Partial laryngectomy in glottic cancer: complications and oncological results

• Main Author: Graciano,Agnaldo José
• Publication Date: 2016
• Other Authors: Sonagli,Marina, Silva,Ana Gabriela Clemente da, Fischer,Carlos Augusto, Chone,Carlos Takahiro
• Format: Article
• Language: eng
• Source: Brazilian Journal of Otorhinolaryngology
• Download full: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1808-86942016000300275
• topic: Carcinoma; Larynx; Laryngectomy; Radiotherapy

ABSTRACT INTRODUCTION: Most patients with laryngeal carcinoma present tumors in the glottis that can be treated by different treatment modalities. Some authors consider open partial laryngectomy as obsolete, while others still deem this as a viable and cost-efficient option. OBJECTIVES: To compare the oncological and functional results of a series of patients undergoing partial laryngectomy vs. external radiotherapy for the treatment of glottic cancer. METHODS: Historical cohort study with a series of glottic carcinoma patients undergoing partial laryngectomy or external radiotherapy during a period of ten years. RESULTS: Sixty-two patients with glottic carcinoma were included. Group A comprised those submitted to partial laryngectomy (n = 30), and Group B, those who underwent radiotherapy (n = 32). They were homogeneous in the comparison of mean age, 56.4 vs. 60.4 years (p = 0.12) and distribution in pathological stage (p = 0.91). With regard to oncological outcome, there were no differences in distant metastasis rates, or second primary tumor between groups (p = 1.0), as well as in disease-free time, laryngeal rescue-free time, and overall five-year survival. Severe complication rates were also similar between groups. CONCLUSION: Open partial laryngectomy had complication rates and oncological results similar to those of radiotherapy for patients with glottic carcinomas and should still be considered among the main available therapeutic options.