Soluble fractalkine in the plasma of fibromyalgia patients

Detalhes bibliográficos
Autor(a) principal: GARCIA,JUAN J.
Data de Publicação: 2014
Outros Autores: ORTEGA,EDUARDO
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Anais da Academia Brasileira de Ciências (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652014000401915
Resumo: Fibromyalgia is a form of non-articular rheumatism in which inflammatory cytokines seem to be involved. However, there is still no analytical specific diagnostic criterion for this disease. The aim was to examine a possible role of fractalkine as a biomarker in fibromyalgia. Plasma levels of soluble fractalkine were compared between women diagnosed with fibromyalgia (n=17) and healthy women (n=10) as controls. Fractalkine released by monocytes was also evaluated. Fibromyalgia patients showed lower plasma fractalkine than healthy women. Since most inflammatory pathologies show elevated plasma levels of soluble fractalkine, the results may contribute towards a differential diagnosis for fibromyalgia.
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spelling Soluble fractalkine in the plasma of fibromyalgia patientsfractalkinefibromyalgiabiomarkerchemokinemonocyteFibromyalgia is a form of non-articular rheumatism in which inflammatory cytokines seem to be involved. However, there is still no analytical specific diagnostic criterion for this disease. The aim was to examine a possible role of fractalkine as a biomarker in fibromyalgia. Plasma levels of soluble fractalkine were compared between women diagnosed with fibromyalgia (n=17) and healthy women (n=10) as controls. Fractalkine released by monocytes was also evaluated. Fibromyalgia patients showed lower plasma fractalkine than healthy women. Since most inflammatory pathologies show elevated plasma levels of soluble fractalkine, the results may contribute towards a differential diagnosis for fibromyalgia.Academia Brasileira de Ciências2014-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652014000401915Anais da Academia Brasileira de Ciências v.86 n.4 2014reponame:Anais da Academia Brasileira de Ciências (Online)instname:Academia Brasileira de Ciências (ABC)instacron:ABC10.1590/0001-3765201420130081info:eu-repo/semantics/openAccessGARCIA,JUAN J.ORTEGA,EDUARDOeng2015-10-27T00:00:00Zoai:scielo:S0001-37652014000401915Revistahttp://www.scielo.br/aabchttps://old.scielo.br/oai/scielo-oai.php||aabc@abc.org.br1678-26900001-3765opendoar:2015-10-27T00:00Anais da Academia Brasileira de Ciências (Online) - Academia Brasileira de Ciências (ABC)false
dc.title.none.fl_str_mv Soluble fractalkine in the plasma of fibromyalgia patients
title Soluble fractalkine in the plasma of fibromyalgia patients
spellingShingle Soluble fractalkine in the plasma of fibromyalgia patients
GARCIA,JUAN J.
fractalkine
fibromyalgia
biomarker
chemokine
monocyte
title_short Soluble fractalkine in the plasma of fibromyalgia patients
title_full Soluble fractalkine in the plasma of fibromyalgia patients
title_fullStr Soluble fractalkine in the plasma of fibromyalgia patients
title_full_unstemmed Soluble fractalkine in the plasma of fibromyalgia patients
title_sort Soluble fractalkine in the plasma of fibromyalgia patients
author GARCIA,JUAN J.
author_facet GARCIA,JUAN J.
ORTEGA,EDUARDO
author_role author
author2 ORTEGA,EDUARDO
author2_role author
dc.contributor.author.fl_str_mv GARCIA,JUAN J.
ORTEGA,EDUARDO
dc.subject.por.fl_str_mv fractalkine
fibromyalgia
biomarker
chemokine
monocyte
topic fractalkine
fibromyalgia
biomarker
chemokine
monocyte
description Fibromyalgia is a form of non-articular rheumatism in which inflammatory cytokines seem to be involved. However, there is still no analytical specific diagnostic criterion for this disease. The aim was to examine a possible role of fractalkine as a biomarker in fibromyalgia. Plasma levels of soluble fractalkine were compared between women diagnosed with fibromyalgia (n=17) and healthy women (n=10) as controls. Fractalkine released by monocytes was also evaluated. Fibromyalgia patients showed lower plasma fractalkine than healthy women. Since most inflammatory pathologies show elevated plasma levels of soluble fractalkine, the results may contribute towards a differential diagnosis for fibromyalgia.
publishDate 2014
dc.date.none.fl_str_mv 2014-12-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/0001-3765201420130081
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dc.publisher.none.fl_str_mv Academia Brasileira de Ciências
publisher.none.fl_str_mv Academia Brasileira de Ciências
dc.source.none.fl_str_mv Anais da Academia Brasileira de Ciências v.86 n.4 2014
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