Virucidal PVP-copper salt composites against coronavirus produced by electrospinning and electrospraying
| Autor(a) principal: | |
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| Data de Publicação: | 2022 |
| Outros Autores: | , , , , , , |
| Tipo de documento: | Artigo |
| Título da fonte: | Repositório da Produção Científica e Intelectual da Unicamp |
| Texto Completo: | https://hdl.handle.net/20.500.12733/6182 |
Resumo: | Agradecimentos: All authors would like to thank Coordination for the Improvement of Higher Education Personnel (CAPES) (proc. 88881.505221/2020-01) for the financial support |
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Virucidal PVP-copper salt composites against coronavirus produced by electrospinning and electrosprayingEletrofiaçãoPovidonaCobreCoronavírusElectrospinningPolyvinylpyrrolidoneCopperCoronavirusesArtigo originalAgradecimentos: All authors would like to thank Coordination for the Improvement of Higher Education Personnel (CAPES) (proc. 88881.505221/2020-01) for the financial supportAbstract: Electrospinning technology was used to produced polyvinylpyrrolidone (PVP)-copper salt composites with structural differences, and their virucidal activity against coronavirus was investigated. The solutions were prepared with 20, 13.3, 10, and 6.6% w/v PVP containing 3, 1.0, 0.6, and 0.2% w/v Cu (II), respectively. The rheological properties and electrical conductivity contributing to the formation of the morphologies of the composite materials were observed by scanning electron microscopy (SEM). SEM images revealed the formation of electrospun PVP-copper salt ultrafine composite fibers (0.80 ± 0.35 µm) and electrosprayed PVP-copper salt composite microparticles (1.50 ± 0.70 µm). Energy-dispersive X-ray spectroscopy (EDS) evidenced the incorporation of copper into the produced composite materials. IR spectra confirmed the chemical composition and showed an interaction of Cu (II) ions with oxygen in the PVP resonant ring. Virucidal composite fibers inactivated 99.999% of coronavirus within 5 min of contact time, with moderate cytotoxicity to L929 cells, whereas the virucidal composite microparticles presented with a virucidal efficiency of 99.999% within 1440 min of exposure, with low cytotoxicity to L929 cells (mouse fibroblast). This produced virucidal composite materials have the potential to be applied in respirators, personal protective equipment, self-cleaning surfaces, and to fabric coat personal protective equipment against SARS-CoV-2, viral outbreaks, or pandemicsCOORDENAÇÃO DE APERFEIÇOAMENTO DE PESSOAL DE NÍVEL SUPERIOR - CAPESAbertoUNIVERSIDADE ESTADUAL DE CAMPINASSegundo, João de Deus Pereira de Moraes, 1988-Calais, Guilherme Bedeschi, 1993-Moura Júnior, Celso Fidelis de, 1992-Fonsêca, Jéssica Heline Lopes da, 1993-Tsukamoto, Junko, 1971-D'Avila, Marcos Akira, 1972-Arns, Clarice Weis, 1956-Beppu, Marisa Masumi, 1972-2022info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://hdl.handle.net/20.500.12733/6182SEGUNDO, João de Deus Pereira de Moraes et al. Virucidal PVP-copper salt composites against coronavirus produced by electrospinning and electrospraying. Polymers. Basel: MDPI, 2022. V. 14, n.9 (Oct., 2022) n. art. 14194157. Disponível em: https://hdl.handle.net/20.500.12733/6182. Acesso em: 24 mai. 2023.Inglêshttps://repositorio.unicamp.br/acervo/detalhe/1254069reponame:Repositório da Produção Científica e Intelectual da Unicampinstname:Universidade Estadual de Campinas (UNICAMP)instacron:UNICAMPinfo:eu-repo/semantics/openAccess2022-10-26T13:03:10Zoai:https://www.repositorio.unicamp.br/:1254069Repositório InstitucionalPUBhttp://repositorio.unicamp.br/oai/requestreposip@unicamp.bropendoar:2022-10-26T13:03:10Repositório da Produção Científica e Intelectual da Unicamp - Universidade Estadual de Campinas (UNICAMP)false |
| dc.title.none.fl_str_mv |
Virucidal PVP-copper salt composites against coronavirus produced by electrospinning and electrospraying |
| title |
Virucidal PVP-copper salt composites against coronavirus produced by electrospinning and electrospraying |
| spellingShingle |
Virucidal PVP-copper salt composites against coronavirus produced by electrospinning and electrospraying Segundo, João de Deus Pereira de Moraes, 1988- Eletrofiação Povidona Cobre Coronavírus Electrospinning Polyvinylpyrrolidone Copper Coronaviruses Artigo original |
| title_short |
