Development and characterization of fully hydrogenated soybean oil and high oleic sunflower oil beta-carotene loaded nanostructured lipid carriers

Detalhes bibliográficos
Autor(a) principal: Lüdtke, Fernanda Luisa, 1990-
Data de Publicação: 2023
Outros Autores: Grimaldi, Renato, 1962-, Cardoso, Lisandro Pavie, 1950-, Gigante, Mirna Lúcia, 1961-, Ribeiro, Ana Paula Badan, 1979-
Tipo de documento: Artigo
Título da fonte: Repositório da Produção Científica e Intelectual da Unicamp
Texto Completo: https://hdl.handle.net/20.500.12733/8796
Resumo: Agradecimentos: Fernanda Luisa Lüdtke thanks FAPESP (grants # 18/03172–0, # 19/05176–6, #16/11261–8 and 19/27354–3, São Paulo Research Foundation -FAPESP). Ana Paula Badan Ribeiro thanks the National Council for Scientific and Technological Development (Conselho Nacional de Desenvolvimento Científico e Tecnológico – CNPq) for the productivity grant (303429/2018–6). Lisandro Pavie Cardoso thanks the National Council for Scientific and Technological Development (Conselho Nacional de Desenvolvimento Científico e Tecnológico – CNPq) for financial support (grant #302626/2016–6). Currently, Lisandro Pavie Cardoso, is a retired professor at UNICAMP
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spelling Development and characterization of fully hydrogenated soybean oil and high oleic sunflower oil beta-carotene loaded nanostructured lipid carriersNanopartículas lípidicas solidasEmulsificantesEstabilidade físicaCompostos bioativosSolid lipid nanoparticlesEmulsifying agentsPhysical stabilityBioactive compoundsEntrapment efficiencyPolymorphic habitArtigo de pesquisaAgradecimentos: Fernanda Luisa Lüdtke thanks FAPESP (grants # 18/03172–0, # 19/05176–6, #16/11261–8 and 19/27354–3, São Paulo Research Foundation -FAPESP). Ana Paula Badan Ribeiro thanks the National Council for Scientific and Technological Development (Conselho Nacional de Desenvolvimento Científico e Tecnológico – CNPq) for the productivity grant (303429/2018–6). Lisandro Pavie Cardoso thanks the National Council for Scientific and Technological Development (Conselho Nacional de Desenvolvimento Científico e Tecnológico – CNPq) for financial support (grant #302626/2016–6). Currently, Lisandro Pavie Cardoso, is a retired professor at UNICAMPAbstract: Nanostructured lipid carriers (NLC) have shown great potential as a delivery system for lipophilic bioactive compounds as they provide protection, high water dispersibility, chemical stability, and oral bioavailability. The less compact crystal structure created by high- and low-melting-point lipids has more space for the entrapment of bioactive compounds, such as beta-carotene, the carotenoid with the highest provitamin A activity. The objective of this study was to produce and characterise beta-carotene-loaded NLC. The study assessed the physical and crystallization properties, entrapment efficiency (EE), and loading capacity (LC) of NLC produced with fully hydrogenated soybean oil and high oleic sunflower oil as high- and low-melting-point lipid matrices, respectively, and soy lecithin, Tween 80, and whey protein isolate (WPI) as emulsifiers. WPI promoted the production of NLC with larger particle size, lower physical stability, and lower IE and LC, compared with other emulsifiers. The melting range of the resulting NLC was within a suitable range for incorporation in foods, with a peak melting temperature above body temperatureFUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULO - FAPESPCONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICO - CNPQFechadoUNIVERSIDADE ESTADUAL DE CAMPINASLüdtke, Fernanda Luisa, 1990-Grimaldi, Renato, 1962-Cardoso, Lisandro Pavie, 1950-Gigante, Mirna Lúcia, 1961-Ribeiro, Ana Paula Badan, 1979-2023info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://hdl.handle.net/20.500.12733/8796LÜDTKE, Fernanda Luisa et al. Development and characterization of fully hydrogenated soybean oil and high oleic sunflower oil beta-carotene loaded nanostructured lipid carriers. Food biophysics. New York, NY : Springer, 2023. (Feb., 2023), p. 1-15. Disponível em: https://hdl.handle.net/20.500.12733/8796. Acesso em: 24 mai. 2023.Inglêshttps://repositorio.unicamp.br/acervo/detalhe/1267502reponame:Repositório da Produção Científica e Intelectual da Unicampinstname:Universidade Estadual de Campinas (UNICAMP)instacron:UNICAMPinfo:eu-repo/semantics/openAccess2023-04-26T12:52:38Zoai:https://www.repositorio.unicamp.br/:1267502Repositório InstitucionalPUBhttp://repositorio.unicamp.br/oai/requestreposip@unicamp.bropendoar:2023-04-26T12:52:38Repositório da Produção Científica e Intelectual da Unicamp - Universidade Estadual de Campinas (UNICAMP)false
dc.title.none.fl_str_mv Development and characterization of fully hydrogenated soybean oil and high oleic sunflower oil beta-carotene loaded nanostructured lipid carriers
