Combined effect of dynapenia (muscle weakness) and low vitamin D status on incident disability

Detalhes bibliográficos
Autor(a) principal: Borim, Flávia Silva Arbex, 1977-
Data de Publicação: 2019
Outros Autores: Neri, Anita Liberalesso, 1946-, Silva, Marcela Fernandes, 1991-
Tipo de documento: Artigo
Título da fonte: Repositório da Produção Científica e Intelectual da Unicamp
Texto Completo: https://hdl.handle.net/20.500.12733/1643599
Resumo: Agradecimentos: We thank all of the staff working on the English Longitudinal Study of Ageing (ELSA) and the participants in the project
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spelling Combined effect of dynapenia (muscle weakness) and low vitamin D status on incident disabilityVitamina DForça muscularVitamin DMuscle strengthHandgrip25(OH) DArtigo originalAgradecimentos: We thank all of the staff working on the English Longitudinal Study of Ageing (ELSA) and the participants in the projectAbstract: There is little epidemiologic evidence considering the combined effect of dynapenia and low 25-hydroxyvitamin D [25 (OH) D] on incident disability. Our aim was to investigate whether the combination of dynapenia and low 25 (OH) D serum levels increases the risk of activities of daily living (ADL) incident disability. The baseline sample was categorized into 4 groups (ie, nondynapenic/normal 25 (OH) D, low 25 (OH) D only, dynapenic only, and dynapenic/low 25 (OH) D according to their handgrip strength (<26 kg for men and <16 kg for women) and 25 (OH) D (=50 nmol/L). The outcome was the presence of any ADL disability 2 years after baseline according to the modified Katz Index. Incidence rate ratios (IRRs) adjusted by sociodemographic, behavioral, and clinical characteristics were estimated using Poisson regression. The fully adjusted model showed that older adults with dynapenia only and those with lower serum levels of 25 (OH) D combined with dynapenia had higher incident ADL disability risk compared with nondynapenic and those with normal serum levels of 25 (OH) D. The IRRs for lower 25 (OH) D serum levels combined with dynapenia were higher than for dynapenia only, however, the confidence intervals (CIs) showed similar effect for these 2 groups. The IRRs were 1.31 for low 25(OH) D only (95% CI 0.99–1.74), 1.77 for dynapenia only (95% CI 1.08–2.88), and 1.94 for combined dynapenia and low 25(OH)D (95% CI 1.28–2.94). Dynapenia only and dynapenia combined with low 25 (OH) D serum levels were important risk factors for ADL disability in middle-aged individuals and older adults in 2 years of follow-upFechadoUNIVERSIDADE ESTADUAL DE CAMPINASBorim, Flávia Silva Arbex, 1977-Neri, Anita Liberalesso, 1946-Silva, Marcela Fernandes, 1991-2019info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://hdl.handle.net/20.500.12733/1643599BORIM, Flávia Silva Arbex; NERI, Anita Liberalesso; SILVA, Marcela Fernandes. Combined effect of dynapenia (muscle weakness) and low vitamin D status on incident disability. Journal american medical directors association. Philadelphia, PA : Elsevier, 2019.. Vol. 20, n. 1 (Jan., 2019), p. 47-52. Disponível em: https://hdl.handle.net/20.500.12733/1643599. Acesso em: 24 mai. 2023.Inglêshttps://repositorio.unicamp.br/acervo/detalhe/1173462reponame:Repositório da Produção Científica e Intelectual da Unicampinstname:Universidade Estadual de Campinas (UNICAMP)instacron:UNICAMPinfo:eu-repo/semantics/openAccess2022-02-18T11:22:38Zoai:https://www.repositorio.unicamp.br/:1173462Repositório InstitucionalPUBhttp://repositorio.unicamp.br/oai/requestreposip@unicamp.bropendoar:2022-02-18T11:22:38Repositório da Produção Científica e Intelectual da Unicamp - Universidade Estadual de Campinas (UNICAMP)false
