Efficacy of the adjuvanted subunit protein COVID-19 vaccine, SCB-2019: a phase 2 and 3 multicentre, double-blind, randomised, placebo-controlled trial

Detalhes bibliográficos
Autor(a) principal: Bravo, Lulu
Data de Publicação: 2022
Outros Autores: Smolenov, Igor, Han, Htay Htay, Li, Ping, Hosain, Romana, Rockhold, Frank, Clemens, Sue Ann Costa, Roa Jr, Camilo, Borja-Tabora, Charissa, Quinsaat, Antoinette, Lopez, Pio, López-Medina, Eduardo, Brochado, Leonardo, Hernández, Eder A., Reynales, Humberto, Medina, Tatiana, Velasquez, Hector, Toloza, Leonardo Bautista, Rodriguez, Edith Johana, Salazar, Dora Ines Molina de, Rodríguez, Camilo A., Sprinz, Eduardo, Cerbino-Neto, José, Luz, Kleber Giovanni, Schwarzbold, Alexandre Vargas, Paiva, Maria Sanali, Carlos, Josefina, Montellano, May Emmeline B., Los Reyes, Mari Rose A. de, Yu, Charles Y., Alberto, Edison R., Panaligan, Mario M., Salvani-Bautista, Milagros, Buntinx, Erik, Hites, Maya, Martinot, Jean-Benoit, Bhorat, Qasim E., Badat, Aysha, Baccarini, Carmen, Hu, Branda, Jurgens, Jaco, Engelbrecht, Jan, Ambrosino, Donna, Richmond, Peter, Siber, George, Liang, Joshua, Clemens, Ralf
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/54649
Resumo: Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
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spelling Bravo, LuluSmolenov, IgorHan, Htay HtayLi, PingHosain, RomanaRockhold, FrankClemens, Sue Ann CostaRoa Jr, CamiloBorja-Tabora, CharissaQuinsaat, AntoinetteLopez, PioLópez-Medina, EduardoBrochado, LeonardoHernández, Eder A.Reynales, HumbertoMedina, TatianaVelasquez, HectorToloza, Leonardo BautistaRodriguez, Edith JohanaSalazar, Dora Ines Molina deRodríguez, Camilo A.Sprinz, EduardoCerbino-Neto, JoséLuz, Kleber GiovanniSchwarzbold, Alexandre VargasPaiva, Maria SanaliCarlos, JosefinaMontellano, May Emmeline B.Los Reyes, Mari Rose A. deYu, Charles Y.Alberto, Edison R.Panaligan, Mario M.Salvani-Bautista, MilagrosBuntinx, ErikHites, MayaMartinot, Jean-BenoitBhorat, Qasim E.Badat, AyshaBaccarini, CarmenHu, BrandaJurgens, JacoEngelbrecht, JanAmbrosino, DonnaRichmond, PeterSiber, GeorgeLiang, JoshuaClemens, Ralf2022-08-16T11:20:00Z2022-08-16T11:20:00Z2022BRAVO, Lulu et al. Efficacy of the adjuvanted subunit protein COVID-19 vaccine, SCB-2019: a phase 2 and 3 multicentre, double-blind, randomised, placebo-controlled trial. Lancet, v. 399, p. 461-472, 20221474-547Xhttps://www.arca.fiocruz.br/handle/icict/5464910.1016/S0140-6736(22)00055-1Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.University of the Philippines Manila. Ermita, Manila, Philippines.Clover Biopharmaceuticals. Cambridge, MA, USA.Clover Biopharmaceuticals. Cambridge, MA, USA.Clover Biopharmaceuticals. Cambridge, MA, USA.Clover Biopharmaceuticals. Cambridge, MA, USA.Duke University Medical Center. Duke University Clinical Research Institute. Durham, NC, USA.University of Oxford. Oxford Vaccine Group. Oxford, UK.Manila Doctors Hospital. Manila, Philippines.Asian Hospital and Medical Center. Alabang, Muntinlupa, Philippines.Global Research in Infectious Diseases. Singapore.Universidad Del Valle Clínica Imbanaco. Centro de Estudios en Infectología Pediátrica. Cali, Colombia.Universidad Del Valle Clínica Imbanaco. Centro de Estudios en Infectología Pediátrica. Cali, Colombia.Clinica De La Costa. Barranquilla, Atlantico, Colombia.Hospital Universidad del Norte. Barranquilla, Colombia.Center of Attention in Medical Research. Bogotá, Colombia.Center of Attention in Medical Research. Bogotá, Colombia.Center of Attention in Medical Research. Bogotá, Colombia.Center of Attention in Medical Research. Bogotá, Colombia.Center of Attention in Medical Research. Bogotá, Colombia.Faculty of Health Sciences at the University of Caldas. Manizales, Colombia.Policlínico Social del Norte. Bogotá, Colombia.Federal University of Rio Grande do Sul. Hospital de Clinicas de Porto Alegre. Porto Alegre, RS, Brazil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil / D'Or Institute for Research and Education. Rio de Janeiro, RJ, Brazil.Federal University of Rio Grande do Norte. Natal, RN,Brazil.Universidade Federal de