Virucidal PVP-copper salt composites against coronavirus produced by electrospinning and electrospraying |
| title_full |
Virucidal PVP-copper salt composites against coronavirus produced by electrospinning and electrospraying |
| title_fullStr |
Virucidal PVP-copper salt composites against coronavirus produced by electrospinning and electrospraying |
| title_full_unstemmed |
Virucidal PVP-copper salt composites against coronavirus produced by electrospinning and electrospraying |
| title_sort |
Virucidal PVP-copper salt composites against coronavirus produced by electrospinning and electrospraying |
| author |
Segundo, João de Deus Pereira de Moraes, 1988- |
| author_facet |
Segundo, João de Deus Pereira de Moraes, 1988- Calais, Guilherme Bedeschi, 1993- Moura Júnior, Celso Fidelis de, 1992- Fonsêca, Jéssica Heline Lopes da, 1993- Tsukamoto, Junko, 1971- D'Avila, Marcos Akira, 1972- Arns, Clarice Weis, 1956- Beppu, Marisa Masumi, 1972- |
| author_role |
author |
| author2 |
Calais, Guilherme Bedeschi, 1993- Moura Júnior, Celso Fidelis de, 1992- Fonsêca, Jéssica Heline Lopes da, 1993- Tsukamoto, Junko, 1971- D'Avila, Marcos Akira, 1972- Arns, Clarice Weis, 1956- Beppu, Marisa Masumi, 1972- |
| author2_role |
author author author author author author author |
| dc.contributor.none.fl_str_mv |
UNIVERSIDADE ESTADUAL DE CAMPINAS |
| dc.contributor.author.fl_str_mv |
Segundo, João de Deus Pereira de Moraes, 1988- Calais, Guilherme Bedeschi, 1993- Moura Júnior, Celso Fidelis de, 1992- Fonsêca, Jéssica Heline Lopes da, 1993- Tsukamoto, Junko, 1971- D'Avila, Marcos Akira, 1972- Arns, Clarice Weis, 1956- Beppu, Marisa Masumi, 1972- |
| dc.subject.por.fl_str_mv |
Eletrofiação Povidona Cobre Coronavírus Electrospinning Polyvinylpyrrolidone Copper Coronaviruses Artigo original |
| topic |
Eletrofiação Povidona Cobre Coronavírus Electrospinning Polyvinylpyrrolidone Copper Coronaviruses Artigo original |
| description |
Agradecimentos: All authors would like to thank Coordination for the Improvement of Higher Education Personnel (CAPES) (proc. 88881.505221/2020-01) for the financial support |
| publishDate |
2022 |
| dc.date.none.fl_str_mv |
2022 |
| dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
| dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
| format |
article |
| status_str |
publishedVersion |
| dc.identifier.uri.fl_str_mv |
https://hdl.handle.net/20.500.12733/6182 SEGUNDO, João de Deus Pereira de Moraes et al. Virucidal PVP-copper salt composites against coronavirus produced by electrospinning and electrospraying. Polymers. Basel: MDPI, 2022. V. 14, n.9 (Oct., 2022) n. art. 14194157. Disponível em: https://hdl.handle.net/20.500.12733/6182. Acesso em: 24 mai. 2023. |
| url |
https://hdl.handle.net/20.500.12733/6182 |
| identifier_str_mv |
SEGUNDO, João de Deus Pereira de Moraes et al. Virucidal PVP-copper salt composites against coronavirus produced by electrospinning and electrospraying. Polymers. Basel: MDPI, 2022. V. 14, n.9 (Oct., 2022) n. art. 14194157. Disponível em: https://hdl.handle.net/20.500.12733/6182. Acesso em: 24 mai. 2023. |
| dc.language.iso.fl_str_mv |
Inglês |
| language_invalid_str_mv |
Inglês |
| dc.relation.none.fl_str_mv |
https://repositorio.unicamp.br/acervo/detalhe/1254069 |
| dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
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openAccess |
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application/pdf |
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reponame:Repositório da Produção Científica e Intelectual da Unicamp instname:Universidade Estadual de Campinas (UNICAMP) instacron:UNICAMP |
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Universidade Estadual de Campinas (UNICAMP) |
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UNICAMP |
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UNICAMP |
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Repositório da Produção Científica e Intelectual da Unicamp |
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Repositório da Produção Científica e Intelectual da Unicamp |
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Repositório da Produção Científica e Intelectual da Unicamp - Universidade Estadual de Campinas (UNICAMP) |
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reposip@unicamp.br |
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1766887330155593728 |