Management of primary spinal chondrosarcoma: report of two cases causing cord compression
Autor(a) principal: | |
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Data de Publicação: | 2004 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Arquivos de neuro-psiquiatria (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2004000500026 |
Resumo: | Chondrosarcomas are malignant tumors that rarely grow inside the spinal canal. Prognosis depends on histological features, patient's age and surgical margins free from tumor. Response to radio and chemotherapy is poor. Ideal treatment consists of total " en-block" resection, not always achievable due to limitation of location, compromise of stability and risk of inducing neurological deficits. Two cases of spinal chondrosarcoma causing cord compression are reported, located in the cervical and thoracic spine. Microsurgical technique consisted of initial debulking followed by removal of margins until limits free from tumor were obtained. Total resection was accomplished and neurological function improved in both cases. Follow-up has been seven and one year respectively, with no evidence of recurrence and preserved neurological functions. Association between chondrosarcoma and estrogen-dependent tumor has been confirmed in this report. Although " en-block" resection of a chondrosarcoma should be tried whenever possible, tumor fragmentation should be considered in difficult cases, as in the present report, in which a long period free from recurrence with good quality of life can be obtained. |
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Management of primary spinal chondrosarcoma: report of two cases causing cord compressionchondrosarcomaspinal neoplasmsspinal cord compressionmicrosurgeryChondrosarcomas are malignant tumors that rarely grow inside the spinal canal. Prognosis depends on histological features, patient's age and surgical margins free from tumor. Response to radio and chemotherapy is poor. Ideal treatment consists of total " en-block" resection, not always achievable due to limitation of location, compromise of stability and risk of inducing neurological deficits. Two cases of spinal chondrosarcoma causing cord compression are reported, located in the cervical and thoracic spine. Microsurgical technique consisted of initial debulking followed by removal of margins until limits free from tumor were obtained. Total resection was accomplished and neurological function improved in both cases. Follow-up has been seven and one year respectively, with no evidence of recurrence and preserved neurological functions. Association between chondrosarcoma and estrogen-dependent tumor has been confirmed in this report. Although " en-block" resection of a chondrosarcoma should be tried whenever possible, tumor fragmentation should be considered in difficult cases, as in the present report, in which a long period free from recurrence with good quality of life can be obtained.Academia Brasileira de Neurologia - ABNEURO2004-09-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2004000500026Arquivos de Neuro-Psiquiatria v.62 n.3b 2004reponame:Arquivos de neuro-psiquiatria (Online)instname:Academia Brasileira de Neurologiainstacron:ABNEURO10.1590/S0004-282X2004000500026info:eu-repo/semantics/openAccessPrevedello,Daniel Monte-SerratCordeiro,Joacir GraciolliKoerbel,AndreiDitzel,Léo Fernando da SilvaAraújo,João Cândidoeng2004-10-05T00:00:00Zoai:scielo:S0004-282X2004000500026Revistahttp://www.scielo.br/anphttps://old.scielo.br/oai/scielo-oai.php||revista.arquivos@abneuro.org1678-42270004-282Xopendoar:2004-10-05T00:00Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologiafalse |
dc.title.none.fl_str_mv |
Management of primary spinal chondrosarcoma: report of two cases causing cord compression |
title |
Management of primary spinal chondrosarcoma: report of two cases causing cord compression |
spellingShingle |
Management of primary spinal chondrosarcoma: report of two cases causing cord compression Prevedello,Daniel Monte-Serrat chondrosarcoma spinal neoplasms spinal cord compression microsurgery |
title_short |
Management of primary spinal chondrosarcoma: report of two cases causing cord compression |
title_full |
Management of primary spinal chondrosarcoma: report of two cases causing cord compression |
title_fullStr |
Management of primary spinal chondrosarcoma: report of two cases causing cord compression |
title_full_unstemmed |
Management of primary spinal chondrosarcoma: report of two cases causing cord compression |
title_sort |
Management of primary spinal chondrosarcoma: report of two cases causing cord compression |
author |
Prevedello,Daniel Monte-Serrat |
author_facet |
Prevedello,Daniel Monte-Serrat Cordeiro,Joacir Graciolli Koerbel,Andrei Ditzel,Léo Fernando da Silva Araújo,João Cândido |
author_role |
author |
author2 |
Cordeiro,Joacir Graciolli Koerbel,Andrei Ditzel,Léo Fernando da Silva Araújo,João Cândido |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Prevedello,Daniel Monte-Serrat Cordeiro,Joacir Graciolli Koerbel,Andrei Ditzel,Léo Fernando da Silva Araújo,João Cândido |
dc.subject.por.fl_str_mv |
chondrosarcoma spinal neoplasms spinal cord compression microsurgery |
topic |
chondrosarcoma spinal neoplasms spinal cord compression microsurgery |
description |
Chondrosarcomas are malignant tumors that rarely grow inside the spinal canal. Prognosis depends on histological features, patient's age and surgical margins free from tumor. Response to radio and chemotherapy is poor. Ideal treatment consists of total " en-block" resection, not always achievable due to limitation of location, compromise of stability and risk of inducing neurological deficits. Two cases of spinal chondrosarcoma causing cord compression are reported, located in the cervical and thoracic spine. Microsurgical technique consisted of initial debulking followed by removal of margins until limits free from tumor were obtained. Total resection was accomplished and neurological function improved in both cases. Follow-up has been seven and one year respectively, with no evidence of recurrence and preserved neurological functions. Association between chondrosarcoma and estrogen-dependent tumor has been confirmed in this report. Although " en-block" resection of a chondrosarcoma should be tried whenever possible, tumor fragmentation should be considered in difficult cases, as in the present report, in which a long period free from recurrence with good quality of life can be obtained. |
publishDate |
2004 |
dc.date.none.fl_str_mv |
2004-09-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2004000500026 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2004000500026 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S0004-282X2004000500026 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Academia Brasileira de Neurologia - ABNEURO |
publisher.none.fl_str_mv |
Academia Brasileira de Neurologia - ABNEURO |
dc.source.none.fl_str_mv |
Arquivos de Neuro-Psiquiatria v.62 n.3b 2004 reponame:Arquivos de neuro-psiquiatria (Online) instname:Academia Brasileira de Neurologia instacron:ABNEURO |
instname_str |
Academia Brasileira de Neurologia |
instacron_str |
ABNEURO |
institution |
ABNEURO |
reponame_str |
Arquivos de neuro-psiquiatria (Online) |
collection |
Arquivos de neuro-psiquiatria (Online) |
repository.name.fl_str_mv |
Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologia |
repository.mail.fl_str_mv |
||revista.arquivos@abneuro.org |
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1754212757423521792 |