Evaluation of a photoelectrochemical platform based on strontium titanate, sulfur doped carbon nitride and palladium nanoparticles for detection of SARS-CoV-2 spike glycoprotein S1

Detalhes bibliográficos
Autor(a) principal: Kubota, Lauro Tatsuo, 1964-
Data de Publicação: 2022
Tipo de documento: Artigo
Título da fonte: Repositório da Produção Científica e Intelectual da Unicamp
Texto Completo: https://hdl.handle.net/20.500.12733/6681
Resumo: Agradecimentos: The authors are grateful to Instituto Nacional de Ciência e Tecnologia em Bioanalítica (465389/2014-7); Fundação de Amparo à Pesquisa e ao Desenvolvimento Científico e Tecnológico do Maranhão - FAPEMA (INFRA-03186/18, INFRA-03195/18, UNIVERSAL-01057/19), and Conselho Nacional de Desenvolvimento Científico e Tecnológico - CNPq (308204/2018-2; 309828/2020-1). The authors gratefully acknowledge the Analytical Center of UFMA that provided the FTIR spectra. C. N. Botelho acknowledge to FAPEMA for the scholarship. The authors gratefully acknowledge to the Microscopy Center/UFMG that provided the morphological images and EDX spectrum
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spelling Evaluation of a photoelectrochemical platform based on strontium titanate, sulfur doped carbon nitride and palladium nanoparticles for detection of SARS-CoV-2 spike glycoprotein S1FotoeletroquimicaNanopartículas de paládioPhotoelectrochemistryPalladium nanoparticlesSARS CoV-2SrTiO3g-C3N4-SArtigo de pesquisaAgradecimentos: The authors are grateful to Instituto Nacional de Ciência e Tecnologia em Bioanalítica (465389/2014-7); Fundação de Amparo à Pesquisa e ao Desenvolvimento Científico e Tecnológico do Maranhão - FAPEMA (INFRA-03186/18, INFRA-03195/18, UNIVERSAL-01057/19), and Conselho Nacional de Desenvolvimento Científico e Tecnológico - CNPq (308204/2018-2; 309828/2020-1). The authors gratefully acknowledge the Analytical Center of UFMA that provided the FTIR spectra. C. N. Botelho acknowledge to FAPEMA for the scholarship. The authors gratefully acknowledge to the Microscopy Center/UFMG that provided the morphological images and EDX spectrumAbstract: This work aims to develop a photoelectrochemical (PEC) platform for detection of SARS-CoV-2 spike glyprotein S1. The PEC platform is based on the modification of a fluorine-doped tin oxide (FTO) coated glass slide with strontium titanate (SrTiO3 or ST), sulfur-doped carbon nitride (g–C3N4–S or CNS) and palladium nanoparticles entrapped in aluminum hydroxide matrix (PdAlO(OH) or PdNPs). The PEC platform was denoted as PdNPs/CNS/ST/FTO and it was characterized by SEM, TEM, FTIR, DRX, and EIS. The PEC response of the PdNPs/CNS/ST/FTO platform was optimized by evaluating the effects of the concentration of the donor molecule, the nature of the buffer, pH, antibody concentration, potential applied to the working electrode, and incubation time. The optimized PdNPs/CNS/ST/FTO PEC platform was modified with 5 µg mL-1 of antibody for determination of SARS-CoV-2 spike glycoprotein S1. A decrease in the photocurrent was observed with an increase in the concentration of SARS-CoV-2 from 1 fg mL-1 to 1000 pg mL-1 showing that the platform is a promising alternative for the detection of S1 protein from SARS-CoV-2. The designed PEC platform exhibited recovery percentages of 96.20% and 109.65% in artificial saliva samplesCONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICO - CNPQFUNDAÇÃO DE AMPARO À PESQUISA E AO DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICO DO MARANHÃO - FAPEMAFechadoUNIVERSIDADE ESTADUAL DE CAMPINASKubota, Lauro Tatsuo, 1964-2022info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://hdl.handle.net/20.500.12733/6681KUBOTA, Lauro Tatsuo. Evaluation of a photoelectrochemical platform based on strontium titanate, sulfur doped carbon nitride and palladium nanoparticles for detection of SARS-CoV-2 spike glycoprotein S1. Biosensors and bioelectronics: X. Amsterdam : Elsevier, 2022. Vol. 11 (Sept., 2022), n. art. 100167. Disponível em: https://hdl.handle.net/20.500.12733/6681. Acesso em: 24 mai. 2023.Inglêshttps://repositorio.unicamp.br/acervo/detalhe/1254513reponame:Repositório da Produção Científica e Intelectual da Unicampinstname:Universidade Estadual de Campinas (UNICAMP)instacron:UNICAMPinfo:eu-repo/semantics/openAccess2022-12-01T16:40:03Zoai:https://www.repositorio.unicamp.br/:1254513Repositório InstitucionalPUBhttp://repositorio.unicamp.br/oai/requestreposip@unicamp.bropendoar:2022-12-01T16:40:03Repositório da Produção Científica e Intelectual da Unicamp - Universidade Estadual de Campinas (UNICAMP)false
