Amyotrophic lateral sclerosis: prospective study on respiratory parameters

Detalhes bibliográficos
Autor(a) principal: Almeida,Sara Regina Meira
Data de Publicação: 2010
Outros Autores: Silva,Luciano Bruno C., Guerreiro,Carlos Alberto M., Nucci,Anamarli
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Arquivos de neuro-psiquiatria (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2010000200020
Resumo: OBJECTIVE: To verify how efficient respiratory parameters are in the follow-up of subjects with amyotrophic lateral sclerosis (ALS) and to observe possible correlations between respiratory and nutritional functions. METHOD: Sixteen patients with probable or defined ALS were selected and evaluated over eight months using the following respiratory parameters: spirometry, maximum inspiratory pressure (MIP), maximum expiratory pressure (MEP), arterial gasometry and pulse oximetry; and nutritional parameters such as body mass index (BMI) and percentage weight loss. RESULTS: PaCO2 was a significant parameter to follow up disease evolution (p=0.051). There was significant correlation between MIP and MEP (r: 0.83); BMI and MIP (r: 0.70); BMI and MEP (r: 0.72); pulse oximetry and forced vital capacity (r: 0.57). CONCLUSION: PaCO2 was shown to be an efficient and significant parameter in the measurement of respiratory impairment; the correlations among MIP, MEP and BMI indicated that these are significant parameters for periodic clinical evaluation.
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spelling Amyotrophic lateral sclerosis: prospective study on respiratory parametersamyotrophic lateral sclerosismaximum inspiratory pressure, maximum expiratory pressurebody mass indexOBJECTIVE: To verify how efficient respiratory parameters are in the follow-up of subjects with amyotrophic lateral sclerosis (ALS) and to observe possible correlations between respiratory and nutritional functions. METHOD: Sixteen patients with probable or defined ALS were selected and evaluated over eight months using the following respiratory parameters: spirometry, maximum inspiratory pressure (MIP), maximum expiratory pressure (MEP), arterial gasometry and pulse oximetry; and nutritional parameters such as body mass index (BMI) and percentage weight loss. RESULTS: PaCO2 was a significant parameter to follow up disease evolution (p=0.051). There was significant correlation between MIP and MEP (r: 0.83); BMI and MIP (r: 0.70); BMI and MEP (r: 0.72); pulse oximetry and forced vital capacity (r: 0.57). CONCLUSION: PaCO2 was shown to be an efficient and significant parameter in the measurement of respiratory impairment; the correlations among MIP, MEP and BMI indicated that these are significant parameters for periodic clinical evaluation.Academia Brasileira de Neurologia - ABNEURO2010-04-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2010000200020Arquivos de Neuro-Psiquiatria v.68 n.2 2010reponame:Arquivos de neuro-psiquiatria (Online)instname:Academia Brasileira de Neurologiainstacron:ABNEURO10.1590/S0004-282X2010000200020info:eu-repo/semantics/openAccessAlmeida,Sara Regina MeiraSilva,Luciano Bruno C.Guerreiro,Carlos Alberto M.Nucci,Anamarlieng2010-04-28T00:00:00Zoai:scielo:S0004-282X2010000200020Revistahttp://www.scielo.br/anphttps://old.scielo.br/oai/scielo-oai.php||revista.arquivos@abneuro.org1678-42270004-282Xopendoar:2010-04-28T00:00Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologiafalse
dc.title.none.fl_str_mv Amyotrophic lateral sclerosis: prospective study on respiratory parameters
title Amyotrophic lateral sclerosis: prospective study on respiratory parameters
spellingShingle Amyotrophic lateral sclerosis: prospective study on respiratory parameters
Almeida,Sara Regina Meira
amyotrophic lateral sclerosis
maximum inspiratory pressure, maximum expiratory pressure
body mass index
title_short Amyotrophic lateral sclerosis: prospective study on respiratory parameters
title_full Amyotrophic lateral sclerosis: prospective study on respiratory parameters
title_fullStr Amyotrophic lateral sclerosis: prospective study on respiratory parameters
title_full_unstemmed Amyotrophic lateral sclerosis: prospective study on respiratory parameters
title_sort Amyotrophic lateral sclerosis: prospective study on respiratory parameters
author Almeida,Sara Regina Meira
author_facet Almeida,Sara Regina Meira
Silva,Luciano Bruno C.
Guerreiro,Carlos Alberto M.
Nucci,Anamarli
author_role author
author2 Silva,Luciano Bruno C.
Guerreiro,Carlos Alberto M.
Nucci,Anamarli
author2_role author
author
author
dc.contributor.author.fl_str_mv Almeida,Sara Regina Meira
Silva,Luciano Bruno C.
Guerreiro,Carlos Alberto M.
Nucci,Anamarli
dc.subject.por.fl_str_mv amyotrophic lateral sclerosis
maximum inspiratory pressure, maximum expiratory pressure
body mass index
topic amyotrophic lateral sclerosis
maximum inspiratory pressure, maximum expiratory pressure
body mass index
description OBJECTIVE: To verify how efficient respiratory parameters are in the follow-up of subjects with amyotrophic lateral sclerosis (ALS) and to observe possible correlations between respiratory and nutritional functions. METHOD: Sixteen patients with probable or defined ALS were selected and evaluated over eight months using the following respiratory parameters: spirometry, maximum inspiratory pressure (MIP), maximum expiratory pressure (MEP), arterial gasometry and pulse oximetry; and nutritional parameters such as body mass index (BMI) and percentage weight loss. RESULTS: PaCO2 was a significant parameter to follow up disease evolution (p=0.051). There was significant correlation between MIP and MEP (r: 0.83); BMI and MIP (r: 0.70); BMI and MEP (r: 0.72); pulse oximetry and forced vital capacity (r: 0.57). CONCLUSION: PaCO2 was shown to be an efficient and significant parameter in the measurement of respiratory impairment; the correlations among MIP, MEP and BMI indicated that these are significant parameters for periodic clinical evaluation.
publishDate 2010
dc.date.none.fl_str_mv 2010-04-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
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status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2010000200020
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dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0004-282X2010000200020
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
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dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Academia Brasileira de Neurologia - ABNEURO
publisher.none.fl_str_mv Academia Brasileira de Neurologia - ABNEURO
dc.source.none.fl_str_mv Arquivos de Neuro-Psiquiatria v.68 n.2 2010
reponame:Arquivos de neuro-psiquiatria (Online)
instname:Academia Brasileira de Neurologia
instacron:ABNEURO
instname_str Academia Brasileira de Neurologia
instacron_str ABNEURO
institution ABNEURO
reponame_str Arquivos de neuro-psiquiatria (Online)
collection Arquivos de neuro-psiquiatria (Online)
repository.name.fl_str_mv Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologia
repository.mail.fl_str_mv ||revista.arquivos@abneuro.org
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