Prevalence of multiple sclerosis in key cities of Brazil: a study in Passo Fundo, Southern Brazil
Autor(a) principal: | |
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Data de Publicação: | 2021 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Arquivos de neuro-psiquiatria (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2021000800692 |
Resumo: | ABSTRACT Background: To improve the comparability of multiple sclerosis (MS) prevalence across Brazilian regions, the Brazilian Committee for Treatment and Research in MS has implemented a standardized approach to assess the prevalence of the disease in five key cities, which were deemed representative of their regions in terms of socio-geographical features and where in-person revision of each case was feasible. Objective: To report the point-prevalence of MS in Passo Fundo, one of the key cities in Southern Brazil. Methods: We sought to identify all MS patients who were living in Passo Fundo on July 1st, 2015. The primary source for case ascertainment was records from the offices of neurologists and neurosurgeons practicing in the city. Multiple secondary sources were used to maximize identification of cases. All patients underwent in-person review of the diagnosis by a panel of neurologists with experience in MS. Results: We identified 52 MS patients living in Passo Fundo on July 1st, 2015. The point-prevalence rate for MS was 26.4/100,000 population (95% confidence interval, 19.7 to 34.6/100,000). Among the MS cases, 42 (80.8%) were female, for a sex ratio of 4.2:1. Forty-six cases (88.5%) were categorized as relapsing-remitting MS, and the remaining 6 cases, as secondary progressive MS (11.5%). Other epidemiological and clinical features were comparable to national and international MS populations. Conclusions: The prevalence of MS in Passo Fundo is one of the highest reported in Brazil so far. Studies in other key Brazilian cities, using the same methodology, are currently being carried out. |
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Arquivos de neuro-psiquiatria (Online) |
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Prevalence of multiple sclerosis in key cities of Brazil: a study in Passo Fundo, Southern BrazilMultiple SclerosisPrevalenceEpidemiologyABSTRACT Background: To improve the comparability of multiple sclerosis (MS) prevalence across Brazilian regions, the Brazilian Committee for Treatment and Research in MS has implemented a standardized approach to assess the prevalence of the disease in five key cities, which were deemed representative of their regions in terms of socio-geographical features and where in-person revision of each case was feasible. Objective: To report the point-prevalence of MS in Passo Fundo, one of the key cities in Southern Brazil. Methods: We sought to identify all MS patients who were living in Passo Fundo on July 1st, 2015. The primary source for case ascertainment was records from the offices of neurologists and neurosurgeons practicing in the city. Multiple secondary sources were used to maximize identification of cases. All patients underwent in-person review of the diagnosis by a panel of neurologists with experience in MS. Results: We identified 52 MS patients living in Passo Fundo on July 1st, 2015. The point-prevalence rate for MS was 26.4/100,000 population (95% confidence interval, 19.7 to 34.6/100,000). Among the MS cases, 42 (80.8%) were female, for a sex ratio of 4.2:1. Forty-six cases (88.5%) were categorized as relapsing-remitting MS, and the remaining 6 cases, as secondary progressive MS (11.5%). Other epidemiological and clinical features were comparable to national and international MS populations. Conclusions: The prevalence of MS in Passo Fundo is one of the highest reported in Brazil so far. Studies in other key Brazilian cities, using the same methodology, are currently being carried out.Academia Brasileira de Neurologia - ABNEURO2021-08-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2021000800692Arquivos de Neuro-Psiquiatria v.79 n.8 2021reponame:Arquivos de neuro-psiquiatria (Online)instname:Academia Brasileira de Neurologiainstacron:ABNEURO10.1590/0004-282x-anp-2020-0221info:eu-repo/semantics/openAccessPassos,Giordani Rodrigues dosBecker,JeffersonVarela,Daniel LimaFröhlich,Alan ChristmannRech,Bruna ConstantinoMattos,Ana Carolina Squeff deCallegaro,DagobertoLana-Peixoto,Marco Aurélioeng2021-09-17T00:00:00Zoai:scielo:S0004-282X2021000800692Revistahttp://www.scielo.br/anphttps://old.scielo.br/oai/scielo-oai.php||revista.arquivos@abneuro.org1678-42270004-282Xopendoar:2021-09-17T00:00Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologiafalse |
