Non Invasive Electrotherapy in the Process of Bone Repair in Different Periods After Fracture: Experimental Study in Wistar Rats

Detalhes bibliográficos
Autor(a) principal: Bertolini, Sônia Maria Marques Gomes
Data de Publicação: 2008
Outros Autores: Cararo, Deisy Carla, Oliveira, Priscila Daniele de, Martins, Priscilla da Costa
Tipo de documento: Artigo
Idioma: por
Título da fonte: Saúde e Pesquisa (Online)
Texto Completo: https://periodicos.unicesumar.edu.br/index.php/saudpesq/article/view/703
Resumo: This research had as objective evaluate the effectiveness of the application of a non-invasive electric current in rats´ tibia osteogenesis, at different periods after broken. Were used 30 Rattus navergicus albinus, Wistar variety, males, distributed, initially, into 2 groups of 15 animals and each group was subdivided into 3 subgroups with 5 animals. A broken on the level of diafisis on the left tibia of every animal was induced on them. The animals of the experimental group, after 3 days, were submitted to the electric-stimulation (galvanic current). The application of the electric current took 20 minutes, extending for 2, 4 and 6 weeks. All the animals were radiographed after the bone injury and at the end of the experiment. At the final of the treatment, the animals were sacrificed and then, the histological treatment had start. The results of the histological and radiological analysis showed that all the animals of the experimental group, no matter the after-breaking period, had showed acceleration in the process of bone consolidation. After 4 weeks since broken, the animals submitted to the electro-stimulation had no signals of injury. Through the histological analysis, at the second week after broken, in the electro-stimulated animals, was possible to identify the spongy bone with bone trabecullas well developed. In the non-treated group, this trabecullas, although found occupying partially the bone fissure, showed an ample intertrabecullar space, filled with fibrocartilaginous tissue. The final results of this research reinforce what is found in the literature, indicating that the use of a non-invasive electric current is efficient on the enhance of the speed on the bone reconstitution.
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spelling Non Invasive Electrotherapy in the Process of Bone Repair in Different Periods After Fracture: Experimental Study in Wistar RatsEletroterapia Não-Invasiva no Processo de Reparação Óssea em Diferentes Períodos Pós-Fratura: Estudo Experimental em Ratos da Linhagem WistarEletroestimulaçãoFraturaOsteogêneseElectro-stimulationFractureOsteogenesis.This research had as objective evaluate the effectiveness of the application of a non-invasive electric current in rats´ tibia osteogenesis, at different periods after broken. Were used 30 Rattus navergicus albinus, Wistar variety, males, distributed, initially, into 2 groups of 15 animals and each group was subdivided into 3 subgroups with 5 animals. A broken on the level of diafisis on the left tibia of every animal was induced on them. The animals of the experimental group, after 3 days, were submitted to the electric-stimulation (galvanic current). The application of the electric current took 20 minutes, extending for 2, 4 and 6 weeks. All the animals were radiographed after the bone injury and at the end of the experiment. At the final of the treatment, the animals were sacrificed and then, the histological treatment had start. The results of the histological and radiological analysis showed that all the animals of the experimental group, no matter the after-breaking period, had showed acceleration in the process of bone consolidation. After 4 weeks since broken, the animals submitted to the electro-stimulation had no signals of injury. Through the histological analysis, at the second week after broken, in the electro-stimulated animals, was possible to identify the spongy bone with bone trabecullas well developed. In the non-treated group, this trabecullas, although found occupying partially the bone fissure, showed an ample intertrabecullar space, filled with fibrocartilaginous tissue. The final results of this research reinforce what is found in the literature, indicating that the use of a non-invasive electric current is efficient on the enhance of the speed on the bone reconstitution.Este trabalho teve como objetivo avaliar a eficácia da aplicação da corrente elétrica não-invasiva na osteogênese da tíbia de ratos em diferentes períodos pós-fratura. Foram utilizados 30 Rattus navergicus albinus, variedade Wistar, machos, inicialmente distribuídos em dois grupos de 15 animais e cada grupo foi subdividido em três subgrupos contendo cinco animais. Foi induzida uma fratura em nível da diáfise da tíbia esquerda de todos animais. Os animais do grupo-experimental, após três dias, foram submetidos à eletroestimulação (corrente galvânica). A aplicação da corrente elétrica teve duração de 20 min, estendendo-se por duas, quatro e seis semanas. Os animais foram radiografados após a lesão óssea e no final do experimento. Ao término do experimento, os animais foram sacrificados e procedeu-se ao tratamento histológico. Os resultados da análise histológica mostraram que todos animais do grupo-experimental, sacrificados na 2ª e 4ª semanas (fase colágena e osteogênica, respectivamente), apresentavam um estágio mais avançado no processo de reparo ósseo, quando comparados aos animais do grupo-controle. Já nos animais sacrificados na 6ª semana em relação ao grupo-tratado, o local da lesão não revelou diferença estrutural no osso neoformado (fase de remodelação óssea). É possível concluir que a corrente elétrica direta não-invasiva influencia na neoformação óssea, desde a fase fibroblástica, passando pela fase de colágeno até a fase osteogênica, acelerando o preenchimento ósseo em ratos submetidos à lesão de tíbia.Universidade Cesumar - UniCesumar2008-06-27info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionAvaliado por Paresapplication/pdfhttps://periodicos.unicesumar.edu.br/index.php/saudpesq/article/view/703Saúde e Pesquisa; Vol 1 No 1 (2008): jan./abr.; 25-29Saúde e Pesquisa; v. 1 n. 1 (2008): jan./abr.; 25-292176-9206reponame:Saúde e Pesquisa (Online)instname:Cesumar Diretoria de Pesquisainstacron:CESUMARporhttps://periodicos.unicesumar.edu.br/index.php/saudpesq/article/view/703/575Bertolini, Sônia Maria Marques GomesCararo, Deisy CarlaOliveira, Priscila Daniele deMartins, Priscilla da Costainfo:eu-repo/semantics/openAccess2022-05-23T19:04:31Zoai:ojs.pkp.sfu.ca:article/703Revistahttps://periodicos.unicesumar.edu.br/index.php/saudpesqPUBhttps://periodicos.unicesumar.edu.br/index.php/saudpesq/oainaep@cesumar.br2176-92061983-1870opendoar:2022-05-23T19:04:31Saúde e Pesquisa (Online) - Cesumar Diretoria de Pesquisafalse
dc.title.none.fl_str_mv Non Invasive Electrotherapy in the Process of Bone Repair in Different Periods After Fracture: Experimental Study in Wistar Rats
Eletroterapia Não-Invasiva no Processo de Reparação Óssea em Diferentes Períodos Pós-Fratura: Estudo Experimental em Ratos da Linhagem Wistar
title Non Invasive Electrotherapy in the Process of Bone Repair in Different Periods After Fracture: Experimental Study in Wistar Rats
spellingShingle Non Invasive Electrotherapy in the Process of Bone Repair in Different Periods After Fracture: Experimental Study in Wistar Rats
Bertolini, Sônia Maria Marques Gomes
Eletroestimulação
Fratura
Osteogênese
Electro-stimulation
Fracture
Osteogenesis.