dc.title.none.fl_str_mv Combined effect of dynapenia (muscle weakness) and low vitamin D status on incident disability
title Combined effect of dynapenia (muscle weakness) and low vitamin D status on incident disability
spellingShingle Combined effect of dynapenia (muscle weakness) and low vitamin D status on incident disability
Borim, Flávia Silva Arbex, 1977-
Vitamina D
Força muscular
Vitamin D
Muscle strength
Handgrip
25(OH) D
Artigo original
title_short Combined effect of dynapenia (muscle weakness) and low vitamin D status on incident disability
title_full Combined effect of dynapenia (muscle weakness) and low vitamin D status on incident disability
title_fullStr Combined effect of dynapenia (muscle weakness) and low vitamin D status on incident disability
title_full_unstemmed Combined effect of dynapenia (muscle weakness) and low vitamin D status on incident disability
title_sort Combined effect of dynapenia (muscle weakness) and low vitamin D status on incident disability
author Borim, Flávia Silva Arbex, 1977-
author_facet Borim, Flávia Silva Arbex, 1977-
Neri, Anita Liberalesso, 1946-
Silva, Marcela Fernandes, 1991-
author_role author
author2 Neri, Anita Liberalesso, 1946-
Silva, Marcela Fernandes, 1991-
author2_role author
author
dc.contributor.none.fl_str_mv UNIVERSIDADE ESTADUAL DE CAMPINAS
dc.contributor.author.fl_str_mv Borim, Flávia Silva Arbex, 1977-
Neri, Anita Liberalesso, 1946-
Silva, Marcela Fernandes, 1991-
dc.subject.por.fl_str_mv Vitamina D
Força muscular
Vitamin D
Muscle strength
Handgrip
25(OH) D
Artigo original
topic Vitamina D
Força muscular
Vitamin D
Muscle strength
Handgrip
25(OH) D
Artigo original
description Agradecimentos: We thank all of the staff working on the English Longitudinal Study of Ageing (ELSA) and the participants in the project
publishDate 2019
dc.date.none.fl_str_mv 2019
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://hdl.handle.net/20.500.12733/1643599
BORIM, Flávia Silva Arbex; NERI, Anita Liberalesso; SILVA, Marcela Fernandes. Combined effect of dynapenia (muscle weakness) and low vitamin D status on incident disability. Journal american medical directors association. Philadelphia, PA : Elsevier, 2019.. Vol. 20, n. 1 (Jan., 2019), p. 47-52. Disponível em: https://hdl.handle.net/20.500.12733/1643599. Acesso em: 24 mai. 2023.
url https://hdl.handle.net/20.500.12733/1643599
identifier_str_mv BORIM, Flávia Silva Arbex; NERI, Anita Liberalesso; SILVA, Marcela Fernandes. Combined effect of dynapenia (muscle weakness) and low vitamin D status on incident disability. Journal american medical directors association. Philadelphia, PA : Elsevier, 2019.. Vol. 20, n. 1 (Jan., 2019), p. 47-52. Disponível em: https://hdl.handle.net/20.500.12733/1643599. Acesso em: 24 mai. 2023.
dc.language.iso.fl_str_mv Inglês
language_invalid_str_mv Inglês
dc.relation.none.fl_str_mv https://repositorio.unicamp.br/acervo/detalhe/1173462
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Repositório da Produção Científica e Intelectual da Unicamp
instname:Universidade Estadual de Campinas (UNICAMP)
instacron:UNICAMP
instname_str Universidade Estadual de Campinas (UNICAMP)
instacron_str UNICAMP
institution UNICAMP
reponame_str Repositório da Produção Científica e Intelectual da Unicamp
collection Repositório da Produção Científica e Intelectual da Unicamp
repository.name.fl_str_mv Repositório da Produção Científica e Intelectual da Unicamp - Universidade Estadual de Campinas (UNICAMP)
repository.mail.fl_str_mv reposip@unicamp.br
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