Santa Maria. Infectious Diseases Division. Rio Grande do Sul, Brazil.Atena Institute of Clinical Research. Natal, RN, Brazil.University of the East Ramon Magsaysay Memorial Medical Center. Quezon City, Philippines.Far Eastern University Hospital - Nicanor Reyes Medical Foundation. Quezon City, Philippines.Las Pinas Doctors Hospital. Las Pinas City, Philippines.De La Salle Medical and Health Sciences Institute. Cavite City, Philippines.Tropical Disease Foundation. Cavite City, Philippines.St Luke's Medical Center. Infection Control Service. Taguig, Philippines.University of the East Ramon Magsaysay Memorial Medical Center. Quezon City, Philippines.Anima Research Center. Alken, Belgium.Clinic of Infectious Diseases. CUB-Hôpital Erasme. Bruxelles, Belgium.CHU Universite Catholique de Louvain Namur Site Sainte-Elisabeth. Pulmonology Department. Namur, Belgium.Soweto Clinical Trials Centre. Johannesburg, South Africa.Wits Clinical Research. Soweto, Johannesburg, South Africa.Clover Biopharmaceuticals. Cambridge, MA, USA.Clover Biopharmaceuticals. Cambridge, MA, USA.DJW Research. Krugersdorp, Gauteng, South Africa.Dr JM Engelbrecht Trial Site. Vergelegen Mediclinic. Western Cape, South Africa.Independent Advisor. Stuart, FL, USA.University of Western Australia. Division of Paediatrics. Wesfarmers Centre of Vaccines. Perth, WA, Australia / Telethon Kids Institute. Infectious Diseases. Perth, WA, Australia / Perth. Children's Hospital. Perth, WA, Australia.Independent Advisor. New York, NY, USA.Clover Biopharmaceuticals. Chengdu, China.Global Research in Infectious Diseases. Rio de Janeiro, RJ, Brazil.engEfficacy of the adjuvanted subunit protein COVID-19 vaccine, SCB-2019: a phase 2 and 3 multicentre, double-blind, randomised, placebo-controlled trialinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleCOVID-19Vaccine SCB-2019SARS-CoV-2info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-83099https://www.arca.fiocruz.br/bitstream/icict/54649/1/license.txt586c046dcfeef936e32f0323bb9a47c0MD51ORIGINALEfficacy_Jose_Cerbino_etal_INI_2022.pdfEfficacy_Jose_Cerbino_etal_INI_2022.pdfapplication/pdf457359https://www.arca.fiocruz.br/bitstream/icict/54649/2/Efficacy_Jose_Cerbino_etal_INI_2022.pdff8becb1ede66dccf6cccb047b9da9bdeMD52icict/546492023-02-15 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dc.title.pt_BR.fl_str_mv Efficacy of the adjuvanted subunit protein COVID-19 vaccine, SCB-2019: a phase 2 and 3 multicentre, double-blind, randomised, placebo-controlled trial
title Efficacy of the adjuvanted subunit protein COVID-19 vaccine, SCB-2019: a phase 2 and 3 multicentre, double-blind, randomised, placebo-controlled trial
spellingShingle Efficacy of the adjuvanted subunit protein COVID-19 vaccine, SCB-2019: a phase 2 and 3 multicentre, double-blind, randomised, placebo-controlled trial
Bravo, Lulu
COVID-19
Vaccine SCB-2019
SARS-CoV-2
title_short Efficacy of the adjuvanted subunit protein COVID-19 vaccine, SCB-2019: a phase 2 and 3 multicentre, double-blind, randomised, placebo-controlled trial
title_full Efficacy of the adjuvanted subunit protein COVID-19 vaccine, SCB-2019: a phase 2 and 3 multicentre, double-blind, randomised, placebo-controlled trial
title_fullStr Efficacy of the adjuvanted subunit protein COVID-19 vaccine, SCB-2019: a phase 2 and 3 multicentre, double-blind, randomised, placebo-controlled trial
title_full_unstemmed Efficacy of the adjuvanted subunit protein COVID-19 vaccine, SCB-2019: a phase 2 and 3 multicentre, double-blind, randomised, placebo-controlled trial
title_sort Efficacy of the adjuvanted subunit protein COVID-19 vaccine, SCB-2019: a phase 2 and 3 multicentre, double-blind, randomised, placebo-controlled trial
author Bravo, Lulu
author_facet Bravo, Lulu
Smolenov, Igor
Han, Htay Htay
Li, Ping
Hosain, Romana
Rockhold, Frank
Clemens, Sue Ann Costa
Roa Jr, Camilo
Borja-Tabora, Charissa
Quinsaat, Antoinette
Lopez, Pio
López-Medina, Eduardo
Brochado, Leonardo
Hernández, Eder A.
Reynales, Humberto
Medina, Tatiana
Velasquez, Hector
Toloza, Leonardo Bautista
Rodriguez, Edith Johana
Salazar, Dora Ines Molina de
Rodríguez, Camilo A.
