Hematological particularities and co-infections in injected drug users with AIDS

• Autor(a) principal: Brunetta,Denise Menezes
• Data de Publicação: 2013
• Outros Autores: De Santis,Gil Cunha, Vilar,Fernando Crivelenti, Brandão,Renata Amorim, Muniz,Renata Zomer de Albernaz, Lima,Geovana Momo Nogueira de, Amorelli-Chacel,Manuela Emiliana, Covas,Dimas Tadeu, Machado,Alcyone Artioli
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Brazilian Journal of Infectious Diseases
• Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702013000600005
• topic: AIDS; Injected drug use; Anemia; HCV; Mycobacteria

HIV patients infected through injected drug use have poorer prognosis than other groups. We evaluated the hematological alterations and rates of co-infections in injected drug use patients with AIDS. Injected drug use patients were younger, predominantly of male gender, and presented lower CD4, total lymphocyte, and platelet counts, but not neutrophil count, than control group. Injected drug use patients had a higher rate of hepatitis C and mycobacteria infection. Furthermore, all injected drug use patients with hemoglobin <10.0 g dL-1 and lymphocyte <1000 µL-1 had CD4 count lower than 100 µL-1. In conclusion, HIV-infected injected drug use patients constitute a special group of patients, and hemoglobin concentration and lymphocyte count can be used as surrogate markers for disease severity.