title_short Non Invasive Electrotherapy in the Process of Bone Repair in Different Periods After Fracture: Experimental Study in Wistar Rats
title_full Non Invasive Electrotherapy in the Process of Bone Repair in Different Periods After Fracture: Experimental Study in Wistar Rats
title_fullStr Non Invasive Electrotherapy in the Process of Bone Repair in Different Periods After Fracture: Experimental Study in Wistar Rats
title_full_unstemmed Non Invasive Electrotherapy in the Process of Bone Repair in Different Periods After Fracture: Experimental Study in Wistar Rats
title_sort Non Invasive Electrotherapy in the Process of Bone Repair in Different Periods After Fracture: Experimental Study in Wistar Rats
author Bertolini, Sônia Maria Marques Gomes
author_facet Bertolini, Sônia Maria Marques Gomes
Cararo, Deisy Carla
Oliveira, Priscila Daniele de
Martins, Priscilla da Costa
author_role author
author2 Cararo, Deisy Carla
Oliveira, Priscila Daniele de
Martins, Priscilla da Costa
author2_role author
author
author
dc.contributor.author.fl_str_mv Bertolini, Sônia Maria Marques Gomes
Cararo, Deisy Carla
Oliveira, Priscila Daniele de
Martins, Priscilla da Costa
dc.subject.por.fl_str_mv Eletroestimulação
Fratura
Osteogênese
Electro-stimulation
Fracture
Osteogenesis.
topic Eletroestimulação
Fratura
Osteogênese
Electro-stimulation
Fracture
Osteogenesis.
description This research had as objective evaluate the effectiveness of the application of a non-invasive electric current in rats´ tibia osteogenesis, at different periods after broken. Were used 30 Rattus navergicus albinus, Wistar variety, males, distributed, initially, into 2 groups of 15 animals and each group was subdivided into 3 subgroups with 5 animals. A broken on the level of diafisis on the left tibia of every animal was induced on them. The animals of the experimental group, after 3 days, were submitted to the electric-stimulation (galvanic current). The application of the electric current took 20 minutes, extending for 2, 4 and 6 weeks. All the animals were radiographed after the bone injury and at the end of the experiment. At the final of the treatment, the animals were sacrificed and then, the histological treatment had start. The results of the histological and radiological analysis showed that all the animals of the experimental group, no matter the after-breaking period, had showed acceleration in the process of bone consolidation. After 4 weeks since broken, the animals submitted to the electro-stimulation had no signals of injury. Through the histological analysis, at the second week after broken, in the electro-stimulated animals, was possible to identify the spongy bone with bone trabecullas well developed. In the non-treated group, this trabecullas, although found occupying partially the bone fissure, showed an ample intertrabecullar space, filled with fibrocartilaginous tissue. The final results of this research reinforce what is found in the literature, indicating that the use of a non-invasive electric current is efficient on the enhance of the speed on the bone reconstitution.
publishDate 2008
dc.date.none.fl_str_mv 2008-06-27
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Avaliado por Pares
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://periodicos.unicesumar.edu.br/index.php/saudpesq/article/view/703
url https://periodicos.unicesumar.edu.br/index.php/saudpesq/article/view/703
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://periodicos.unicesumar.edu.br/index.php/saudpesq/article/view/703/575
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade Cesumar - UniCesumar
publisher.none.fl_str_mv Universidade Cesumar - UniCesumar
dc.source.none.fl_str_mv Saúde e Pesquisa; Vol 1 No 1 (2008): jan./abr.; 25-29
Saúde e Pesquisa; v. 1 n. 1 (2008): jan./abr.; 25-29
2176-9206
reponame:Saúde e Pesquisa (Online)
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reponame_str Saúde e Pesquisa (Online)
collection Saúde e Pesquisa (Online)
repository.name.fl_str_mv Saúde e Pesquisa (Online) - Cesumar Diretoria de Pesquisa
repository.mail.fl_str_mv naep@cesumar.br
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