Sprinz, Eduardo
Cerbino-Neto, José
Luz, Kleber Giovanni
Schwarzbold, Alexandre Vargas
Paiva, Maria Sanali
Carlos, Josefina
Montellano, May Emmeline B.
Los Reyes, Mari Rose A. de
Yu, Charles Y.
Alberto, Edison R.
Panaligan, Mario M.
Salvani-Bautista, Milagros
Buntinx, Erik
Hites, Maya
Martinot, Jean-Benoit
Bhorat, Qasim E.
Badat, Aysha
Baccarini, Carmen
Hu, Branda
Jurgens, Jaco
Engelbrecht, Jan
Ambrosino, Donna
Richmond, Peter
Siber, George
Liang, Joshua
Clemens, Ralf
author_role author
author2 Smolenov, Igor
Han, Htay Htay
Li, Ping
Hosain, Romana
Rockhold, Frank
Clemens, Sue Ann Costa
Roa Jr, Camilo
Borja-Tabora, Charissa
Quinsaat, Antoinette
Lopez, Pio
López-Medina, Eduardo
Brochado, Leonardo
Hernández, Eder A.
Reynales, Humberto
Medina, Tatiana
Velasquez, Hector
Toloza, Leonardo Bautista
Rodriguez, Edith Johana
Salazar, Dora Ines Molina de
Rodríguez, Camilo A.
Sprinz, Eduardo
Cerbino-Neto, José
Luz, Kleber Giovanni
Schwarzbold, Alexandre Vargas
Paiva, Maria Sanali
Carlos, Josefina
Montellano, May Emmeline B.
Los Reyes, Mari Rose A. de
Yu, Charles Y.
Alberto, Edison R.
Panaligan, Mario M.
Salvani-Bautista, Milagros
Buntinx, Erik
Hites, Maya
Martinot, Jean-Benoit
Bhorat, Qasim E.
Badat, Aysha
Baccarini, Carmen
Hu, Branda
Jurgens, Jaco
Engelbrecht, Jan
Ambrosino, Donna
Richmond, Peter
Siber, George
Liang, Joshua
Clemens, Ralf
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Bravo, Lulu
Smolenov, Igor
Han, Htay Htay
Li, Ping
Hosain, Romana
Rockhold, Frank
Clemens, Sue Ann Costa
Roa Jr, Camilo
Borja-Tabora, Charissa
Quinsaat, Antoinette
Lopez, Pio
López-Medina, Eduardo
Brochado, Leonardo
Hernández, Eder A.
Reynales, Humberto
Medina, Tatiana
Velasquez, Hector
Toloza, Leonardo Bautista
Rodriguez, Edith Johana
Salazar, Dora Ines Molina de
Rodríguez, Camilo A.
Sprinz, Eduardo
Cerbino-Neto, José
Luz, Kleber Giovanni
Schwarzbold, Alexandre Vargas
Paiva, Maria Sanali
Carlos, Josefina
Montellano, May Emmeline B.
Los Reyes, Mari Rose A. de
Yu, Charles Y.
Alberto, Edison R.
Panaligan, Mario M.
Salvani-Bautista, Milagros
Buntinx, Erik
Hites, Maya
Martinot, Jean-Benoit
Bhorat, Qasim E.
Badat, Aysha
Baccarini, Carmen
Hu, Branda
Jurgens, Jaco
Engelbrecht, Jan
Ambrosino, Donna
Richmond, Peter
Siber, George
Liang, Joshua
Clemens, Ralf
dc.subject.en.pt_BR.fl_str_mv COVID-19
Vaccine SCB-2019
SARS-CoV-2
topic COVID-19
Vaccine SCB-2019
SARS-CoV-2
description Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
publishDate 2022
dc.date.accessioned.fl_str_mv 2022-08-16T11:20:00Z
dc.date.available.fl_str_mv 2022-08-16T11:20:00Z
dc.date.issued.fl_str_mv 2022
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv BRAVO, Lulu et al. Efficacy of the adjuvanted subunit protein COVID-19 vaccine, SCB-2019: a phase 2 and 3 multicentre, double-blind, randomised, placebo-controlled trial. Lancet, v. 399, p. 461-472, 2022
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/54649
dc.identifier.issn.pt_BR.fl_str_mv 1474-547X
dc.identifier.doi.none.fl_str_mv 10.1016/S0140-6736(22)00055-1
identifier_str_mv BRAVO, Lulu et al. Efficacy of the adjuvanted subunit protein COVID-19 vaccine, SCB-2019: a phase 2 and 3 multicentre, double-blind, randomised, placebo-controlled trial. Lancet, v. 399, p. 461-472, 2022
1474-547X
10.1016/S0140-6736(22)00055-1
url https://www.arca.fiocruz.br/handle/icict/54649
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
bitstream.url.fl_str_mv https://www.arca.fiocruz.br/bitstream/icict/54649/1/license.txt
https://www.arca.fiocruz.br/bitstream/icict/54649/2/Efficacy_Jose_Cerbino_etal_INI_2022.pdf
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bitstream.checksumAlgorithm.fl_str_mv MD5
MD5
repository.name.fl_str_mv Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)
repository.mail.fl_str_mv repositorio.arca@fiocruz.br
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