Neurological complications after H1N1 influenza vaccination: magnetic resonance imaging findings
Autor(a) principal: | |
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Data de Publicação: | 2014 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Arquivos de neuro-psiquiatria (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2014000700496 |
Resumo: | Objective: To report 4 different neurological complications of H1N1 virus vaccination. Method: Four patients (9, 16, 37 and 69 years of age) had neurological symptoms (intracranial hypertension, ataxia, left peripheral facial palsy of abrupt onset, altered mental status, myelitis) starting 4-15 days after H1N1 vaccination. MRI was obtained during the acute period. Results: One patient with high T2 signal in the cerebellum interpreted as acute cerebellitis; another, with left facial palsy, showed contrast enhancement within both internal auditory canals was present, however it was more important in the right side; one patient showed gyriform hyperintensities on FLAIR with sulcal effacement in the right fronto-parietal region; and the last one showed findings compatible with thoracic myelitis. Conclusion: H1N1 vaccination can result in important neurological complications probably secondary to post-vaccination inflammation. MRI detected abnormalities in all patients. |
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Neurological complications after H1N1 influenza vaccination: magnetic resonance imaging findingscentral nervous systeminfluenza A virusH1N1magnetic resonance imagingencephalitis after vaccination Objective: To report 4 different neurological complications of H1N1 virus vaccination. Method: Four patients (9, 16, 37 and 69 years of age) had neurological symptoms (intracranial hypertension, ataxia, left peripheral facial palsy of abrupt onset, altered mental status, myelitis) starting 4-15 days after H1N1 vaccination. MRI was obtained during the acute period. Results: One patient with high T2 signal in the cerebellum interpreted as acute cerebellitis; another, with left facial palsy, showed contrast enhancement within both internal auditory canals was present, however it was more important in the right side; one patient showed gyriform hyperintensities on FLAIR with sulcal effacement in the right fronto-parietal region; and the last one showed findings compatible with thoracic myelitis. Conclusion: H1N1 vaccination can result in important neurological complications probably secondary to post-vaccination inflammation. MRI detected abnormalities in all patients. Academia Brasileira de Neurologia - ABNEURO2014-07-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2014000700496Arquivos de Neuro-Psiquiatria v.72 n.7 2014reponame:Arquivos de neuro-psiquiatria (Online)instname:Academia Brasileira de Neurologiainstacron:ABNEURO10.1590/0004-282X20140064info:eu-repo/semantics/openAccessLessa,RonaldoCastillo,MaurícioAzevedo,RenataAzevedo,FernandaAzevedo,Hildoeng2014-07-14T00:00:00Zoai:scielo:S0004-282X2014000700496Revistahttp://www.scielo.br/anphttps://old.scielo.br/oai/scielo-oai.php||revista.arquivos@abneuro.org1678-42270004-282Xopendoar:2014-07-14T00:00Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologiafalse |
dc.title.none.fl_str_mv |
Neurological complications after H1N1 influenza vaccination: magnetic resonance imaging findings |
title |
Neurological complications after H1N1 influenza vaccination: magnetic resonance imaging findings |
spellingShingle |
Neurological complications after H1N1 influenza vaccination: magnetic resonance imaging findings Lessa,Ronaldo central nervous system influenza A virus H1N1 magnetic resonance imaging encephalitis after vaccination |
title_short |
Neurological complications after H1N1 influenza vaccination: magnetic resonance imaging findings |
title_full |
Neurological complications after H1N1 influenza vaccination: magnetic resonance imaging findings |
title_fullStr |
Neurological complications after H1N1 influenza vaccination: magnetic resonance imaging findings |
title_full_unstemmed |
Neurological complications after H1N1 influenza vaccination: magnetic resonance imaging findings |
title_sort |
Neurological complications after H1N1 influenza vaccination: magnetic resonance imaging findings |
author |
Lessa,Ronaldo |
author_facet |
Lessa,Ronaldo Castillo,Maurício Azevedo,Renata Azevedo,Fernanda Azevedo,Hildo |
author_role |
author |
author2 |
Castillo,Maurício Azevedo,Renata Azevedo,Fernanda Azevedo,Hildo |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Lessa,Ronaldo Castillo,Maurício Azevedo,Renata Azevedo,Fernanda Azevedo,Hildo |
dc.subject.por.fl_str_mv |
central nervous system influenza A virus H1N1 magnetic resonance imaging encephalitis after vaccination |
topic |
central nervous system influenza A virus H1N1 magnetic resonance imaging encephalitis after vaccination |
description |
Objective: To report 4 different neurological complications of H1N1 virus vaccination. Method: Four patients (9, 16, 37 and 69 years of age) had neurological symptoms (intracranial hypertension, ataxia, left peripheral facial palsy of abrupt onset, altered mental status, myelitis) starting 4-15 days after H1N1 vaccination. MRI was obtained during the acute period. Results: One patient with high T2 signal in the cerebellum interpreted as acute cerebellitis; another, with left facial palsy, showed contrast enhancement within both internal auditory canals was present, however it was more important in the right side; one patient showed gyriform hyperintensities on FLAIR with sulcal effacement in the right fronto-parietal region; and the last one showed findings compatible with thoracic myelitis. Conclusion: H1N1 vaccination can result in important neurological complications probably secondary to post-vaccination inflammation. MRI detected abnormalities in all patients. |
publishDate |
2014 |
dc.date.none.fl_str_mv |
2014-07-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2014000700496 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2014000700496 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/0004-282X20140064 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Academia Brasileira de Neurologia - ABNEURO |
publisher.none.fl_str_mv |
Academia Brasileira de Neurologia - ABNEURO |
dc.source.none.fl_str_mv |
Arquivos de Neuro-Psiquiatria v.72 n.7 2014 reponame:Arquivos de neuro-psiquiatria (Online) instname:Academia Brasileira de Neurologia instacron:ABNEURO |
instname_str |
Academia Brasileira de Neurologia |
instacron_str |
ABNEURO |
institution |
ABNEURO |
reponame_str |
Arquivos de neuro-psiquiatria (Online) |
collection |
Arquivos de neuro-psiquiatria (Online) |
repository.name.fl_str_mv |
Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologia |
repository.mail.fl_str_mv |
||revista.arquivos@abneuro.org |
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1754212776503410688 |