Particularities of the use of injectables reducing localized facial fat
Autor(a) principal: | |
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Data de Publicação: | 2021 |
Outros Autores: | , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Aesthetic Orofacial Science |
Texto Completo: | https://ahof.emnuvens.com.br/ahof/article/view/43 |
Resumo: | Objective: to evaluate the particularities of the use of injectables in the reduction of localized facial fat, focusing on deoxycholic acid and sodium deoxycholate, in order to analyze its efficacy and present relevant information for clinical practice. Bibliographic Review: The compounds that promote lipoclasis, deoxycholic acid and sodium deoxycholate have been used in injectable treatments to decrease fat deposits located on the face. Deoxycholic acid is a synthetic bile acid recently introduced in the field of rejuvenating therapies for the reduction of submental fat. Sodium deoxycholate is the salt of deoxycholic acid, has a detergent action and solubilizes cell membranes, induces tissue necrosis and volume reduction. Most of the studies evaluated dealt with the adiposity of the submental region, however treatments were also reported in the infrapalpebral, mandibular regions and in the regions of the middle and lower third of the face. It was observed that both substances are effective and safe, produce satisfactory results and cause slight and local adverse reactions. Conclusion: The reduction of localized fat in the face through the injection of sodium deoxycholate or deoxycholic acid has a unique action in the treatment of localized fat for inducing adipocyte necrosis and neocolagenesis. |
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Particularities of the use of injectables reducing localized facial fat Particularidades del uso de inyectables en la reducción de grasa facialParticularidades do uso de injetáveis na redução de gordura localizada na facemesotherapyrejuvenationdeoxycholic acidsodium deoxycholate.lipoclasiamesoterapiarejuvenescimentoácido desoxicólicodesoxicolato de sódio.ipmesoterapiarejuvenecimientoácido desoxicólicodesoxicolato de sodioObjective: to evaluate the particularities of the use of injectables in the reduction of localized facial fat, focusing on deoxycholic acid and sodium deoxycholate, in order to analyze its efficacy and present relevant information for clinical practice. Bibliographic Review: The compounds that promote lipoclasis, deoxycholic acid and sodium deoxycholate have been used in injectable treatments to decrease fat deposits located on the face. Deoxycholic acid is a synthetic bile acid recently introduced in the field of rejuvenating therapies for the reduction of submental fat. Sodium deoxycholate is the salt of deoxycholic acid, has a detergent action and solubilizes cell membranes, induces tissue necrosis and volume reduction. Most of the studies evaluated dealt with the adiposity of the submental region, however treatments were also reported in the infrapalpebral, mandibular regions and in the regions of the middle and lower third of the face. It was observed that both substances are effective and safe, produce satisfactory results and cause slight and local adverse reactions. Conclusion: The reduction of localized fat in the face through the injection of sodium deoxycholate or deoxycholic acid has a unique action in the treatment of localized fat for inducing adipocyte necrosis and neocolagenesis.Objetivo: evaluar las particularidades del uso de inyectables en la reducción de la grasa facial localizada, centrándose en el ácido desoxicólico y el desoxicolato de sodio, con el fin de analizar su eficacia y presentar información relevante para la práctica clínica. Revisión bibliográfica: Los compuestos que favorecen la lipoclasis, el ácido desoxicólico y el desoxicolato de sodio se han utilizado en tratamientos inyectables para disminuir los depósitos de grasa localizada en el rostro. El ácido desoxicólico es un ácido biliar sintético introducido recientemente en el campo de las terapias rejuvenecedoras para la reducción de la grasa submentoniana. El desoxicolato de sodio es la sal del ácido desoxicólico, tiene acción detergente y solubiliza las membranas celulares, induce necrosis tisular y reducción de volumen. La mayoría de los estudios evaluados versaron sobre la adiposidad de la región submentoniana, sin embargo, también se reportaron tratamientos en las regiones infrapalpebral, mandibular y en las regiones del tercio medio e inferior de la cara. Se observó que ambas sustancias son eficaces y seguras, producen resultados satisfactorios y provocan reacciones adversas leves y locales. Conclusión: La reducción de la grasa localizada en el rostro mediante la inyección de desoxicolato de sodio o ácido desoxicólico tiene una acción favorable en el tratamiento de la grasa localizada para inducir la necrosis y neocolagénesis de los adipocitos.Objetivo: avaliar as particularidades do uso de injetáveis na redução de gordura localizada facial, com foco no ácido desoxicólico e desoxicolato de sódio, com intuito de analisar sua eficácia e apresentar informações relevantes para a prática clínica. Revisão Bibliográfica: Os compostos que promovem lipoclasia, ácido desoxicólico e desoxicolato de sódio têm sido usados em tratamentos injetáveis para diminuição de depósitos de gordura localizados na face. O ácido desoxicólico é um ácido biliar sintético recentemente introduzido no âmbito das terapias em rejuvenescimento para a redução da gordura submentoniana. O desoxicolato de sódio é o sal do ácido desoxicólico, possui ação detergente e solubiliza as membranas celulares, induz necrose tecidual e redução do volume. A maioria dos estudos avaliados tratou a adiposidade da região submental, no entanto também foram relatados tratamentos nas regiões infrapalpebrais, mandibulares e nas regiões