Cervical arterial dissection: clinical characteristics in a neurology service in São Paulo, Brazil

Detalhes bibliográficos
Autor(a) principal: Reges,Danyelle Sadala
Data de Publicação: 2019
Outros Autores: Mazzeo,Marcela, Rosalino,Rafael, Gagliardi,Vivian Dias Baptista, Cerqueira,Leandro Gama, Gagliardi,Rubens José
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Arquivos de neuro-psiquiatria (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2019000900632
Resumo: ABSTRACT Cervical arterial dissection accounts for only a small proportion of ischemic stroke but arouses scientific interest due to its wide clinical variability. Objective: This study aimed to evaluate its risk factors, outline its clinical characteristics, compare treatment with antiaggregation or anticoagulation, and explore the prognosis of patients with cervical arterial dissection. Methods: An observational, retrospective study using data from medical records on patients with cervical arterial dissection between January 2010 and August 2015. Results: The total number of patients was 41. The patients' ages ranged from 19 to 75 years, with an average of 44.5 years. The most common risk factor was smoking. Antiaggregation was used in the majority of patients (65.5%); 43% of all patients recanalized in six months, more frequently in patients who had received anticoagulation (p = 0.04). Conclusion: The presence of atherosclerotic disease is considered rare in patients with cervical arterial dissection; however, our study found a high frequency of hypertension, smoking and dyslipidemia. The choice of antithrombotic remains controversial and will depend on the judgment of the medical professional; the clinical results with anticoagulation or antiaggregation were similar but there was more recanalization in the group treated with anticoagulation; its course was favorable in both situations. The recurrence of cervical arterial dissection and stroke is considered a rare event and its course is favorable.
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spelling Cervical arterial dissection: clinical characteristics in a neurology service in São Paulo, BrazilStrokerisk factorsprimary preventionsecondary preventionanticoagulantsABSTRACT Cervical arterial dissection accounts for only a small proportion of ischemic stroke but arouses scientific interest due to its wide clinical variability. Objective: This study aimed to evaluate its risk factors, outline its clinical characteristics, compare treatment with antiaggregation or anticoagulation, and explore the prognosis of patients with cervical arterial dissection. Methods: An observational, retrospective study using data from medical records on patients with cervical arterial dissection between January 2010 and August 2015. Results: The total number of patients was 41. The patients' ages ranged from 19 to 75 years, with an average of 44.5 years. The most common risk factor was smoking. Antiaggregation was used in the majority of patients (65.5%); 43% of all patients recanalized in six months, more frequently in patients who had received anticoagulation (p = 0.04). Conclusion: The presence of atherosclerotic disease is considered rare in patients with cervical arterial dissection; however, our study found a high frequency of hypertension, smoking and dyslipidemia. The choice of antithrombotic remains controversial and will depend on the judgment of the medical professional; the clinical results with anticoagulation or antiaggregation were similar but there was more recanalization in the group treated with anticoagulation; its course was favorable in both situations. The recurrence of cervical arterial dissection and stroke is considered a rare event and its course is favorable.Academia Brasileira de Neurologia - ABNEURO2019-09-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2019000900632Arquivos de Neuro-Psiquiatria v.77 n.9 2019reponame:Arquivos de neuro-psiquiatria (Online)instname:Academia Brasileira de Neurologiainstacron:ABNEURO10.1590/0004-282x20190108info:eu-repo/semantics/openAccessReges,Danyelle SadalaMazzeo,MarcelaRosalino,RafaelGagliardi,Vivian Dias BaptistaCerqueira,Leandro GamaGagliardi,Rubens Joséeng2019-09-19T00:00:00Zoai:scielo:S0004-282X2019000900632Revistahttp://www.scielo.br/anphttps://old.scielo.br/oai/scielo-oai.php||revista.arquivos@abneuro.org1678-42270004-282Xopendoar:2019-09-19T00:00Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologiafalse
dc.title.none.fl_str_mv Cervical arterial dissection: clinical characteristics in a neurology service in São Paulo, Brazil
title Cervical arterial dissection: clinical characteristics in a neurology service in São Paulo, Brazil
spellingShingle Cervical arterial dissection: clinical characteristics in a neurology service in São Paulo, Brazil
Reges,Danyelle Sadala
Stroke
risk factors
primary prevention
secondary prevention
anticoagulants
title_short Cervical arterial dissection: clinical characteristics in a neurology service in São Paulo, Brazil
title_full Cervical arterial dissection: clinical characteristics in a neurology service in São Paulo, Brazil
title_fullStr Cervical arterial dissection: clinical characteristics in a neurology service in São Paulo, Brazil
title_full_unstemmed Cervical arterial dissection: clinical characteristics in a neurology service in São Paulo, Brazil
title_sort Cervical arterial dissection: clinical characteristics in a neurology service in São Paulo, Brazil
author Reges,Danyelle Sadala
author_facet Reges,Danyelle Sadala
Mazzeo,Marcela
Rosalino,Rafael
Gagliardi,Vivian Dias Baptista
Cerqueira,Leandro Gama
Gagliardi,Rubens José
author_role author
author2 Mazzeo,Marcela
Rosalino,Rafael
Gagliardi,Vivian Dias Baptista
Cerqueira,Leandro Gama
Gagliardi,Rubens José
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Reges,Danyelle Sadala
Mazzeo,Marcela
Rosalino,Rafael
Gagliardi,Vivian Dias Baptista
Cerqueira,Leandro Gama
Gagliardi,Rubens José
dc.subject.por.fl_str_mv Stroke
risk factors
primary prevention
secondary prevention
anticoagulants
topic Stroke
risk factors
primary prevention
secondary prevention
anticoagulants
description ABSTRACT Cervical arterial dissection accounts for only a small proportion of ischemic stroke but arouses scientific interest due to its wide clinical variability. Objective: This study aimed to evaluate its risk factors, outline its clinical characteristics, compare treatment with antiaggregation or anticoagulation, and explore the prognosis of patients with cervical arterial dissection. Methods: An observational, retrospective study using data from medical records on patients with cervical arterial dissection between January 2010 and August 2015. Results: The total number of patients was 41. The patients' ages ranged from 19 to 75 years, with an average of 44.5 years. The most common risk factor was smoking. Antiaggregation was used in the majority of patients (65.5%); 43% of all patients recanalized in six months, more frequently in patients who had received anticoagulation (p = 0.04). Conclusion: The presence of atherosclerotic disease is considered rare in patients with cervical arterial dissection; however, our study found a high frequency of hypertension, smoking and dyslipidemia. The choice of antithrombotic remains controversial and will depend on the judgment of the medical professional; the clinical results with anticoagulation or antiaggregation were similar but there was more recanalization in the group treated with anticoagulation; its course was favorable in both situations. The recurrence of cervical arterial dissection and stroke is considered a rare event and its course is favorable.
publishDate 2019
dc.date.none.fl_str_mv 2019-09-01
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dc.language.iso.fl_str_mv eng
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dc.relation.none.fl_str_mv 10.1590/0004-282x20190108
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dc.publisher.none.fl_str_mv Academia Brasileira de Neurologia - ABNEURO
publisher.none.fl_str_mv Academia Brasileira de Neurologia - ABNEURO
dc.source.none.fl_str_mv Arquivos de Neuro-Psiquiatria v.77 n.9 2019
reponame:Arquivos de neuro-psiquiatria (Online)
instname:Academia Brasileira de Neurologia
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reponame_str Arquivos de neuro-psiquiatria (Online)
collection Arquivos de neuro-psiquiatria (Online)
repository.name.fl_str_mv Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologia
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