HB D Los Angeles in a Brazilian family

Detalhes bibliográficos
Autor(a) principal: Leoneli,Guilherme G.
Data de Publicação: 2001
Outros Autores: Melo,Silma M.A., Zago,Marco A., Silva Jr.,Wilson A., Bonini-Domingos,Cláudia R.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista brasileira de hematologia e hemoterapia (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-84842001000300004
Resumo: Inherited disorders of hemoglobin, the most common monogenic disease, are now well understood at the molecular level, knowledge, which has led to considerable improvements in their control and management. The Brazilian population is multiethnic, and the correct characterization of the Hb D is important, mainly because the method available for detection of abnormal hemoglobins, present a migration in the same zone at alkaline pH, for Hb S, D, and G for example. In this paper we studied a family with an abnormal hemoglobin like S in alkaline electrophoresis, by appropriated methods including HPLC and molecular analysis, characterized as hemoglobin D Los Angeles.
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spelling HB D Los Angeles in a Brazilian familyHemoglobin Dvariant hemoglobinpolymorphism hemoglobinInherited disorders of hemoglobin, the most common monogenic disease, are now well understood at the molecular level, knowledge, which has led to considerable improvements in their control and management. The Brazilian population is multiethnic, and the correct characterization of the Hb D is important, mainly because the method available for detection of abnormal hemoglobins, present a migration in the same zone at alkaline pH, for Hb S, D, and G for example. In this paper we studied a family with an abnormal hemoglobin like S in alkaline electrophoresis, by appropriated methods including HPLC and molecular analysis, characterized as hemoglobin D Los Angeles.Associação Brasileira de Hematologia e Hemoterapia e Terapia Celular2001-09-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-84842001000300004Revista Brasileira de Hematologia e Hemoterapia v.23 n.3 2001reponame:Revista brasileira de hematologia e hemoterapia (Online)instname:Associação Brasileira de Hematologia e Hemoterapia e Terapia Celular (ABHHTC)instacron:ABHHTC10.1590/S1516-84842001000300004info:eu-repo/semantics/openAccessLeoneli,Guilherme G.Melo,Silma M.A.Zago,Marco A.Silva Jr.,Wilson A.Bonini-Domingos,Cláudia R.eng2002-08-12T00:00:00Zoai:scielo:S1516-84842001000300004Revistahttp://www.rbhh.org/pt/archivo/https://old.scielo.br/oai/scielo-oai.phpsbhh@terra.com.br||secretaria@rbhh.org1806-08701516-8484opendoar:2002-08-12T00:00Revista brasileira de hematologia e hemoterapia (Online) - Associação Brasileira de Hematologia e Hemoterapia e Terapia Celular (ABHHTC)false
dc.title.none.fl_str_mv HB D Los Angeles in a Brazilian family
title HB D Los Angeles in a Brazilian family
spellingShingle HB D Los Angeles in a Brazilian family
Leoneli,Guilherme G.
Hemoglobin D
variant hemoglobin
polymorphism hemoglobin
title_short HB D Los Angeles in a Brazilian family
title_full HB D Los Angeles in a Brazilian family
title_fullStr HB D Los Angeles in a Brazilian family
title_full_unstemmed HB D Los Angeles in a Brazilian family
title_sort HB D Los Angeles in a Brazilian family
author Leoneli,Guilherme G.
author_facet Leoneli,Guilherme G.
Melo,Silma M.A.
Zago,Marco A.
Silva Jr.,Wilson A.
Bonini-Domingos,Cláudia R.
author_role author
author2 Melo,Silma M.A.
Zago,Marco A.
Silva Jr.,Wilson A.
Bonini-Domingos,Cláudia R.
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Leoneli,Guilherme G.
Melo,Silma M.A.
Zago,Marco A.
Silva Jr.,Wilson A.
Bonini-Domingos,Cláudia R.
dc.subject.por.fl_str_mv Hemoglobin D
variant hemoglobin
polymorphism hemoglobin
topic Hemoglobin D
variant hemoglobin
polymorphism hemoglobin
description Inherited disorders of hemoglobin, the most common monogenic disease, are now well understood at the molecular level, knowledge, which has led to considerable improvements in their control and management. The Brazilian population is multiethnic, and the correct characterization of the Hb D is important, mainly because the method available for detection of abnormal hemoglobins, present a migration in the same zone at alkaline pH, for Hb S, D, and G for example. In this paper we studied a family with an abnormal hemoglobin like S in alkaline electrophoresis, by appropriated methods including HPLC and molecular analysis, characterized as hemoglobin D Los Angeles.
publishDate 2001
dc.date.none.fl_str_mv 2001-09-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-84842001000300004
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-84842001000300004
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S1516-84842001000300004
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Associação Brasileira de Hematologia e Hemoterapia e Terapia Celular
publisher.none.fl_str_mv Associação Brasileira de Hematologia e Hemoterapia e Terapia Celular
dc.source.none.fl_str_mv Revista Brasileira de Hematologia e Hemoterapia v.23 n.3 2001
reponame:Revista brasileira de hematologia e hemoterapia (Online)
instname:Associação Brasileira de Hematologia e Hemoterapia e Terapia Celular (ABHHTC)
instacron:ABHHTC
instname_str Associação Brasileira de Hematologia e Hemoterapia e Terapia Celular (ABHHTC)
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institution ABHHTC
reponame_str Revista brasileira de hematologia e hemoterapia (Online)
collection Revista brasileira de hematologia e hemoterapia (Online)
repository.name.fl_str_mv Revista brasileira de hematologia e hemoterapia (Online) - Associação Brasileira de Hematologia e Hemoterapia e Terapia Celular (ABHHTC)
repository.mail.fl_str_mv sbhh@terra.com.br||secretaria@rbhh.org
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