Cryptococcoma mimicking a brain tumor in an immunocompetent patient: case report of an extremely rare presentation
Autor(a) principal: | |
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Data de Publicação: | 2018 |
Outros Autores: | , , , , |
Tipo de documento: | Relatório |
Idioma: | eng |
Título da fonte: | São Paulo medical journal (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31802018000500492 |
Resumo: | ABSTRACT CONTEXT: Central nervous system (CNS) infectious diseases have high prevalence in developing countries and their proper diagnosis and treatment are very important for public health planning. Cryptococcus neoformans is a fungus that may cause several CNS manifestations, especially in immunocompromised patients. Cryptococcal meningitis is the most common type of involvement. Mass-effect lesions are uncommon: they are described as cryptococcomas and their prevalence is even lower among immunocompetent patients. The aim here was to report an extremely rare case of cryptococcoma causing a mass effect and mimicking a brain tumor in an immunocompetent patient. The literature on CNS cryptococcal infections was reviewed with emphasis on cryptococcomas. Clinical, surgical and radiological data on a female patient with this rare presentation of cryptococcoma mimicking a brain tumor are described. Case Report: A 54-year-old female patient presented to the emergency department with a rapid-onset progressive history of confusion and completely dependency for basic activities. Neuroimaging showed a left occipital lesion and neurosurgical treatment was proposed. From histopathological evaluation, a diagnosis of cryptococcoma was established. She received clinical support with antifungals, but despite optimal clinical treatment, her condition evolved to death. CONCLUSIONS: Cryptococcal infections have several forms of presentation and, in immunocompetent patients, their manifestation may be even more different. Cryptococcoma is an extremely rare presentation in which proper surgical and clinical treatment should be instituted as quickly as possible, but even so, there is a high mortality rate. |
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Cryptococcoma mimicking a brain tumor in an immunocompetent patient: case report of an extremely rare presentationCryptococcosisBrain neoplasmsMeningitis, cryptococcalImmunocompetenceABSTRACT CONTEXT: Central nervous system (CNS) infectious diseases have high prevalence in developing countries and their proper diagnosis and treatment are very important for public health planning. Cryptococcus neoformans is a fungus that may cause several CNS manifestations, especially in immunocompromised patients. Cryptococcal meningitis is the most common type of involvement. Mass-effect lesions are uncommon: they are described as cryptococcomas and their prevalence is even lower among immunocompetent patients. The aim here was to report an extremely rare case of cryptococcoma causing a mass effect and mimicking a brain tumor in an immunocompetent patient. The literature on CNS cryptococcal infections was reviewed with emphasis on cryptococcomas. Clinical, surgical and radiological data on a female patient with this rare presentation of cryptococcoma mimicking a brain tumor are described. Case Report: A 54-year-old female patient presented to the emergency department with a rapid-onset progressive history of confusion and completely dependency for basic activities. Neuroimaging showed a left occipital lesion and neurosurgical treatment was proposed. From histopathological evaluation, a diagnosis of cryptococcoma was established. She received clinical support with antifungals, but despite optimal clinical treatment, her condition evolved to death. CONCLUSIONS: Cryptococcal infections have several forms of presentation and, in immunocompetent patients, their manifestation may be even more different. Cryptococcoma is an extremely rare presentation in which proper surgical and clinical treatment should be instituted as quickly as possible, but even so, there is a high mortality rate.Associação Paulista de Medicina - APM2018-10-01info:eu-repo/semantics/reportinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31802018000500492Sao Paulo Medical Journal v.136 n.5 2018reponame:São Paulo medical journal (Online)instname:Associação Paulista de Medicinainstacron:APM10.1590/1516-3180.2017.0046210417info:eu-repo/semantics/openAccessPaiva,Aline Lariessy CamposAguiar,Guilherme Brasileiro deLovato,Renan MaximilianZanetti,Arthus Vilar DeolindoPanagopoulos,Alexandros TheodorosVeiga,José Carlos Esteveseng2018-12-17T00:00:00Zoai:scielo:S1516-31802018000500492Revistahttp://www.scielo.br/spmjhttps://old.scielo.br/oai/scielo-oai.phprevistas@apm.org.br1806-94601516-3180opendoar:2018-12-17T00:00São Paulo medical journal (Online) - Associação Paulista de Medicinafalse |
