Comparison of tests for the detection of circulating filarial antigen (Og4C3-ELISA and AD12-ICT) and ultrasound in diagnosis of lymphatic filariasis in individuals with microfilariae
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2009 |
| Outros Autores: | , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
| Texto Completo: | https://www.arca.fiocruz.br/handle/icict/27303 |
Resumo: | FIOCRUZ / FUNASA (projetos 268-369-433, sub-projeto 17), FIOTEC / SVS (projetos 573-17 e 801-17), Departamento de Parasitologia do Centro de Pesquisas Aggeu Magalhães |
| id |
CRUZ_0f7aba0251503d488888993f752a0611 |
|---|---|
| oai_identifier_str |
oai:www.arca.fiocruz.br:icict/27303 |
| network_acronym_str |
CRUZ |
| network_name_str |
Repositório Institucional da FIOCRUZ (ARCA) |
| repository_id_str |
2135 |
| spelling |
Rocha, AbrahamBraga, CynthiaBelém, MarcelaCarrera, ArturoAguiar-Santos, AnaOliveira, PaulaTexeira, Maria JoséFurtado, André2018-07-05T11:42:31Z2018-07-05T11:42:31Z2009ROCHA, A. et al. Comparison of tests for the detection of circulating filarial antigen (Og4C3-ELISA and AD12-ICT) and ultrasound in diagnosis of lymphatic filariasis in individuals with microfilariae. Memórias do Instituto Oswaldo Cruz, v. 104, n. 4, p. 621–625, jul. 2009.1678-8060https://www.arca.fiocruz.br/handle/icict/2730310.1590/S0074-02762009000400015FIOCRUZ / FUNASA (projetos 268-369-433, sub-projeto 17), FIOTEC / SVS (projetos 573-17 e 801-17), Departamento de Parasitologia do Centro de Pesquisas Aggeu MagalhãesFundação Oswaldo Cruz. Instituto Aggeu Magalhães. Serviço de Referência Nacional em Filarioses e Serviço de Referência em Culicídeos Vetores. Departamento de Parasitologia. Recife, PE, Brasil.Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Serviço de Referência Nacional em Filarioses e Serviço de Referência em Culicídeos Vetores. Departamento de Parasitologia. Recife, PE, Brasil.Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Serviço de Referência Nacional em Filarioses e Serviço de Referência em Culicídeos Vetores. Departamento de Parasitologia. Recife, PE, Brasil.Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Serviço de Referência Nacional em Filarioses e Serviço de Referência em Culicídeos Vetores. Departamento de Parasitologia. Recife, PE, Brasil.Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Serviço de Referência Nacional em Filarioses e Serviço de Referência em Culicídeos Vetores. Departamento de Parasitologia. Recife, PE, Brasil.Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Serviço de Referência Nacional em Filarioses e Serviço de Referência em Culicídeos Vetores. Departamento de Parasitologia. Recife, PE, Brasil.Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Serviço de Referência Nacional em Filarioses e Serviço de Referência em Culicídeos Vetores. Departamento de Parasitologia. Recife, PE, Brasil.Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Departamento de Entomologia. Recife, PE, Brasil.Significant advances were made in the diagnosis of filariasis in the 1990s with the emergence of three new alternative tools: ultrasound and tests to detect circulating antigen using two monoclonal antibodies, Og4C3 and AD12-ICT-card. This study aimed to identify which of these methods is the most sensitive for diagnosis of infection. A total of 256 individuals, all male and carrying microfilariae (1-15,679 MF/mL), diagnosed by nocturnal venous blood samples, were tested by all three techniques. The tests for circulating filarial antigen concurred 100% and correctly identified 246/256 (96.69%) of the positive individuals, while ultrasound detected only 186/256 (73.44%). Of the circulating antigen tests, ICT-card was the most convenient method for identification of Wuchereria bancrofti carriers. It was easy to perform, practical and quick.engWuchereria bancroftiAntígeno filario circulanteUltrassonografiaDiagnósticoWuchereria bancroftiCirculating filarial antigenUltrasoundDiagnosisAdolescenteAdultoAnimaisIdosoAnticorpos, HelmintosAnticorpos MonoclonaisAntígenos, Helmintos / sangueCriançaElefantíase, filarial / sangueFilariose Linfática / diagnósticoElephantiasis, Filarial / diagnóstico por imagemEnsaio de Imunoadsorção EnzimáticaHumanosMasculinoMicrofilaria / ultraestruturaMeia idadeSensibilidade e EspecificidadeUltrassonografiaWuchereria bancrofti / imunologiaAdulto jovemComparison of tests for the detection of circulating filarial antigen (Og4C3-ELISA and AD12-ICT) and ultrasound in diagnosis of lymphatic filariasis in individuals with microfilariaeinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-83092https://www.arca.fiocruz.br/bitstream/icict/27303/1/license.txt447f2497af1ef5cf99b5c07f6fa18dceMD51ORIGINALComparison of tests for the detection of circulating filarial antigen.pdfComparison of tests for the detection of circulating filarial antigen.pdfapplication/pdf460142https://www.arca.fiocruz.br/bitstream/icict/27303/2/Comparison%20of%20tests%20for%20the%20detection%20of%20circulating%20filarial%20antigen.pdf459f78f379185c1592cf5d09b007de52MD52TEXTComparison of tests for the detection of circulating filarial antigen.pdf.txtComparison of tests for the detection of circulating filarial antigen.pdf.txtExtracted texttext/plain25946https://www.arca.fiocruz.br/bitstream/icict/27303/3/Comparison%20of%20tests%20for%20the%20detection%20of%20circulating%20filarial%20antigen.pdf.txt5f306a18c00f6cef4bc5d18f88d544ebMD53icict/273032018-08-15 03:35:34.759oai:www.arca.fiocruz.br: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Repositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352018-08-15T06:35:34Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false |
| dc.title.pt_BR.fl_str_mv |
Comparison of tests for the detection of circulating filarial antigen (Og4C3-ELISA and AD12-ICT) and ultrasound in diagnosis of lymphatic filariasis in individuals with microfilariae |
| title |
Comparison of tests for the detection of circulating filarial antigen (Og4C3-ELISA and AD12-ICT) and ultrasound in diagnosis of lymphatic filariasis in individuals with microfilariae |
| spellingShingle |
Comparison of tests for the detection of circulating filarial antigen (Og4C3-ELISA and AD12-ICT) and ultrasound in diagnosis of lymphatic filariasis in individuals with microfilariae Rocha, Abraham Wuchereria bancrofti Antígeno filario circulante Ultrassonografia Diagnóstico Wuchereria bancrofti Circulating filarial antigen Ultrasound Diagnosis Adolescente Adulto Animais Idoso Anticorpos, Helmintos Anticorpos Monoclonais Antígenos, Helmintos / sangue Criança Elefantíase, filarial / sangue Filariose Linfática / diagnóstico Elephantiasis, Filarial / diagnóstico por imagem Ensaio de Imunoadsorção Enzimática Humanos Masculino Microfilaria / ultraestrutura Meia idade Sensibilidade e Especificidade Ultrassonografia Wuchereria bancrofti / imunologia Adulto jovem |
| title_short |
Comparison of tests for the detection of circulating filarial antigen (Og4C3-ELISA and AD12-ICT) and ultrasound in diagnosis of lymphatic filariasis in individuals with microfilariae |
| title_full |
Comparison of tests for the detection of circulating filarial antigen (Og4C3-ELISA and AD12-ICT) and ultrasound in diagnosis of lymphatic filariasis in individuals with microfilariae |
| title_fullStr |
Comparison of tests for the detection of circulating filarial antigen (Og4C3-ELISA and AD12-ICT) and ultrasound in diagnosis of lymphatic filariasis in individuals with microfilariae |
| title_full_unstemmed |
Comparison of tests for the detection of circulating filarial antigen (Og4C3-ELISA and AD12-ICT) and ultrasound in diagnosis of lymphatic filariasis in individuals with microfilariae |
| title_sort |
Comparison of tests for the detection of circulating filarial antigen (Og4C3-ELISA and AD12-ICT) and ultrasound in diagnosis of lymphatic filariasis in individuals with microfilariae |
| author |
Rocha, Abraham |
| author_facet |
Rocha, Abraham Braga, Cynthia Belém, Marcela Carrera, Arturo Aguiar-Santos, Ana Oliveira, Paula Texeira, Maria José Furtado, André |
| author_role |
author |
| author2 |
Braga, Cynthia Belém, Marcela Carrera, Arturo Aguiar-Santos, Ana Oliveira, Paula Texeira, Maria José Furtado, André |
| author2_role |
author author author author author author author |