de terço médio e inferior de face. Observou-se que ambos as substâncias são eficazes e seguras, produzem resultados satisfatórios e causam reações adversas leves e locais. Conclusão: A redução de gordura localizada na face através da injeção de desoxicolato de sódio ou ácido desoxicólico possui uma ação singular no tratamento da gordura localizada por induzir a necrose dos adipócitos e neocolagênese.Profa. Dra. Daniela Martins de Souza2021-03-15info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionArtigo avaliado pelos Paresapplication/pdfhttps://ahof.emnuvens.com.br/ahof/article/view/4310.51670/ahof.v2i1.43Aesthetic Orofacial Science; v. 2 n. 1 (2021): Harmonização Orofacial - Uma Visão Integrativa da HOF.; 49-602675-7311reponame:Aesthetic Orofacial Scienceinstname:Associação Brasileira de Harmonização Orofacial (ABRAHOF)instacron:ABRAHOFporhttps://ahof.emnuvens.com.br/ahof/article/view/43/48Pereira, Idalina Marcia Guedes, Ruy Magalhães, Mariana de Azevedo info:eu-repo/semantics/openAccess2024-03-11T00:04:57Zoai:ojs.ahof.emnuvens.com.br:article/43Revistahttps://ahof.emnuvens.com.br/ahofONGhttps://ahof.emnuvens.com.br/ahof/oaimagazine@abrahof.org.br ||10.516702675-73112675-7311opendoar:2024-03-11T00:04:57Aesthetic Orofacial Science - Associação Brasileira de Harmonização Orofacial (ABRAHOF)false |
dc.title.none.fl_str_mv |
Particularities of the use of injectables reducing localized facial fat Particularidades del uso de inyectables en la reducción de grasa facial Particularidades do uso de injetáveis na redução de gordura localizada na face |
title |
Particularities of the use of injectables reducing localized facial fat |
spellingShingle |
Particularities of the use of injectables reducing localized facial fat Pereira, Idalina Marcia mesotherapy rejuvenation deoxycholic acid sodium deoxycholate. lipoclasia mesoterapia rejuvenescimento ácido desoxicólico desoxicolato de sódio. ip mesoterapia rejuvenecimiento ácido desoxicólico desoxicolato de sodio |
title_short |
Particularities of the use of injectables reducing localized facial fat |
title_full |
Particularities of the use of injectables reducing localized facial fat |
title_fullStr |
Particularities of the use of injectables reducing localized facial fat |
title_full_unstemmed |
Particularities of the use of injectables reducing localized facial fat |
title_sort |
Particularities of the use of injectables reducing localized facial fat |
author |
Pereira, Idalina Marcia |
author_facet |
Pereira, Idalina Marcia Guedes, Ruy Magalhães, Mariana de Azevedo |
author_role |
author |
author2 |
Guedes, Ruy Magalhães, Mariana de Azevedo |
author2_role |
author author |
dc.contributor.author.fl_str_mv |
Pereira, Idalina Marcia Guedes, Ruy Magalhães, Mariana de Azevedo |
dc.subject.por.fl_str_mv |
mesotherapy rejuvenation deoxycholic acid sodium deoxycholate. lipoclasia mesoterapia rejuvenescimento ácido desoxicólico desoxicolato de sódio. ip mesoterapia rejuvenecimiento ácido desoxicólico desoxicolato de sodio |
topic |
mesotherapy rejuvenation deoxycholic acid sodium deoxycholate. lipoclasia mesoterapia rejuvenescimento ácido desoxicólico desoxicolato de sódio. ip mesoterapia rejuvenecimiento ácido desoxicólico desoxicolato de sodio |
description |
Objective: to evaluate the particularities of the use of injectables in the reduction of localized facial fat, focusing on deoxycholic acid and sodium deoxycholate, in order to analyze its efficacy and present relevant information for clinical practice. Bibliographic Review: The compounds that promote lipoclasis, deoxycholic acid and sodium deoxycholate have been used in injectable treatments to decrease fat deposits located on the face. Deoxycholic acid is a synthetic bile acid recently introduced in the field of rejuvenating therapies for the reduction of submental fat. Sodium deoxycholate is the salt of deoxycholic acid, has a detergent action and solubilizes cell membranes, induces tissue necrosis and volume reduction. Most of the studies evaluated dealt with the adiposity of the submental region, however treatments were also reported in the infrapalpebral, mandibular regions and in the regions of the middle and lower third of the face. It was observed that both substances are effective and safe, produce satisfactory results and cause slight and local adverse reactions. Conclusion: The reduction of localized fat in the face through the injection of sodium deoxycholate or deoxycholic acid has a unique action in the treatment of localized fat for inducing adipocyte necrosis and neocolagenesis. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-03-15 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Artigo avaliado pelos Pares |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://ahof.emnuvens.com.br/ahof/article/view/43 10.51670/ahof.v2i1.43 |
url |
https://ahof.emnuvens.com.br/ahof/article/view/43 |
identifier_str_mv |
10.51670/ahof.v2i1.43 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://ahof.emnuvens.com.br/ahof/article/view/43/48 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Profa. Dra. Daniela Martins de Souza |
publisher.none.fl_str_mv |
Profa. Dra. Daniela Martins de Souza |
dc.source.none.fl_str_mv |
Aesthetic Orofacial Science; v. 2 n. 1 (2021): Harmonização Orofacial - Uma Visão Integrativa da HOF.; 49-60 2675-7311 reponame:Aesthetic Orofacial Science instname:Associação Brasileira de Harmonização Orofacial (ABRAHOF) instacron:ABRAHOF |
instname_str |
Associação Brasileira de Harmonização Orofacial (ABRAHOF) |
instacron_str |
ABRAHOF |
institution |
ABRAHOF |
reponame_str |
Aesthetic Orofacial Science |
collection |
Aesthetic Orofacial Science |
repository.name.fl_str_mv |
Aesthetic Orofacial Science - Associação Brasileira de Harmonização Orofacial (ABRAHOF) |
repository.mail.fl_str_mv |
magazine@abrahof.org.br || |
_version_ |
1797042116730290176 |