dc.title.none.fl_str_mv |
Cryptococcoma mimicking a brain tumor in an immunocompetent patient: case report of an extremely rare presentation |
title |
Cryptococcoma mimicking a brain tumor in an immunocompetent patient: case report of an extremely rare presentation |
spellingShingle |
Cryptococcoma mimicking a brain tumor in an immunocompetent patient: case report of an extremely rare presentation Paiva,Aline Lariessy Campos Cryptococcosis Brain neoplasms Meningitis, cryptococcal Immunocompetence |
title_short |
Cryptococcoma mimicking a brain tumor in an immunocompetent patient: case report of an extremely rare presentation |
title_full |
Cryptococcoma mimicking a brain tumor in an immunocompetent patient: case report of an extremely rare presentation |
title_fullStr |
Cryptococcoma mimicking a brain tumor in an immunocompetent patient: case report of an extremely rare presentation |
title_full_unstemmed |
Cryptococcoma mimicking a brain tumor in an immunocompetent patient: case report of an extremely rare presentation |
title_sort |
Cryptococcoma mimicking a brain tumor in an immunocompetent patient: case report of an extremely rare presentation |
author |
Paiva,Aline Lariessy Campos |
author_facet |
Paiva,Aline Lariessy Campos Aguiar,Guilherme Brasileiro de Lovato,Renan Maximilian Zanetti,Arthus Vilar Deolindo Panagopoulos,Alexandros Theodoros Veiga,José Carlos Esteves |
author_role |
author |
author2 |
Aguiar,Guilherme Brasileiro de Lovato,Renan Maximilian Zanetti,Arthus Vilar Deolindo Panagopoulos,Alexandros Theodoros Veiga,José Carlos Esteves |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Paiva,Aline Lariessy Campos Aguiar,Guilherme Brasileiro de Lovato,Renan Maximilian Zanetti,Arthus Vilar Deolindo Panagopoulos,Alexandros Theodoros Veiga,José Carlos Esteves |
dc.subject.por.fl_str_mv |
Cryptococcosis Brain neoplasms Meningitis, cryptococcal Immunocompetence |
topic |
Cryptococcosis Brain neoplasms Meningitis, cryptococcal Immunocompetence |
description |
ABSTRACT CONTEXT: Central nervous system (CNS) infectious diseases have high prevalence in developing countries and their proper diagnosis and treatment are very important for public health planning. Cryptococcus neoformans is a fungus that may cause several CNS manifestations, especially in immunocompromised patients. Cryptococcal meningitis is the most common type of involvement. Mass-effect lesions are uncommon: they are described as cryptococcomas and their prevalence is even lower among immunocompetent patients. The aim here was to report an extremely rare case of cryptococcoma causing a mass effect and mimicking a brain tumor in an immunocompetent patient. The literature on CNS cryptococcal infections was reviewed with emphasis on cryptococcomas. Clinical, surgical and radiological data on a female patient with this rare presentation of cryptococcoma mimicking a brain tumor are described. Case Report: A 54-year-old female patient presented to the emergency department with a rapid-onset progressive history of confusion and completely dependency for basic activities. Neuroimaging showed a left occipital lesion and neurosurgical treatment was proposed. From histopathological evaluation, a diagnosis of cryptococcoma was established. She received clinical support with antifungals, but despite optimal clinical treatment, her condition evolved to death. CONCLUSIONS: Cryptococcal infections have several forms of presentation and, in immunocompetent patients, their manifestation may be even more different. Cryptococcoma is an extremely rare presentation in which proper surgical and clinical treatment should be instituted as quickly as possible, but even so, there is a high mortality rate. |
publishDate |
2018 |
dc.date.none.fl_str_mv |
2018-10-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/report |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
report |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31802018000500492 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31802018000500492 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/1516-3180.2017.0046210417 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Associação Paulista de Medicina - APM |
publisher.none.fl_str_mv |
Associação Paulista de Medicina - APM |
dc.source.none.fl_str_mv |
Sao Paulo Medical Journal v.136 n.5 2018 reponame:São Paulo medical journal (Online) instname:Associação Paulista de Medicina instacron:APM |
instname_str |
Associação Paulista de Medicina |
instacron_str |
APM |
institution |
APM |
reponame_str |
São Paulo medical journal (Online) |
collection |
São Paulo medical journal (Online) |
repository.name.fl_str_mv |
São Paulo medical journal (Online) - Associação Paulista de Medicina |
repository.mail.fl_str_mv |
revistas@apm.org.br |
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1754209266226429952 |