The role of surgery in primary central nervous system lymphomas

Detalhes bibliográficos
Autor(a) principal: Villalonga,Juan Francisco
Data de Publicação: 2018
Outros Autores: Alessandro,Lucas, Farez,Mauricio Franco, Mormandi,Rubén, Cervio,Andrés, Alcorta,Santiago Condomí, Muggeri,Alejandro
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Arquivos de neuro-psiquiatria (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2018000300139
Resumo: ABSTRACT Background Primary central nervous system lymphomas (PCNSL) are infrequent. The traditional treatment of choice is chemotherapy. Complete resections have generally not been recommended, because of the risk of permanent central nervous system deficits with no proven improvement in survival. The aim of the current study was to compare survival among patients with PCNSL who underwent biopsy versus surgical resection. Methods A retrospective study was conducted on 50 patients with a confirmed diagnosis of PCNSL treated at our center from January 1994 to July 2015. Results Patients in the resection group exhibited significantly longer median survival time, relative to the biopsy group, surviving a median 31 months versus 14.5 months; p = 0.016. Conclusions In our series, patients who had surgical resection of their tumor survived a median 16.5 months longer than patients who underwent biopsy alone.
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spelling The role of surgery in primary central nervous system lymphomaslymphomatherapeuticsbiopsysurvivalABSTRACT Background Primary central nervous system lymphomas (PCNSL) are infrequent. The traditional treatment of choice is chemotherapy. Complete resections have generally not been recommended, because of the risk of permanent central nervous system deficits with no proven improvement in survival. The aim of the current study was to compare survival among patients with PCNSL who underwent biopsy versus surgical resection. Methods A retrospective study was conducted on 50 patients with a confirmed diagnosis of PCNSL treated at our center from January 1994 to July 2015. Results Patients in the resection group exhibited significantly longer median survival time, relative to the biopsy group, surviving a median 31 months versus 14.5 months; p = 0.016. Conclusions In our series, patients who had surgical resection of their tumor survived a median 16.5 months longer than patients who underwent biopsy alone.Academia Brasileira de Neurologia - ABNEURO2018-03-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2018000300139Arquivos de Neuro-Psiquiatria v.76 n.3 2018reponame:Arquivos de neuro-psiquiatria (Online)instname:Academia Brasileira de Neurologiainstacron:ABNEURO10.1590/0004-282x20180002info:eu-repo/semantics/openAccessVillalonga,Juan FranciscoAlessandro,LucasFarez,Mauricio FrancoMormandi,RubénCervio,AndrésAlcorta,Santiago CondomíMuggeri,Alejandroeng2018-06-26T00:00:00Zoai:scielo:S0004-282X2018000300139Revistahttp://www.scielo.br/anphttps://old.scielo.br/oai/scielo-oai.php||revista.arquivos@abneuro.org1678-42270004-282Xopendoar:2018-06-26T00:00Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologiafalse
dc.title.none.fl_str_mv The role of surgery in primary central nervous system lymphomas
title The role of surgery in primary central nervous system lymphomas
spellingShingle The role of surgery in primary central nervous system lymphomas
Villalonga,Juan Francisco
lymphoma
therapeutics
biopsy
survival
title_short The role of surgery in primary central nervous system lymphomas
title_full The role of surgery in primary central nervous system lymphomas
title_fullStr The role of surgery in primary central nervous system lymphomas
title_full_unstemmed The role of surgery in primary central nervous system lymphomas
title_sort The role of surgery in primary central nervous system lymphomas
author Villalonga,Juan Francisco
author_facet Villalonga,Juan Francisco
Alessandro,Lucas
Farez,Mauricio Franco
Mormandi,Rubén
Cervio,Andrés
Alcorta,Santiago Condomí
Muggeri,Alejandro
author_role author
author2 Alessandro,Lucas
Farez,Mauricio Franco
Mormandi,Rubén
Cervio,Andrés
Alcorta,Santiago Condomí
Muggeri,Alejandro
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Villalonga,Juan Francisco
Alessandro,Lucas
Farez,Mauricio Franco
Mormandi,Rubén
Cervio,Andrés
Alcorta,Santiago Condomí
Muggeri,Alejandro
dc.subject.por.fl_str_mv lymphoma
therapeutics
biopsy
survival
topic lymphoma
therapeutics
biopsy
survival
description ABSTRACT Background Primary central nervous system lymphomas (PCNSL) are infrequent. The traditional treatment of choice is chemotherapy. Complete resections have generally not been recommended, because of the risk of permanent central nervous system deficits with no proven improvement in survival. The aim of the current study was to compare survival among patients with PCNSL who underwent biopsy versus surgical resection. Methods A retrospective study was conducted on 50 patients with a confirmed diagnosis of PCNSL treated at our center from January 1994 to July 2015. Results Patients in the resection group exhibited significantly longer median survival time, relative to the biopsy group, surviving a median 31 months versus 14.5 months; p = 0.016. Conclusions In our series, patients who had surgical resection of their tumor survived a median 16.5 months longer than patients who underwent biopsy alone.
publishDate 2018
dc.date.none.fl_str_mv 2018-03-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2018000300139
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2018000300139
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/0004-282x20180002
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Academia Brasileira de Neurologia - ABNEURO
publisher.none.fl_str_mv Academia Brasileira de Neurologia - ABNEURO
dc.source.none.fl_str_mv Arquivos de Neuro-Psiquiatria v.76 n.3 2018
reponame:Arquivos de neuro-psiquiatria (Online)
instname:Academia Brasileira de Neurologia
instacron:ABNEURO
instname_str Academia Brasileira de Neurologia
instacron_str ABNEURO
institution ABNEURO
reponame_str Arquivos de neuro-psiquiatria (Online)
collection Arquivos de neuro-psiquiatria (Online)
repository.name.fl_str_mv Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologia
repository.mail.fl_str_mv ||revista.arquivos@abneuro.org
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