dc.title.none.fl_str_mv |
Prevalence of multiple sclerosis in key cities of Brazil: a study in Passo Fundo, Southern Brazil |
title |
Prevalence of multiple sclerosis in key cities of Brazil: a study in Passo Fundo, Southern Brazil |
spellingShingle |
Prevalence of multiple sclerosis in key cities of Brazil: a study in Passo Fundo, Southern Brazil Passos,Giordani Rodrigues dos Multiple Sclerosis Prevalence Epidemiology |
title_short |
Prevalence of multiple sclerosis in key cities of Brazil: a study in Passo Fundo, Southern Brazil |
title_full |
Prevalence of multiple sclerosis in key cities of Brazil: a study in Passo Fundo, Southern Brazil |
title_fullStr |
Prevalence of multiple sclerosis in key cities of Brazil: a study in Passo Fundo, Southern Brazil |
title_full_unstemmed |
Prevalence of multiple sclerosis in key cities of Brazil: a study in Passo Fundo, Southern Brazil |
title_sort |
Prevalence of multiple sclerosis in key cities of Brazil: a study in Passo Fundo, Southern Brazil |
author |
Passos,Giordani Rodrigues dos |
author_facet |
Passos,Giordani Rodrigues dos Becker,Jefferson Varela,Daniel Lima Fröhlich,Alan Christmann Rech,Bruna Constantino Mattos,Ana Carolina Squeff de Callegaro,Dagoberto Lana-Peixoto,Marco Aurélio |
author_role |
author |
author2 |
Becker,Jefferson Varela,Daniel Lima Fröhlich,Alan Christmann Rech,Bruna Constantino Mattos,Ana Carolina Squeff de Callegaro,Dagoberto Lana-Peixoto,Marco Aurélio |
author2_role |
author author author author author author author |
dc.contributor.author.fl_str_mv |
Passos,Giordani Rodrigues dos Becker,Jefferson Varela,Daniel Lima Fröhlich,Alan Christmann Rech,Bruna Constantino Mattos,Ana Carolina Squeff de Callegaro,Dagoberto Lana-Peixoto,Marco Aurélio |
dc.subject.por.fl_str_mv |
Multiple Sclerosis Prevalence Epidemiology |
topic |
Multiple Sclerosis Prevalence Epidemiology |
description |
ABSTRACT Background: To improve the comparability of multiple sclerosis (MS) prevalence across Brazilian regions, the Brazilian Committee for Treatment and Research in MS has implemented a standardized approach to assess the prevalence of the disease in five key cities, which were deemed representative of their regions in terms of socio-geographical features and where in-person revision of each case was feasible. Objective: To report the point-prevalence of MS in Passo Fundo, one of the key cities in Southern Brazil. Methods: We sought to identify all MS patients who were living in Passo Fundo on July 1st, 2015. The primary source for case ascertainment was records from the offices of neurologists and neurosurgeons practicing in the city. Multiple secondary sources were used to maximize identification of cases. All patients underwent in-person review of the diagnosis by a panel of neurologists with experience in MS. Results: We identified 52 MS patients living in Passo Fundo on July 1st, 2015. The point-prevalence rate for MS was 26.4/100,000 population (95% confidence interval, 19.7 to 34.6/100,000). Among the MS cases, 42 (80.8%) were female, for a sex ratio of 4.2:1. Forty-six cases (88.5%) were categorized as relapsing-remitting MS, and the remaining 6 cases, as secondary progressive MS (11.5%). Other epidemiological and clinical features were comparable to national and international MS populations. Conclusions: The prevalence of MS in Passo Fundo is one of the highest reported in Brazil so far. Studies in other key Brazilian cities, using the same methodology, are currently being carried out. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-08-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2021000800692 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2021000800692 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/0004-282x-anp-2020-0221 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Academia Brasileira de Neurologia - ABNEURO |
publisher.none.fl_str_mv |
Academia Brasileira de Neurologia - ABNEURO |
dc.source.none.fl_str_mv |
Arquivos de Neuro-Psiquiatria v.79 n.8 2021 reponame:Arquivos de neuro-psiquiatria (Online) instname:Academia Brasileira de Neurologia instacron:ABNEURO |
instname_str |
Academia Brasileira de Neurologia |
instacron_str |
ABNEURO |
institution |
ABNEURO |
reponame_str |
Arquivos de neuro-psiquiatria (Online) |
collection |
Arquivos de neuro-psiquiatria (Online) |
repository.name.fl_str_mv |
Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologia |
repository.mail.fl_str_mv |
||revista.arquivos@abneuro.org |
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