Morphoquantitative effects of acute diabetes on the myenteric neurons of the proximal colon of adult rats
Main Author: | |
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Publication Date: | 2002 |
Other Authors: | , |
Format: | Article |
Language: | eng |
Source: | Arquivos de neuro-psiquiatria (Online) |
Download full: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2002000400012 |
Summary: | The effects of acute diabetes on the density and size of the myenteric neurons of the proximal colon of adult rats were investigated. The injection of streptozotocin was followed by a period of observation of seven days, during which the diabetic animals showed weight loss, excessive food and water intake, large urinary debt and hyperglicemia. The whole-mounts from the proximal colon were stained with the techniques of Giemsa and of the NADH-diaphorase, and the employment of these techniques made it possible to verify a decrease on the neuronal density and on the cell body size of the myenteric neurons in the colon of the diabetic rats. These observations were discussed in terms of the pathophysiology of the diabetes and the experimental protocol. |
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Morphoquantitative effects of acute diabetes on the myenteric neurons of the proximal colon of adult ratsacute diabetesmyenteric neuronsproximal colonThe effects of acute diabetes on the density and size of the myenteric neurons of the proximal colon of adult rats were investigated. The injection of streptozotocin was followed by a period of observation of seven days, during which the diabetic animals showed weight loss, excessive food and water intake, large urinary debt and hyperglicemia. The whole-mounts from the proximal colon were stained with the techniques of Giemsa and of the NADH-diaphorase, and the employment of these techniques made it possible to verify a decrease on the neuronal density and on the cell body size of the myenteric neurons in the colon of the diabetic rats. These observations were discussed in terms of the pathophysiology of the diabetes and the experimental protocol.Academia Brasileira de Neurologia - ABNEURO2002-09-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2002000400012Arquivos de Neuro-Psiquiatria v.60 n.3A 2002reponame:Arquivos de neuro-psiquiatria (Online)instname:Academia Brasileira de Neurologiainstacron:ABNEURO10.1590/S0004-282X2002000400012info:eu-repo/semantics/openAccessFurlan,Maria Montserrat D.P.Molinari,Sônia L.Miranda Neto,Marcílio H. deeng2002-09-10T00:00:00Zoai:scielo:S0004-282X2002000400012Revistahttp://www.scielo.br/anphttps://old.scielo.br/oai/scielo-oai.php||revista.arquivos@abneuro.org1678-42270004-282Xopendoar:2002-09-10T00:00Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologiafalse |
dc.title.none.fl_str_mv |
Morphoquantitative effects of acute diabetes on the myenteric neurons of the proximal colon of adult rats |
title |
Morphoquantitative effects of acute diabetes on the myenteric neurons of the proximal colon of adult rats |
spellingShingle |
Morphoquantitative effects of acute diabetes on the myenteric neurons of the proximal colon of adult rats Furlan,Maria Montserrat D.P. acute diabetes myenteric neurons proximal colon |
title_short |
Morphoquantitative effects of acute diabetes on the myenteric neurons of the proximal colon of adult rats |
title_full |
Morphoquantitative effects of acute diabetes on the myenteric neurons of the proximal colon of adult rats |
title_fullStr |
Morphoquantitative effects of acute diabetes on the myenteric neurons of the proximal colon of adult rats |
title_full_unstemmed |
Morphoquantitative effects of acute diabetes on the myenteric neurons of the proximal colon of adult rats |
title_sort |
Morphoquantitative effects of acute diabetes on the myenteric neurons of the proximal colon of adult rats |
author |
Furlan,Maria Montserrat D.P. |
author_facet |
Furlan,Maria Montserrat D.P. Molinari,Sônia L. Miranda Neto,Marcílio H. de |
author_role |
author |
author2 |
Molinari,Sônia L. Miranda Neto,Marcílio H. de |
author2_role |
author author |
dc.contributor.author.fl_str_mv |
Furlan,Maria Montserrat D.P. Molinari,Sônia L. Miranda Neto,Marcílio H. de |
dc.subject.por.fl_str_mv |
acute diabetes myenteric neurons proximal colon |
topic |
acute diabetes myenteric neurons proximal colon |
description |
The effects of acute diabetes on the density and size of the myenteric neurons of the proximal colon of adult rats were investigated. The injection of streptozotocin was followed by a period of observation of seven days, during which the diabetic animals showed weight loss, excessive food and water intake, large urinary debt and hyperglicemia. The whole-mounts from the proximal colon were stained with the techniques of Giemsa and of the NADH-diaphorase, and the employment of these techniques made it possible to verify a decrease on the neuronal density and on the cell body size of the myenteric neurons in the colon of the diabetic rats. These observations were discussed in terms of the pathophysiology of the diabetes and the experimental protocol. |
publishDate |
2002 |
dc.date.none.fl_str_mv |
2002-09-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2002000400012 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2002000400012 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S0004-282X2002000400012 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Academia Brasileira de Neurologia - ABNEURO |
publisher.none.fl_str_mv |
Academia Brasileira de Neurologia - ABNEURO |
dc.source.none.fl_str_mv |
Arquivos de Neuro-Psiquiatria v.60 n.3A 2002 reponame:Arquivos de neuro-psiquiatria (Online) instname:Academia Brasileira de Neurologia instacron:ABNEURO |
instname_str |
Academia Brasileira de Neurologia |
instacron_str |
ABNEURO |
institution |
ABNEURO |
reponame_str |
Arquivos de neuro-psiquiatria (Online) |
collection |
Arquivos de neuro-psiquiatria (Online) |
repository.name.fl_str_mv |
Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologia |
repository.mail.fl_str_mv |
||revista.arquivos@abneuro.org |
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1754212754491703296 |