New approaches toward anti-Rhipicephalus (Boophilus) microplus tick vaccine

Detalhes bibliográficos
Autor(a) principal: Parizi,Luís Fernando
Data de Publicação: 2009
Outros Autores: Pohl,Paula Cristiane, Masuda,Aoi, Vaz Junior,Itabajara da Silva
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista Brasileira de Parasitologia Veterinária (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1984-29612009000100001
Resumo: The tick Rhipicephalus (Boophilus) microplus (formerly Boophilus microplus) is the major ectoparasite affecting livestock in America, Asia, Africa, and Oceania. Conventional tick control is based on the use of acaricides but immunization of bovines with tick gut proteins induces only a partial protective immune response. Based on this information, distinct research groups have explored the possibility of protecting the animals by inducing an immune response against other tick proteins. However, the antigens so far described do not induce the necessary protection for suppressing the use of acaricides. Currently, several groups are engaged in identifying new tick proteins to be used as targets for the development of new vaccines. This approach focuses on the enhancement of the immunogenicity of antigens already tested by incorporating new adjuvants or formulations and by searching for new antigens. This paper reviews the work done by Brazilian researchers to develop a vaccine against this tick.
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spelling New approaches toward anti-Rhipicephalus (Boophilus) microplus tick vaccineBoophilus microplusRhipicephalus microplusvaccinetickcontrolThe tick Rhipicephalus (Boophilus) microplus (formerly Boophilus microplus) is the major ectoparasite affecting livestock in America, Asia, Africa, and Oceania. Conventional tick control is based on the use of acaricides but immunization of bovines with tick gut proteins induces only a partial protective immune response. Based on this information, distinct research groups have explored the possibility of protecting the animals by inducing an immune response against other tick proteins. However, the antigens so far described do not induce the necessary protection for suppressing the use of acaricides. Currently, several groups are engaged in identifying new tick proteins to be used as targets for the development of new vaccines. This approach focuses on the enhancement of the immunogenicity of antigens already tested by incorporating new adjuvants or formulations and by searching for new antigens. This paper reviews the work done by Brazilian researchers to develop a vaccine against this tick.Colégio Brasileiro de Parasitologia Veterinária2009-03-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1984-29612009000100001Revista Brasileira de Parasitologia Veterinária v.18 n.1 2009reponame:Revista Brasileira de Parasitologia Veterinária (Online)instname:Colégio Brasileiro de Parasitologia Veterinária (CBPV)instacron:CBPV10.4322/rbpv.01801001info:eu-repo/semantics/openAccessParizi,Luís FernandoPohl,Paula CristianeMasuda,AoiVaz Junior,Itabajara da Silvaeng2012-04-12T00:00:00Zoai:scielo:S1984-29612009000100001Revistahttp://www.scielo.br/scielo.php?script=sci_serial&lng=pt&pid=1984-2961https://old.scielo.br/oai/scielo-oai.php||zacariascbpv@fcav.unesp.br1984-29610103-846Xopendoar:2012-04-12T00:00Revista Brasileira de Parasitologia Veterinária (Online) - Colégio Brasileiro de Parasitologia Veterinária (CBPV)false
dc.title.none.fl_str_mv New approaches toward anti-Rhipicephalus (Boophilus) microplus tick vaccine
title New approaches toward anti-Rhipicephalus (Boophilus) microplus tick vaccine
spellingShingle New approaches toward anti-Rhipicephalus (Boophilus) microplus tick vaccine
Parizi,Luís Fernando
Boophilus microplus
Rhipicephalus microplus
vaccine
tick
control
title_short New approaches toward anti-Rhipicephalus (Boophilus) microplus tick vaccine
title_full New approaches toward anti-Rhipicephalus (Boophilus) microplus tick vaccine
title_fullStr New approaches toward anti-Rhipicephalus (Boophilus) microplus tick vaccine
title_full_unstemmed New approaches toward anti-Rhipicephalus (Boophilus) microplus tick vaccine
title_sort New approaches toward anti-Rhipicephalus (Boophilus) microplus tick vaccine
author Parizi,Luís Fernando
author_facet Parizi,Luís Fernando
Pohl,Paula Cristiane
Masuda,Aoi
Vaz Junior,Itabajara da Silva
author_role author
author2 Pohl,Paula Cristiane
Masuda,Aoi
Vaz Junior,Itabajara da Silva
author2_role author
author
author
dc.contributor.author.fl_str_mv Parizi,Luís Fernando
Pohl,Paula Cristiane
Masuda,Aoi
Vaz Junior,Itabajara da Silva
dc.subject.por.fl_str_mv Boophilus microplus
Rhipicephalus microplus
vaccine
tick
control
topic Boophilus microplus
Rhipicephalus microplus
vaccine
tick
control
description The tick Rhipicephalus (Boophilus) microplus (formerly Boophilus microplus) is the major ectoparasite affecting livestock in America, Asia, Africa, and Oceania. Conventional tick control is based on the use of acaricides but immunization of bovines with tick gut proteins induces only a partial protective immune response. Based on this information, distinct research groups have explored the possibility of protecting the animals by inducing an immune response against other tick proteins. However, the antigens so far described do not induce the necessary protection for suppressing the use of acaricides. Currently, several groups are engaged in identifying new tick proteins to be used as targets for the development of new vaccines. This approach focuses on the enhancement of the immunogenicity of antigens already tested by incorporating new adjuvants or formulations and by searching for new antigens. This paper reviews the work done by Brazilian researchers to develop a vaccine against this tick.
publishDate 2009
dc.date.none.fl_str_mv 2009-03-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1984-29612009000100001
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1984-29612009000100001
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.4322/rbpv.01801001
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Colégio Brasileiro de Parasitologia Veterinária
publisher.none.fl_str_mv Colégio Brasileiro de Parasitologia Veterinária
dc.source.none.fl_str_mv Revista Brasileira de Parasitologia Veterinária v.18 n.1 2009
reponame:Revista Brasileira de Parasitologia Veterinária (Online)
instname:Colégio Brasileiro de Parasitologia Veterinária (CBPV)
instacron:CBPV
instname_str Colégio Brasileiro de Parasitologia Veterinária (CBPV)
instacron_str CBPV
institution CBPV
reponame_str Revista Brasileira de Parasitologia Veterinária (Online)
collection Revista Brasileira de Parasitologia Veterinária (Online)
repository.name.fl_str_mv Revista Brasileira de Parasitologia Veterinária (Online) - Colégio Brasileiro de Parasitologia Veterinária (CBPV)
repository.mail.fl_str_mv ||zacariascbpv@fcav.unesp.br
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