title Development and characterization of fully hydrogenated soybean oil and high oleic sunflower oil beta-carotene loaded nanostructured lipid carriers
spellingShingle Development and characterization of fully hydrogenated soybean oil and high oleic sunflower oil beta-carotene loaded nanostructured lipid carriers
Lüdtke, Fernanda Luisa, 1990-
Nanopartículas lípidicas solidas
Emulsificantes
Estabilidade física
Compostos bioativos
Solid lipid nanoparticles
Emulsifying agents
Physical stability
Bioactive compounds
Entrapment efficiency
Polymorphic habit
Artigo de pesquisa
title_short Development and characterization of fully hydrogenated soybean oil and high oleic sunflower oil beta-carotene loaded nanostructured lipid carriers
title_full Development and characterization of fully hydrogenated soybean oil and high oleic sunflower oil beta-carotene loaded nanostructured lipid carriers
title_fullStr Development and characterization of fully hydrogenated soybean oil and high oleic sunflower oil beta-carotene loaded nanostructured lipid carriers
title_full_unstemmed Development and characterization of fully hydrogenated soybean oil and high oleic sunflower oil beta-carotene loaded nanostructured lipid carriers
title_sort Development and characterization of fully hydrogenated soybean oil and high oleic sunflower oil beta-carotene loaded nanostructured lipid carriers
author Lüdtke, Fernanda Luisa, 1990-
author_facet Lüdtke, Fernanda Luisa, 1990-
Grimaldi, Renato, 1962-
Cardoso, Lisandro Pavie, 1950-
Gigante, Mirna Lúcia, 1961-
Ribeiro, Ana Paula Badan, 1979-
author_role author
author2 Grimaldi, Renato, 1962-
Cardoso, Lisandro Pavie, 1950-
Gigante, Mirna Lúcia, 1961-
Ribeiro, Ana Paula Badan, 1979-
author2_role author
author
author
author
dc.contributor.none.fl_str_mv UNIVERSIDADE ESTADUAL DE CAMPINAS
dc.contributor.author.fl_str_mv Lüdtke, Fernanda Luisa, 1990-
Grimaldi, Renato, 1962-
Cardoso, Lisandro Pavie, 1950-
Gigante, Mirna Lúcia, 1961-
Ribeiro, Ana Paula Badan, 1979-
dc.subject.por.fl_str_mv Nanopartículas lípidicas solidas
Emulsificantes
Estabilidade física
Compostos bioativos
Solid lipid nanoparticles
Emulsifying agents
Physical stability
Bioactive compounds
Entrapment efficiency
Polymorphic habit
Artigo de pesquisa
topic Nanopartículas lípidicas solidas
Emulsificantes
Estabilidade física
Compostos bioativos
Solid lipid nanoparticles
Emulsifying agents
Physical stability
Bioactive compounds
Entrapment efficiency
Polymorphic habit
Artigo de pesquisa
description Agradecimentos: Fernanda Luisa Lüdtke thanks FAPESP (grants # 18/03172–0, # 19/05176–6, #16/11261–8 and 19/27354–3, São Paulo Research Foundation -FAPESP). Ana Paula Badan Ribeiro thanks the National Council for Scientific and Technological Development (Conselho Nacional de Desenvolvimento Científico e Tecnológico – CNPq) for the productivity grant (303429/2018–6). Lisandro Pavie Cardoso thanks the National Council for Scientific and Technological Development (Conselho Nacional de Desenvolvimento Científico e Tecnológico – CNPq) for financial support (grant #302626/2016–6). Currently, Lisandro Pavie Cardoso, is a retired professor at UNICAMP
publishDate 2023
dc.date.none.fl_str_mv 2023
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://hdl.handle.net/20.500.12733/8796
LÜDTKE, Fernanda Luisa et al. Development and characterization of fully hydrogenated soybean oil and high oleic sunflower oil beta-carotene loaded nanostructured lipid carriers. Food biophysics. New York, NY : Springer, 2023. (Feb., 2023), p. 1-15. Disponível em: https://hdl.handle.net/20.500.12733/8796. Acesso em: 24 mai. 2023.
url https://hdl.handle.net/20.500.12733/8796
identifier_str_mv LÜDTKE, Fernanda Luisa et al. Development and characterization of fully hydrogenated soybean oil and high oleic sunflower oil beta-carotene loaded nanostructured lipid carriers. Food biophysics. New York, NY : Springer, 2023. (Feb., 2023), p. 1-15. Disponível em: https://hdl.handle.net/20.500.12733/8796. Acesso em: 24 mai. 2023.
dc.language.iso.fl_str_mv Inglês
language_invalid_str_mv Inglês
dc.relation.none.fl_str_mv https://repositorio.unicamp.br/acervo/detalhe/1267502
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Repositório da Produção Científica e Intelectual da Unicamp
instname:Universidade Estadual de Campinas (UNICAMP)
instacron:UNICAMP
instname_str Universidade Estadual de Campinas (UNICAMP)
instacron_str UNICAMP
institution UNICAMP
reponame_str Repositório da Produção Científica e Intelectual da Unicamp
collection Repositório da Produção Científica e Intelectual da Unicamp
repository.name.fl_str_mv Repositório da Produção Científica e Intelectual da Unicamp - Universidade Estadual de Campinas (UNICAMP)
repository.mail.fl_str_mv reposip@unicamp.br
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