Flow cytometry diagnosis in myelodysplastic syndrome : current practice in Latin America and comparison with other regions of the world

Detalhes bibliográficos
Autor(a) principal: Lorand-Metze, Irene, 1945-
Data de Publicação: 2019
Tipo de documento: Artigo
Título da fonte: Repositório da Produção Científica e Intelectual da Unicamp
Texto Completo: https://hdl.handle.net/20.500.12733/1643718
Resumo: Agradecimentos: The authors thank the 265 participants who kindly respond to the survey. Without their cooperation this survey could not have been accomplished. Additionally, the authors thank to the Grupo Latinoamericano de Mielodisplasia (GLAM), Grupo Rioplatense de Citometria de Flujo (GRCF), Brazilian Group of Flow Cytometry (GBCFLUX), Sociedad Peruana de Hematologia (SPH), International Clinical Cytometry Society (ICCS), European Society for Clinical Cell Analysis (ESCCA), International Society for Advancement of Cytometry (ISAC), Purdue University Cytometry mailing list, Dutch Cytometry Society and Iberian Cytometry Society (SIC) for their support and contribution to survey distribution
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spelling Flow cytometry diagnosis in myelodysplastic syndrome : current practice in Latin America and comparison with other regions of the worldCitometria de fluxoSíndromes mielodisplásicasDiagnósticoMyelodysplastic syndromesFlow cytometryDiagnosisSurveyArtigo originalAgradecimentos: The authors thank the 265 participants who kindly respond to the survey. Without their cooperation this survey could not have been accomplished. Additionally, the authors thank to the Grupo Latinoamericano de Mielodisplasia (GLAM), Grupo Rioplatense de Citometria de Flujo (GRCF), Brazilian Group of Flow Cytometry (GBCFLUX), Sociedad Peruana de Hematologia (SPH), International Clinical Cytometry Society (ICCS), European Society for Clinical Cell Analysis (ESCCA), International Society for Advancement of Cytometry (ISAC), Purdue University Cytometry mailing list, Dutch Cytometry Society and Iberian Cytometry Society (SIC) for their support and contribution to survey distributionAbstract: Flow cytometry (FC) is a valuable tool for the diagnosis of myelodysplastic syndromes (MDS). We present results of a survey carried out to evaluate FC current practice for MDS diagnosis in Latin America (LA), focusing on markers used and characteristics of the clinical diagnostic report. Compliance to IMDSflow recommendations was also evaluated. These practices were then compared with those used in other countries. An online survey was sent through the Grupo Latino-Americano de Mielodisplasia to LA cytometrists and other international scientific societies. 91 responses from 15?LA countries were received. The median of the number of markers used was 20 ± 4.5, but only 8.1% of participants adopted the complete panel proposed by the International/European LeukemiaNet Working Group (IMDSflow). We received 140 eligible answers from regions other than LA (66 Europe, 59 USA-Canada, 8 Oceania, 6 Asia and 1 Africa). LA utilized more markers for MDS diagnosis than USA/Canada (p = 0.006), but similar to Europe. The use of MDS scoring systems differed among regions: 10.3% in LA, 0% USA/Canada and 25.7% Europe reported the "Ogata score". Finally, 52.0% of all participants included a general interpretation statement in the final report about the consistency of the FC results with MDS diagnosis, with no statistical differences between regions.This survey shows a low compliance with the IMDSflow recommendations and a scarce use of the scoring systems proposed in the literature. However, the number of surface markers used is high. We will work to develop a FC consensus for MDS diagnosis adapted to the clinical practice requirements in LAFechadoUNIVERSIDADE ESTADUAL DE CAMPINASLorand-Metze, Irene, 1945-2019info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://hdl.handle.net/20.500.12733/1643718LORAND-METZE, Irene. Flow cytometry diagnosis in myelodysplastic syndrome: current practice in Latin America and comparison with other regions of the world. Leukemia research. Oxford : Elsevier, 2019.. Vol. 79 (Apr., 2019), p. 69-74. Disponível em: https://hdl.handle.net/20.500.12733/1643718. Acesso em: 24 mai. 2023.Inglêshttps://repositorio.unicamp.br/acervo/detalhe/1173700reponame:Repositório da Produção Científica e Intelectual da Unicampinstname:Universidade Estadual de Campinas (UNICAMP)instacron:UNICAMPinfo:eu-repo/semantics/openAccess2022-03-30T16:33:28Zoai:https://www.repositorio.unicamp.br/:1173700Repositório InstitucionalPUBhttp://repositorio.unicamp.br/oai/requestreposip@unicamp.bropendoar:2022-03-30T16:33:28Repositório da Produção Científica e Intelectual da Unicamp - Universidade Estadual de Campinas (UNICAMP)false
