Clonidine in respiratory panic disorder subtype

Detalhes bibliográficos
Autor(a) principal: Valença,Alexandre M.
Data de Publicação: 2004
Outros Autores: Nardi,Antonio E., Mezzasalma,Marco A., Nascimento,Isabella, Lopes,Fabiana L., Zin,Walter A., Versiani,Marcio
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Arquivos de neuro-psiquiatria (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2004000300004
Resumo: OBJECTIVE: Clonidine, which inhibits locus coeruleus discharge, would seem for theoretical reasons to be a good antipanic drug. Panic disorder (PD) presents a heterogeneous cluster of symptoms and a classification based on subtypes has been suggested and the respiratory symptoms group appears as a distinct subtype. METHOD: We report three cases of respiratory PD patients who were successfully treated with clonidine. RESULTS: Patients obtained panic free status, reduced anxiety levels and better functioning after clonidine administration (0.30-0.45 mg/day) for 6 weeks. CONCLUSION: Clonidine can be effective in the treatment of respiratory PD. This drug might play a role in relieving symptoms of anxiety due to noradrenergic hyperactivity in these patients.
id ABNEURO-1_60b7e1173563602777ecc733d22a7817
oai_identifier_str oai:scielo:S0004-282X2004000300004
network_acronym_str ABNEURO-1
network_name_str Arquivos de neuro-psiquiatria (Online)
repository_id_str
spelling Clonidine in respiratory panic disorder subtyperespirationpanic attacknorepinephrinepanic subtypesanxiety disorderOBJECTIVE: Clonidine, which inhibits locus coeruleus discharge, would seem for theoretical reasons to be a good antipanic drug. Panic disorder (PD) presents a heterogeneous cluster of symptoms and a classification based on subtypes has been suggested and the respiratory symptoms group appears as a distinct subtype. METHOD: We report three cases of respiratory PD patients who were successfully treated with clonidine. RESULTS: Patients obtained panic free status, reduced anxiety levels and better functioning after clonidine administration (0.30-0.45 mg/day) for 6 weeks. CONCLUSION: Clonidine can be effective in the treatment of respiratory PD. This drug might play a role in relieving symptoms of anxiety due to noradrenergic hyperactivity in these patients.Academia Brasileira de Neurologia - ABNEURO2004-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2004000300004Arquivos de Neuro-Psiquiatria v.62 n.2b 2004reponame:Arquivos de neuro-psiquiatria (Online)instname:Academia Brasileira de Neurologiainstacron:ABNEURO10.1590/S0004-282X2004000300004info:eu-repo/semantics/openAccessValença,Alexandre M.Nardi,Antonio E.Mezzasalma,Marco A.Nascimento,IsabellaLopes,Fabiana L.Zin,Walter A.Versiani,Marcioeng2004-07-20T00:00:00Zoai:scielo:S0004-282X2004000300004Revistahttp://www.scielo.br/anphttps://old.scielo.br/oai/scielo-oai.php||revista.arquivos@abneuro.org1678-42270004-282Xopendoar:2004-07-20T00:00Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologiafalse
dc.title.none.fl_str_mv Clonidine in respiratory panic disorder subtype
title Clonidine in respiratory panic disorder subtype
spellingShingle Clonidine in respiratory panic disorder subtype
Valença,Alexandre M.
respiration
panic attack
norepinephrine
panic subtypes
anxiety disorder
title_short Clonidine in respiratory panic disorder subtype
title_full Clonidine in respiratory panic disorder subtype
title_fullStr Clonidine in respiratory panic disorder subtype
title_full_unstemmed Clonidine in respiratory panic disorder subtype
title_sort Clonidine in respiratory panic disorder subtype
author Valença,Alexandre M.
author_facet Valença,Alexandre M.
Nardi,Antonio E.
Mezzasalma,Marco A.
Nascimento,Isabella
Lopes,Fabiana L.
Zin,Walter A.
Versiani,Marcio
author_role author
author2 Nardi,Antonio E.
Mezzasalma,Marco A.
Nascimento,Isabella
Lopes,Fabiana L.
Zin,Walter A.
Versiani,Marcio
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Valença,Alexandre M.
Nardi,Antonio E.
Mezzasalma,Marco A.
Nascimento,Isabella
Lopes,Fabiana L.
Zin,Walter A.
Versiani,Marcio
dc.subject.por.fl_str_mv respiration
panic attack
norepinephrine
panic subtypes
anxiety disorder
topic respiration
panic attack
norepinephrine
panic subtypes
anxiety disorder
description OBJECTIVE: Clonidine, which inhibits locus coeruleus discharge, would seem for theoretical reasons to be a good antipanic drug. Panic disorder (PD) presents a heterogeneous cluster of symptoms and a classification based on subtypes has been suggested and the respiratory symptoms group appears as a distinct subtype. METHOD: We report three cases of respiratory PD patients who were successfully treated with clonidine. RESULTS: Patients obtained panic free status, reduced anxiety levels and better functioning after clonidine administration (0.30-0.45 mg/day) for 6 weeks. CONCLUSION: Clonidine can be effective in the treatment of respiratory PD. This drug might play a role in relieving symptoms of anxiety due to noradrenergic hyperactivity in these patients.
publishDate 2004
dc.date.none.fl_str_mv 2004-06-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2004000300004
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2004000300004
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0004-282X2004000300004
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Academia Brasileira de Neurologia - ABNEURO
publisher.none.fl_str_mv Academia Brasileira de Neurologia - ABNEURO
dc.source.none.fl_str_mv Arquivos de Neuro-Psiquiatria v.62 n.2b 2004
reponame:Arquivos de neuro-psiquiatria (Online)
instname:Academia Brasileira de Neurologia
instacron:ABNEURO
instname_str Academia Brasileira de Neurologia
instacron_str ABNEURO
institution ABNEURO
reponame_str Arquivos de neuro-psiquiatria (Online)
collection Arquivos de neuro-psiquiatria (Online)
repository.name.fl_str_mv Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologia
repository.mail.fl_str_mv ||revista.arquivos@abneuro.org
_version_ 1754212756966342656