: a cross‑sectional study |
title_sort |
People living with HIV on ART have accurate perception of lipodystrophy signs: a cross‑sectional study |
author |
Alencastro, Paulo Ricardo |
author_facet |
Alencastro, Paulo Ricardo Barcellos, Nêmora T Wolff, Fernando H Ikeda, Maria Letícia Rodrigues Schuelter-Trevisol, Fabiana Brandão, Ajácio M B Fuchs, Sandra C |
author_role |
author |
author2 |
Barcellos, Nêmora T Wolff, Fernando H Ikeda, Maria Letícia Rodrigues Schuelter-Trevisol, Fabiana Brandão, Ajácio M B Fuchs, Sandra C |
author2_role |
author author author author author author |
dc.contributor.author.fl_str_mv |
Alencastro, Paulo Ricardo Barcellos, Nêmora T Wolff, Fernando H Ikeda, Maria Letícia Rodrigues Schuelter-Trevisol, Fabiana Brandão, Ajácio M B Fuchs, Sandra C |
dc.subject.por.fl_str_mv |
HIV AIDS Lipodystrophy Lypohypertrophy Lipoatrophy |
topic |
HIV AIDS Lipodystrophy Lypohypertrophy Lipoatrophy |
description |
BACKGROUND: The prevalence of lipodystrophy ranges from 31 to 65%, depending on the criteria adopted for diagnosis. The usual methods applied in the diagnosis vary from self-perception, medical examination, skinfolds measurements, or even imaging assessment for confirmation of fat distribution changes. Although several methods have been developed, there is no gold standard for characterization of LA and LH, or mixed forms. This study aimed to compare self-reported signs of lipodystrophy with objective measures by skinfolds and circumferences, and to evaluate the prevalence of lipoatrophy (LA) and lipohypertrophy (LH) among subjects living with HIV/AIDS on ART. METHODS: A cross-sectional study enrolled participants living with HIV/AIDS receiving ART, aged 18 years or older from an outpatient health care center, in Southern Brazil. Self-reported body fat enlargement in the abdomen, chest or breasts, and dorsocervical fat pad were used to determine LH, while LA was identified by self-reported fat wasting of the face, neck, legs, arms or buttocks. Measurements were obtained with a scientific caliper for infraorbital, buccal, and submandibular skinfolds, and using an inelastic tape to measure circumferences of waist, hip, neck, and arm. LH and LA were established by the presence of at least one self-reported sign. RESULTS: Comparisons of self-reported signs with objective measurements for men and women were carried out in 815 participants on ART, out of 1240 participants with HIV infection. Self-report of decreased facial fat and sunken cheeks was associated with lower infraorbital, buccal, and submandibular skinfolds. Participants who reported buffalo hump had, on average, greater neck circumference, as well as those who have increased waist circumference also reported abdominal enlargement, but no buttock wasting. Men were most commonly affected by lipoatrophy (73 vs. 53%; P < 0.001), and women by lipohypertrophy (79 vs. 56%; P < 0.001). CONCLUSION: In conclusion, self-reported signs of lipodystrophy and lipoatrophy are prevalent, differ by gender, and are associated with objective measurements in people living with HIV/AIDS. |
publishDate |
2017 |
dc.date.none.fl_str_mv |
2017 2019-07-26T21:29:26Z 2019-07-26T21:29:26Z 2020-11-26T17:33:11Z 2020-11-26T17:33:11Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
janeiro 1756-0500 https://repositorio.animaeducacao.com.br/handle/ANIMA/2612 |
identifier_str_mv |
janeiro 1756-0500 |
url |
https://repositorio.animaeducacao.com.br/handle/ANIMA/2612 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10 |
dc.rights.driver.fl_str_mv |
Attribution-NonCommercial-NoDerivs 3.0 Brazil http://creativecommons.org/licenses/by-nc-nd/3.0/br/ info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Attribution-NonCommercial-NoDerivs 3.0 Brazil http://creativecommons.org/licenses/by-nc-nd/3.0/br/ |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
40 application/pdf |
dc.coverage.none.fl_str_mv |
Reino Unido |
dc.source.none.fl_str_mv |
reponame:Repositório Universitário da Ânima (RUNA) instname:Ânima Educação instacron:Ânima |
instname_str |
Ânima Educação |
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reponame_str |
Repositório Universitário da Ânima (RUNA) |
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Repositório Universitário da Ânima (RUNA) |
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Repositório Universitário da Ânima (RUNA) - Ânima Educação |
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contato@animaeducacao.com.br |
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1767415802469810176 |