dc.title.none.fl_str_mv Flow cytometry diagnosis in myelodysplastic syndrome : current practice in Latin America and comparison with other regions of the world
title Flow cytometry diagnosis in myelodysplastic syndrome : current practice in Latin America and comparison with other regions of the world
spellingShingle Flow cytometry diagnosis in myelodysplastic syndrome : current practice in Latin America and comparison with other regions of the world
Lorand-Metze, Irene, 1945-
Citometria de fluxo
Síndromes mielodisplásicas
Diagnóstico
Myelodysplastic syndromes
Flow cytometry
Diagnosis
Survey
Artigo original
title_short Flow cytometry diagnosis in myelodysplastic syndrome : current practice in Latin America and comparison with other regions of the world
title_full Flow cytometry diagnosis in myelodysplastic syndrome : current practice in Latin America and comparison with other regions of the world
title_fullStr Flow cytometry diagnosis in myelodysplastic syndrome : current practice in Latin America and comparison with other regions of the world
title_full_unstemmed Flow cytometry diagnosis in myelodysplastic syndrome : current practice in Latin America and comparison with other regions of the world
title_sort Flow cytometry diagnosis in myelodysplastic syndrome : current practice in Latin America and comparison with other regions of the world
author Lorand-Metze, Irene, 1945-
author_facet Lorand-Metze, Irene, 1945-
author_role author
dc.contributor.none.fl_str_mv UNIVERSIDADE ESTADUAL DE CAMPINAS
dc.contributor.author.fl_str_mv Lorand-Metze, Irene, 1945-
dc.subject.por.fl_str_mv Citometria de fluxo
Síndromes mielodisplásicas
Diagnóstico
Myelodysplastic syndromes
Flow cytometry
Diagnosis
Survey
Artigo original
topic Citometria de fluxo
Síndromes mielodisplásicas
Diagnóstico
Myelodysplastic syndromes
Flow cytometry
Diagnosis
Survey
Artigo original
description Agradecimentos: The authors thank the 265 participants who kindly respond to the survey. Without their cooperation this survey could not have been accomplished. Additionally, the authors thank to the Grupo Latinoamericano de Mielodisplasia (GLAM), Grupo Rioplatense de Citometria de Flujo (GRCF), Brazilian Group of Flow Cytometry (GBCFLUX), Sociedad Peruana de Hematologia (SPH), International Clinical Cytometry Society (ICCS), European Society for Clinical Cell Analysis (ESCCA), International Society for Advancement of Cytometry (ISAC), Purdue University Cytometry mailing list, Dutch Cytometry Society and Iberian Cytometry Society (SIC) for their support and contribution to survey distribution
publishDate 2019
dc.date.none.fl_str_mv 2019
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://hdl.handle.net/20.500.12733/1643718
LORAND-METZE, Irene. Flow cytometry diagnosis in myelodysplastic syndrome: current practice in Latin America and comparison with other regions of the world. Leukemia research. Oxford : Elsevier, 2019.. Vol. 79 (Apr., 2019), p. 69-74. Disponível em: https://hdl.handle.net/20.500.12733/1643718. Acesso em: 24 mai. 2023.
url https://hdl.handle.net/20.500.12733/1643718
identifier_str_mv LORAND-METZE, Irene. Flow cytometry diagnosis in myelodysplastic syndrome: current practice in Latin America and comparison with other regions of the world. Leukemia research. Oxford : Elsevier, 2019.. Vol. 79 (Apr., 2019), p. 69-74. Disponível em: https://hdl.handle.net/20.500.12733/1643718. Acesso em: 24 mai. 2023.
dc.language.iso.fl_str_mv Inglês
language_invalid_str_mv Inglês
dc.relation.none.fl_str_mv https://repositorio.unicamp.br/acervo/detalhe/1173700
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Repositório da Produção Científica e Intelectual da Unicamp
instname:Universidade Estadual de Campinas (UNICAMP)
instacron:UNICAMP
instname_str Universidade Estadual de Campinas (UNICAMP)
instacron_str UNICAMP
institution UNICAMP
reponame_str Repositório da Produção Científica e Intelectual da Unicamp
collection Repositório da Produção Científica e Intelectual da Unicamp
repository.name.fl_str_mv Repositório da Produção Científica e Intelectual da Unicamp - Universidade Estadual de Campinas (UNICAMP)
repository.mail.fl_str_mv reposip@unicamp.br
_version_ 1766887294738890752

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