An interdisciplinary approach aiding the diagnosis of primary progressive aphasia: A case report

Detalhes bibliográficos
Autor(a) principal: Shigaeff,Nadia
Data de Publicação: 2017
Outros Autores: Zanetti,Mayra, Tierno,Sibelle de Almeida, Tommaso,Ana Beatriz Galhardi Di, Marques,Thais Cristina, Franco,Fábio Gazelato de Mello
Tipo de documento: Relatório
Idioma: eng
Título da fonte: Dementia & Neuropsychologia
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1980-57642017000100100
Resumo: ABSTRACT Frontotemporal dementia (FTD) is one of the most common causes of early-onset dementia with primary progressive aphasia (PPA) being the second-most-frequent form of this degenerative disease. Despite the similarity with progressive dementia (especially in early stages of Alzheimer´s disease), three types of PPA can be differentiated: semantic, agrammatic and logopenic (subtype discussed in this study). To date, no medications have been shown to improve or stabilize cognitive deficits in patients with PPA. We report the case of a 62-year-old woman with difficulty naming objects and planning. An interdisciplinary evaluation, including imaging and lab exams, together with neuropsychological and personality assessments, confirmed that the patient had logopenic PPA on the basis of repetition difficulty, phonemic and semantic paraphasias and absence of agrammatism. The timing of the assessment in this case, along with the resources available and commitment of an integrated interdisciplinary team, allowed a differential diagnosis (from other classical dementias) to be reached.
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spelling An interdisciplinary approach aiding the diagnosis of primary progressive aphasia: A case reportaphasiaelderlyfrontotemporal dementiaprogressive primary aphasiaABSTRACT Frontotemporal dementia (FTD) is one of the most common causes of early-onset dementia with primary progressive aphasia (PPA) being the second-most-frequent form of this degenerative disease. Despite the similarity with progressive dementia (especially in early stages of Alzheimer´s disease), three types of PPA can be differentiated: semantic, agrammatic and logopenic (subtype discussed in this study). To date, no medications have been shown to improve or stabilize cognitive deficits in patients with PPA. We report the case of a 62-year-old woman with difficulty naming objects and planning. An interdisciplinary evaluation, including imaging and lab exams, together with neuropsychological and personality assessments, confirmed that the patient had logopenic PPA on the basis of repetition difficulty, phonemic and semantic paraphasias and absence of agrammatism. The timing of the assessment in this case, along with the resources available and commitment of an integrated interdisciplinary team, allowed a differential diagnosis (from other classical dementias) to be reached.Academia Brasileira de Neurologia, Departamento de Neurologia Cognitiva e Envelhecimento2017-03-01info:eu-repo/semantics/reportinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1980-57642017000100100Dementia & Neuropsychologia v.11 n.1 2017reponame:Dementia & Neuropsychologiainstname:Associação de Neurologia Cognitiva e do Comportamento (ANCC)instacron:ANCC10.1590/1980-57642016dn11-010014info:eu-repo/semantics/openAccessShigaeff,NadiaZanetti,MayraTierno,Sibelle de AlmeidaTommaso,Ana Beatriz Galhardi DiMarques,Thais CristinaFranco,Fábio Gazelato de Melloeng2017-04-05T00:00:00Zoai:scielo:S1980-57642017000100100Revistahttp://www.demneuropsy.com.br/ONGhttps://old.scielo.br/oai/scielo-oai.php||demneuropsy@uol.com.br1980-57641980-5764opendoar:2017-04-05T00:00Dementia & Neuropsychologia - Associação de Neurologia Cognitiva e do Comportamento (ANCC)false
dc.title.none.fl_str_mv An interdisciplinary approach aiding the diagnosis of primary progressive aphasia: A case report
title An interdisciplinary approach aiding the diagnosis of primary progressive aphasia: A case report
spellingShingle An interdisciplinary approach aiding the diagnosis of primary progressive aphasia: A case report
Shigaeff,Nadia
aphasia
elderly
frontotemporal dementia
progressive primary aphasia
title_short An interdisciplinary approach aiding the diagnosis of primary progressive aphasia: A case report
title_full An interdisciplinary approach aiding the diagnosis of primary progressive aphasia: A case report
title_fullStr An interdisciplinary approach aiding the diagnosis of primary progressive aphasia: A case report
title_full_unstemmed An interdisciplinary approach aiding the diagnosis of primary progressive aphasia: A case report
title_sort An interdisciplinary approach aiding the diagnosis of primary progressive aphasia: A case report
author Shigaeff,Nadia
author_facet Shigaeff,Nadia
Zanetti,Mayra
Tierno,Sibelle de Almeida
Tommaso,Ana Beatriz Galhardi Di
Marques,Thais Cristina
Franco,Fábio Gazelato de Mello
author_role author
author2 Zanetti,Mayra
Tierno,Sibelle de Almeida
Tommaso,Ana Beatriz Galhardi Di
Marques,Thais Cristina
Franco,Fábio Gazelato de Mello
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Shigaeff,Nadia
Zanetti,Mayra
Tierno,Sibelle de Almeida
Tommaso,Ana Beatriz Galhardi Di
Marques,Thais Cristina
Franco,Fábio Gazelato de Mello
dc.subject.por.fl_str_mv aphasia
elderly
frontotemporal dementia
progressive primary aphasia
topic aphasia
elderly
frontotemporal dementia
progressive primary aphasia
description ABSTRACT Frontotemporal dementia (FTD) is one of the most common causes of early-onset dementia with primary progressive aphasia (PPA) being the second-most-frequent form of this degenerative disease. Despite the similarity with progressive dementia (especially in early stages of Alzheimer´s disease), three types of PPA can be differentiated: semantic, agrammatic and logopenic (subtype discussed in this study). To date, no medications have been shown to improve or stabilize cognitive deficits in patients with PPA. We report the case of a 62-year-old woman with difficulty naming objects and planning. An interdisciplinary evaluation, including imaging and lab exams, together with neuropsychological and personality assessments, confirmed that the patient had logopenic PPA on the basis of repetition difficulty, phonemic and semantic paraphasias and absence of agrammatism. The timing of the assessment in this case, along with the resources available and commitment of an integrated interdisciplinary team, allowed a differential diagnosis (from other classical dementias) to be reached.
publishDate 2017
dc.date.none.fl_str_mv 2017-03-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/report
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format report
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dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1980-57642017000100100
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1980-57642017000100100
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/1980-57642016dn11-010014
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Academia Brasileira de Neurologia, Departamento de Neurologia Cognitiva e Envelhecimento
publisher.none.fl_str_mv Academia Brasileira de Neurologia, Departamento de Neurologia Cognitiva e Envelhecimento
dc.source.none.fl_str_mv Dementia & Neuropsychologia v.11 n.1 2017
reponame:Dementia & Neuropsychologia
instname:Associação de Neurologia Cognitiva e do Comportamento (ANCC)
instacron:ANCC
instname_str Associação de Neurologia Cognitiva e do Comportamento (ANCC)
instacron_str ANCC
institution ANCC
reponame_str Dementia & Neuropsychologia
collection Dementia & Neuropsychologia
repository.name.fl_str_mv Dementia & Neuropsychologia - Associação de Neurologia Cognitiva e do Comportamento (ANCC)
repository.mail.fl_str_mv ||demneuropsy@uol.com.br
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