dc.title.none.fl_str_mv Evaluation of a photoelectrochemical platform based on strontium titanate, sulfur doped carbon nitride and palladium nanoparticles for detection of SARS-CoV-2 spike glycoprotein S1
title Evaluation of a photoelectrochemical platform based on strontium titanate, sulfur doped carbon nitride and palladium nanoparticles for detection of SARS-CoV-2 spike glycoprotein S1
spellingShingle Evaluation of a photoelectrochemical platform based on strontium titanate, sulfur doped carbon nitride and palladium nanoparticles for detection of SARS-CoV-2 spike glycoprotein S1
Kubota, Lauro Tatsuo, 1964-
Fotoeletroquimica
Nanopartículas de paládio
Photoelectrochemistry
Palladium nanoparticles
SARS CoV-2
SrTiO3
g-C3N4-S
Artigo de pesquisa
title_short Evaluation of a photoelectrochemical platform based on strontium titanate, sulfur doped carbon nitride and palladium nanoparticles for detection of SARS-CoV-2 spike glycoprotein S1
title_full Evaluation of a photoelectrochemical platform based on strontium titanate, sulfur doped carbon nitride and palladium nanoparticles for detection of SARS-CoV-2 spike glycoprotein S1
title_fullStr Evaluation of a photoelectrochemical platform based on strontium titanate, sulfur doped carbon nitride and palladium nanoparticles for detection of SARS-CoV-2 spike glycoprotein S1
title_full_unstemmed Evaluation of a photoelectrochemical platform based on strontium titanate, sulfur doped carbon nitride and palladium nanoparticles for detection of SARS-CoV-2 spike glycoprotein S1
title_sort Evaluation of a photoelectrochemical platform based on strontium titanate, sulfur doped carbon nitride and palladium nanoparticles for detection of SARS-CoV-2 spike glycoprotein S1
author Kubota, Lauro Tatsuo, 1964-
author_facet Kubota, Lauro Tatsuo, 1964-
author_role author
dc.contributor.none.fl_str_mv UNIVERSIDADE ESTADUAL DE CAMPINAS
dc.contributor.author.fl_str_mv Kubota, Lauro Tatsuo, 1964-
dc.subject.por.fl_str_mv Fotoeletroquimica
Nanopartículas de paládio
Photoelectrochemistry
Palladium nanoparticles
SARS CoV-2
SrTiO3
g-C3N4-S
Artigo de pesquisa
topic Fotoeletroquimica
Nanopartículas de paládio
Photoelectrochemistry
Palladium nanoparticles
SARS CoV-2
SrTiO3
g-C3N4-S
Artigo de pesquisa
description Agradecimentos: The authors are grateful to Instituto Nacional de Ciência e Tecnologia em Bioanalítica (465389/2014-7); Fundação de Amparo à Pesquisa e ao Desenvolvimento Científico e Tecnológico do Maranhão - FAPEMA (INFRA-03186/18, INFRA-03195/18, UNIVERSAL-01057/19), and Conselho Nacional de Desenvolvimento Científico e Tecnológico - CNPq (308204/2018-2; 309828/2020-1). The authors gratefully acknowledge the Analytical Center of UFMA that provided the FTIR spectra. C. N. Botelho acknowledge to FAPEMA for the scholarship. The authors gratefully acknowledge to the Microscopy Center/UFMG that provided the morphological images and EDX spectrum
publishDate 2022
dc.date.none.fl_str_mv 2022
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://hdl.handle.net/20.500.12733/6681
KUBOTA, Lauro Tatsuo. Evaluation of a photoelectrochemical platform based on strontium titanate, sulfur doped carbon nitride and palladium nanoparticles for detection of SARS-CoV-2 spike glycoprotein S1. Biosensors and bioelectronics: X. Amsterdam : Elsevier, 2022. Vol. 11 (Sept., 2022), n. art. 100167. Disponível em: https://hdl.handle.net/20.500.12733/6681. Acesso em: 24 mai. 2023.
url https://hdl.handle.net/20.500.12733/6681
identifier_str_mv KUBOTA, Lauro Tatsuo. Evaluation of a photoelectrochemical platform based on strontium titanate, sulfur doped carbon nitride and palladium nanoparticles for detection of SARS-CoV-2 spike glycoprotein S1. Biosensors and bioelectronics: X. Amsterdam : Elsevier, 2022. Vol. 11 (Sept., 2022), n. art. 100167. Disponível em: https://hdl.handle.net/20.500.12733/6681. Acesso em: 24 mai. 2023.
dc.language.iso.fl_str_mv Inglês
language_invalid_str_mv Inglês
dc.relation.none.fl_str_mv https://repositorio.unicamp.br/acervo/detalhe/1254513
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Repositório da Produção Científica e Intelectual da Unicamp
instname:Universidade Estadual de Campinas (UNICAMP)
instacron:UNICAMP
instname_str Universidade Estadual de Campinas (UNICAMP)
instacron_str UNICAMP
institution UNICAMP
reponame_str Repositório da Produção Científica e Intelectual da Unicamp
collection Repositório da Produção Científica e Intelectual da Unicamp
repository.name.fl_str_mv Repositório da Produção Científica e Intelectual da Unicamp - Universidade Estadual de Campinas (UNICAMP)
repository.mail.fl_str_mv reposip@unicamp.br
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