| dc.contributor.author.fl_str_mv |
Rocha, Abraham Braga, Cynthia Belém, Marcela Carrera, Arturo Aguiar-Santos, Ana Oliveira, Paula Texeira, Maria José Furtado, André |
| dc.subject.other.pt_BR.fl_str_mv |
Wuchereria bancrofti Antígeno filario circulante Ultrassonografia Diagnóstico |
| topic |
Wuchereria bancrofti Antígeno filario circulante Ultrassonografia Diagnóstico Wuchereria bancrofti Circulating filarial antigen Ultrasound Diagnosis Adolescente Adulto Animais Idoso Anticorpos, Helmintos Anticorpos Monoclonais Antígenos, Helmintos / sangue Criança Elefantíase, filarial / sangue Filariose Linfática / diagnóstico Elephantiasis, Filarial / diagnóstico por imagem Ensaio de Imunoadsorção Enzimática Humanos Masculino Microfilaria / ultraestrutura Meia idade Sensibilidade e Especificidade Ultrassonografia Wuchereria bancrofti / imunologia Adulto jovem |
| dc.subject.en.pt_BR.fl_str_mv |
Wuchereria bancrofti Circulating filarial antigen Ultrasound Diagnosis |
| dc.subject.decs.pt_BR.fl_str_mv |
Adolescente Adulto Animais Idoso Anticorpos, Helmintos Anticorpos Monoclonais Antígenos, Helmintos / sangue Criança Elefantíase, filarial / sangue Filariose Linfática / diagnóstico Elephantiasis, Filarial / diagnóstico por imagem Ensaio de Imunoadsorção Enzimática Humanos Masculino Microfilaria / ultraestrutura Meia idade Sensibilidade e Especificidade Ultrassonografia Wuchereria bancrofti / imunologia Adulto jovem |
| description |
FIOCRUZ / FUNASA (projetos 268-369-433, sub-projeto 17), FIOTEC / SVS (projetos 573-17 e 801-17), Departamento de Parasitologia do Centro de Pesquisas Aggeu Magalhães |
| publishDate |
2009 |
| dc.date.issued.fl_str_mv |
2009 |
| dc.date.accessioned.fl_str_mv |
2018-07-05T11:42:31Z |
| dc.date.available.fl_str_mv |
2018-07-05T11:42:31Z |
| dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
| dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
| format |
article |
| status_str |
publishedVersion |
| dc.identifier.citation.fl_str_mv |
ROCHA, A. et al. Comparison of tests for the detection of circulating filarial antigen (Og4C3-ELISA and AD12-ICT) and ultrasound in diagnosis of lymphatic filariasis in individuals with microfilariae. Memórias do Instituto Oswaldo Cruz, v. 104, n. 4, p. 621–625, jul. 2009. |
| dc.identifier.uri.fl_str_mv |
https://www.arca.fiocruz.br/handle/icict/27303 |
| dc.identifier.issn.pt_BR.fl_str_mv |
1678-8060 |
| dc.identifier.doi.none.fl_str_mv |
10.1590/S0074-02762009000400015 |
| identifier_str_mv |
ROCHA, A. et al. Comparison of tests for the detection of circulating filarial antigen (Og4C3-ELISA and AD12-ICT) and ultrasound in diagnosis of lymphatic filariasis in individuals with microfilariae. Memórias do Instituto Oswaldo Cruz, v. 104, n. 4, p. 621–625, jul. 2009. 1678-8060 10.1590/S0074-02762009000400015 |
| url |
https://www.arca.fiocruz.br/handle/icict/27303 |
| dc.language.iso.fl_str_mv |
eng |
| language |
eng |
| dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
| eu_rights_str_mv |
openAccess |
| dc.source.none.fl_str_mv |
reponame:Repositório Institucional da FIOCRUZ (ARCA) instname:Fundação Oswaldo Cruz (FIOCRUZ) instacron:FIOCRUZ |
| instname_str |
Fundação Oswaldo Cruz (FIOCRUZ) |
| instacron_str |
FIOCRUZ |
| institution |
FIOCRUZ |
| reponame_str |
Repositório Institucional da FIOCRUZ (ARCA) |
| collection |
Repositório Institucional da FIOCRUZ (ARCA) |
| bitstream.url.fl_str_mv |
https://www.arca.fiocruz.br/bitstream/icict/27303/1/license.txt https://www.arca.fiocruz.br/bitstream/icict/27303/2/Comparison%20of%20tests%20for%20the%20detection%20of%20circulating%20filarial%20antigen.pdf https://www.arca.fiocruz.br/bitstream/icict/27303/3/Comparison%20of%20tests%20for%20the%20detection%20of%20circulating%20filarial%20antigen.pdf.txt |
| bitstream.checksum.fl_str_mv |
447f2497af1ef5cf99b5c07f6fa18dce 459f78f379185c1592cf5d09b007de52 5f306a18c00f6cef4bc5d18f88d544eb |
| bitstream.checksumAlgorithm.fl_str_mv |
MD5 MD5 MD5 |
| repository.name.fl_str_mv |
Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ) |
| repository.mail.fl_str_mv |
repositorio.arca@fiocruz.br |
| _version_ |
1798325074894258176 |