Neurological congenital malformations in a tertiary hospital in south Brazil
Main Author: | |
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Publication Date: | 2009 |
Other Authors: | , , , , , |
Format: | Article |
Language: | eng |
Source: | Arquivos de neuro-psiquiatria (Online) |
Download full: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2009000500005 |
Summary: | BACKGROUND: Congenital anomalies are one of the main causes of morbidity and mortality among infants. The involvement of the central nervous system (CNS) occurs in 21% of cases. OBJECTIVE: To identify incidence of CNS malformations and associated factors in newborns at a Terciary Hospital of Porto Alegre. METHOD: Case-control study conducted between 2000 and 2005 based on the Latin American Collaborative Study of Congenital Malformations database. RESULTS: Among 26,588 births registered in this period, 3.67% presented with malformations (IC=95%; 3.44-3.9), being 0.36% of the CNS (IC=95%,(0.29-0.43)). The most common CNS malformation was meningomielocele (10.4%). Young maternal age (p=0.005); low birth weight (p=0.015); large cephalic perimeter (p=0.003); post term birth (p=0.000) and low APGAR indexes at the 1st and 5th minutes were associated with CNS malformations. CONCLUSION: We found an incidence of CNS malformations similar as compared to literature. |
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Neurological congenital malformations in a tertiary hospital in south Brazilneurological malformationsneural tube defectsrisk factorscongenital malformationsBACKGROUND: Congenital anomalies are one of the main causes of morbidity and mortality among infants. The involvement of the central nervous system (CNS) occurs in 21% of cases. OBJECTIVE: To identify incidence of CNS malformations and associated factors in newborns at a Terciary Hospital of Porto Alegre. METHOD: Case-control study conducted between 2000 and 2005 based on the Latin American Collaborative Study of Congenital Malformations database. RESULTS: Among 26,588 births registered in this period, 3.67% presented with malformations (IC=95%; 3.44-3.9), being 0.36% of the CNS (IC=95%,(0.29-0.43)). The most common CNS malformation was meningomielocele (10.4%). Young maternal age (p=0.005); low birth weight (p=0.015); large cephalic perimeter (p=0.003); post term birth (p=0.000) and low APGAR indexes at the 1st and 5th minutes were associated with CNS malformations. CONCLUSION: We found an incidence of CNS malformations similar as compared to literature.Academia Brasileira de Neurologia - ABNEURO2009-09-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2009000500005Arquivos de Neuro-Psiquiatria v.67 n.3b 2009reponame:Arquivos de neuro-psiquiatria (Online)instname:Academia Brasileira de Neurologiainstacron:ABNEURO10.1590/S0004-282X2009000500005info:eu-repo/semantics/openAccessGuardiola,AnaKoltermann,VanessaAguiar,Paula MusaGrossi,Sérgio PillaFleck,ValériaPereira,Elisabeth C.Pellanda,Lúciaeng2009-10-13T00:00:00Zoai:scielo:S0004-282X2009000500005Revistahttp://www.scielo.br/anphttps://old.scielo.br/oai/scielo-oai.php||revista.arquivos@abneuro.org1678-42270004-282Xopendoar:2009-10-13T00:00Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologiafalse |
dc.title.none.fl_str_mv |
Neurological congenital malformations in a tertiary hospital in south Brazil |
title |
Neurological congenital malformations in a tertiary hospital in south Brazil |
spellingShingle |
Neurological congenital malformations in a tertiary hospital in south Brazil Guardiola,Ana neurological malformations neural tube defects risk factors congenital malformations |
title_short |
Neurological congenital malformations in a tertiary hospital in south Brazil |
title_full |
Neurological congenital malformations in a tertiary hospital in south Brazil |
title_fullStr |
Neurological congenital malformations in a tertiary hospital in south Brazil |
title_full_unstemmed |
Neurological congenital malformations in a tertiary hospital in south Brazil |
title_sort |
Neurological congenital malformations in a tertiary hospital in south Brazil |
author |
Guardiola,Ana |
author_facet |
Guardiola,Ana Koltermann,Vanessa Aguiar,Paula Musa Grossi,Sérgio Pilla Fleck,Valéria Pereira,Elisabeth C. Pellanda,Lúcia |
author_role |
author |
author2 |
Koltermann,Vanessa Aguiar,Paula Musa Grossi,Sérgio Pilla Fleck,Valéria Pereira,Elisabeth C. Pellanda,Lúcia |
author2_role |
author author author author author author |
dc.contributor.author.fl_str_mv |
Guardiola,Ana Koltermann,Vanessa Aguiar,Paula Musa Grossi,Sérgio Pilla Fleck,Valéria Pereira,Elisabeth C. Pellanda,Lúcia |
dc.subject.por.fl_str_mv |
neurological malformations neural tube defects risk factors congenital malformations |
topic |
neurological malformations neural tube defects risk factors congenital malformations |
description |
BACKGROUND: Congenital anomalies are one of the main causes of morbidity and mortality among infants. The involvement of the central nervous system (CNS) occurs in 21% of cases. OBJECTIVE: To identify incidence of CNS malformations and associated factors in newborns at a Terciary Hospital of Porto Alegre. METHOD: Case-control study conducted between 2000 and 2005 based on the Latin American Collaborative Study of Congenital Malformations database. RESULTS: Among 26,588 births registered in this period, 3.67% presented with malformations (IC=95%; 3.44-3.9), being 0.36% of the CNS (IC=95%,(0.29-0.43)). The most common CNS malformation was meningomielocele (10.4%). Young maternal age (p=0.005); low birth weight (p=0.015); large cephalic perimeter (p=0.003); post term birth (p=0.000) and low APGAR indexes at the 1st and 5th minutes were associated with CNS malformations. CONCLUSION: We found an incidence of CNS malformations similar as compared to literature. |
publishDate |
2009 |
dc.date.none.fl_str_mv |
2009-09-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2009000500005 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2009000500005 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S0004-282X2009000500005 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Academia Brasileira de Neurologia - ABNEURO |
publisher.none.fl_str_mv |
Academia Brasileira de Neurologia - ABNEURO |
dc.source.none.fl_str_mv |
Arquivos de Neuro-Psiquiatria v.67 n.3b 2009 reponame:Arquivos de neuro-psiquiatria (Online) instname:Academia Brasileira de Neurologia instacron:ABNEURO |
instname_str |
Academia Brasileira de Neurologia |
instacron_str |
ABNEURO |
institution |
ABNEURO |
reponame_str |
Arquivos de neuro-psiquiatria (Online) |
collection |
Arquivos de neuro-psiquiatria (Online) |
repository.name.fl_str_mv |
Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologia |
repository.mail.fl_str_mv |
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