The brain decade in debate: II. Panic or anxiety? From animal models to a neurobiological basis
Autor(a) principal: | |
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Data de Publicação: | 2001 |
Outros Autores: | , , , , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Brazilian Journal of Medical and Biological Research |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2001000200001 |
Resumo: | This article is a transcription of an electronic symposium sponsored by the Brazilian Society of Neuroscience and Behavior (SBNeC). Invited researchers from the European Union, North America and Brazil discussed two issues on anxiety, namely whether panic is a very intense anxiety or something else, and what aspects of clinical anxiety are reproduced by animal models. Concerning the first issue, most participants agreed that generalized anxiety and panic disorder are different on the basis of clinical manifestations, drug response and animal models. Also, underlying brain structures, neurotransmitter modulation and hormonal changes seem to involve important differences. It is also common knowledge that existing animal models generate different types of fear/anxiety. A challenge for future research is to establish a good correlation between animal models and nosological classification. |
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The brain decade in debate: II. Panic or anxiety? From animal models to a neurobiological basispanicanxietyfearanxiolytics5-HTbenzodiazepinesserotoninamygdalaperiaqueductal gray matteranimal modelsThis article is a transcription of an electronic symposium sponsored by the Brazilian Society of Neuroscience and Behavior (SBNeC). Invited researchers from the European Union, North America and Brazil discussed two issues on anxiety, namely whether panic is a very intense anxiety or something else, and what aspects of clinical anxiety are reproduced by animal models. Concerning the first issue, most participants agreed that generalized anxiety and panic disorder are different on the basis of clinical manifestations, drug response and animal models. Also, underlying brain structures, neurotransmitter modulation and hormonal changes seem to involve important differences. It is also common knowledge that existing animal models generate different types of fear/anxiety. A challenge for future research is to establish a good correlation between animal models and nosological classification.Associação Brasileira de Divulgação Científica2001-02-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2001000200001Brazilian Journal of Medical and Biological Research v.34 n.2 2001reponame:Brazilian Journal of Medical and Biological Researchinstname:Associação Brasileira de Divulgação Científica (ABDC)instacron:ABDC10.1590/S0100-879X2001000200001info:eu-repo/semantics/openAccessAndreatini,R.Blanchard,C.Blanchard,R.Brandão,M.L.Carobrez,A.P.Griebel,G.Guimarães,F.S.Handley,S.L.Jenck,F.Leite,J.R.Rodgers,J.Schenberg,L.C.Da Cunha,C.Graeff,F.G.eng2001-02-09T00:00:00Zoai:scielo:S0100-879X2001000200001Revistahttps://www.bjournal.org/https://old.scielo.br/oai/scielo-oai.phpbjournal@terra.com.br||bjournal@terra.com.br1414-431X0100-879Xopendoar:2001-02-09T00:00Brazilian Journal of Medical and Biological Research - Associação Brasileira de Divulgação Científica (ABDC)false |
dc.title.none.fl_str_mv |
The brain decade in debate: II. Panic or anxiety? From animal models to a neurobiological basis |
title |
The brain decade in debate: II. Panic or anxiety? From animal models to a neurobiological basis |
spellingShingle |
The brain decade in debate: II. Panic or anxiety? From animal models to a neurobiological basis Andreatini,R. panic anxiety fear anxiolytics 5-HT benzodiazepines serotonin amygdala periaqueductal gray matter animal models |
title_short |
The brain decade in debate: II. Panic or anxiety? From animal models to a neurobiological basis |
title_full |
The brain decade in debate: II. Panic or anxiety? From animal models to a neurobiological basis |
title_fullStr |
The brain decade in debate: II. Panic or anxiety? From animal models to a neurobiological basis |
title_full_unstemmed |
The brain decade in debate: II. Panic or anxiety? From animal models to a neurobiological basis |
title_sort |
The brain decade in debate: II. Panic or anxiety? From animal models to a neurobiological basis |
author |
Andreatini,R. |
author_facet |
Andreatini,R. Blanchard,C. Blanchard,R. Brandão,M.L. Carobrez,A.P. Griebel,G. Guimarães,F.S. Handley,S.L. Jenck,F. Leite,J.R. Rodgers,J. Schenberg,L.C. Da Cunha,C. Graeff,F.G. |
author_role |
author |
author2 |
Blanchard,C. Blanchard,R. Brandão,M.L. Carobrez,A.P. Griebel,G. Guimarães,F.S. Handley,S.L. Jenck,F. Leite,J.R. Rodgers,J. Schenberg,L.C. Da Cunha,C. Graeff,F.G. |
author2_role |
author author author author author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Andreatini,R. Blanchard,C. Blanchard,R. Brandão,M.L. Carobrez,A.P. Griebel,G. Guimarães,F.S. Handley,S.L. Jenck,F. Leite,J.R. Rodgers,J. Schenberg,L.C. Da Cunha,C. Graeff,F.G. |
dc.subject.por.fl_str_mv |
panic anxiety fear anxiolytics 5-HT benzodiazepines serotonin amygdala periaqueductal gray matter animal models |
topic |
panic anxiety fear anxiolytics 5-HT benzodiazepines serotonin amygdala periaqueductal gray matter animal models |
description |
This article is a transcription of an electronic symposium sponsored by the Brazilian Society of Neuroscience and Behavior (SBNeC). Invited researchers from the European Union, North America and Brazil discussed two issues on anxiety, namely whether panic is a very intense anxiety or something else, and what aspects of clinical anxiety are reproduced by animal models. Concerning the first issue, most participants agreed that generalized anxiety and panic disorder are different on the basis of clinical manifestations, drug response and animal models. Also, underlying brain structures, neurotransmitter modulation and hormonal changes seem to involve important differences. It is also common knowledge that existing animal models generate different types of fear/anxiety. A challenge for future research is to establish a good correlation between animal models and nosological classification. |
publishDate |
2001 |
dc.date.none.fl_str_mv |
2001-02-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2001000200001 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2001000200001 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S0100-879X2001000200001 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Associação Brasileira de Divulgação Científica |
publisher.none.fl_str_mv |
Associação Brasileira de Divulgação Científica |
dc.source.none.fl_str_mv |
Brazilian Journal of Medical and Biological Research v.34 n.2 2001 reponame:Brazilian Journal of Medical and Biological Research instname:Associação Brasileira de Divulgação Científica (ABDC) instacron:ABDC |
instname_str |
Associação Brasileira de Divulgação Científica (ABDC) |
instacron_str |
ABDC |
institution |
ABDC |
reponame_str |
Brazilian Journal of Medical and Biological Research |
collection |
Brazilian Journal of Medical and Biological Research |
repository.name.fl_str_mv |
Brazilian Journal of Medical and Biological Research - Associação Brasileira de Divulgação Científica (ABDC) |
repository.mail.fl_str_mv |
bjournal@terra.com.br||bjournal@terra.com.br |
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1754302930897338368 |