Genomic Epidemiology and Lineage Dynamics of SARS-CoV-2 in Bulgaria: Insights from a Three-Year Pandemic Analysis

Detalhes bibliográficos
Autor(a) principal: Giovanetti, Marta
Data de Publicação: 2023
Outros Autores: Cella, Eleonora, Ivanov, Ivan, Grigorova, Lyubomira, Stoikov, Ivan, Donchev, Deyan, Dimitrova, Reneta, Slavov, Svetoslav Nanev, Mavian, Carla, Fonseca, Vagner, Scarpa, Fabio, Borsetti, Alessandra, Korsun, Neli, Trifonova, Ivelina, Dobrinov, Veselin, Kantardjiev, Todor, Christova, Iva, Ciccozzi, Massimo, Alexiev, Ivailo
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/61085
Resumo: Fundação Oswaldo Cruz. Instituto Rene Rachou. Belo Horizonte. MG, Brazil / Sciences and Technologies for Sustainable Development and One Health. Università Campus Bio-Medico di Roma. Rome, Italy / Climate Amplified Diseases and Epidemics. Brazil.
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spelling Giovanetti, MartaCella, EleonoraIvanov, IvanGrigorova, LyubomiraStoikov, IvanDonchev, DeyanDimitrova, RenetaSlavov, Svetoslav NanevMavian, CarlaFonseca, VagnerScarpa, FabioBorsetti, AlessandraKorsun, NeliTrifonova, IvelinaDobrinov, VeselinKantardjiev, TodorChristova, IvaCiccozzi, MassimoAlexiev, Ivailo2023-11-07T19:20:26Z2023-11-07T19:20:26Z2023GIOVANETTI, Marta et al. Genomic Epidemiology and Lineage Dynamics of SARS-CoV-2 in Bulgaria: Insights from a Three-Year Pandemic Analysis. Viruses, v. 15, n. 9, p. 1-11, 2023.1999-4915https://www.arca.fiocruz.br/handle/icict/6108510.3390/v15091924engMPDIGenomic Epidemiology and Lineage Dynamics of SARS-CoV-2 in Bulgaria: Insights from a Three-Year Pandemic Analysisinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Rene Rachou. Belo Horizonte. MG, Brazil / Sciences and Technologies for Sustainable Development and One Health. Università Campus Bio-Medico di Roma. Rome, Italy / Climate Amplified Diseases and Epidemics. Brazil.Burnett School of Biomedical Sciences. University of Central Florida. Orlando, FL, USA.National Center of Infectious and Parasitic Diseases. Sofia, Bulgaria.National Center of Infectious and Parasitic Diseases. Sofia, Bulgaria.National Center of Infectious and Parasitic Diseases. Sofia, Bulgaria.National Center of Infectious and Parasitic Diseases. Sofia, Bulgaria.National Center of Infectious and Parasitic Diseases. Sofia, Bulgaria.Butantan Institute. São Paulo, SP, Brazil / Blood Center of Ribeirão Preto. Faculty of Medicine of Ribeirão Preto. University of São Paulo. Ribeirão Preto, SP, Brazil.Emerging Pathogens Institute. Department of Pathology, Immunology and Laboratory Medicine. College of Medicine. University of Florida. Gainesville, FL, USA.Department of Exact and Earth Sciences. University of the State of Bahia. Salvador BA, Brazil / Organização Pan-Americana da Saúde/Organização Mundial da Saúde. Coordenação de Vigilância, Preparação e Resposta à Emergências e Desastres. Brasilia, DF, Brazil.Department of Biomedical Sciences. University of Sassari. Sassari, Italy.National HIV/AIDS Research Center. National Institute of Health. Rome, Italy.National Center of Infectious and Parasitic Diseases. Sofia, Bulgaria.National Center of Infectious and Parasitic Diseases. Sofia, Bulgaria.National Center of Infectious and Parasitic Diseases. Sofia, Bulgaria.National Center of Infectious and Parasitic Diseases. Sofia, Bulgaria.National Center of Infectious and Parasitic Diseases. Sofia, Bulgaria.Unit of Medical Statistics and Molecular Epidemiology. Universita Campus Bio-Medico di Roma. Rome, Italy.National Center of Infectious and Parasitic Diseases. Sofia, Bulgaria.The COVID-19 pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has brought about significant challenges worldwide. In this study, we present a comprehensive analysis of the genomic epidemiology and lineage dynamics of SARS-CoV-2 in Bulgaria over a three-year period. Through extensive genomic sequencing and data analysis, we investigated the evolution of the virus, the emergence of variants of concern (VOCs), and their impact on the country's pandemic trajectory. We also assessed the relationship between viral diversity and COVID-19 morbidity and mortality in Bulgaria. Our findings shed light on the temporal and spatial distribution of SARS-CoV-2 lineages and provide crucial insights into the dynamics of the pandemic in the country. The interplay between international travel and viral transmission plays a significant role in the emergence and dissemination of different SARS-CoV-2 variants. The observed proportions of exportation to various continents provide insights into the potential pathways through which these lineages spread globally. Understanding the genomic epidemiology of SARS-CoV-2 in Bulgaria is essential for formulating targeted public health strategies, enhancing vaccination efforts, and effectively managing future outbreaks.BulgariaSARS-CoV-2EpidemiologyGenomic surveillanceViral evolutionCOVID-19info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/61085/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALGenomic Epidemiology and Lineage Dynamics of SARS-CoV-2 in Bulgaria_ Insights from a Three-Year Pandemic Analysis.pdfGenomic Epidemiology and Lineage Dynamics of SARS-CoV-2 in Bulgaria_ Insights from a Three-Year Pandemic Analysis.pdfapplication/pdf3163094https://www.arca.fiocruz.br/bitstream/icict/61085/2/Genomic%20Epidemiology%20and%20Lineage%20Dynamics%20of%20SARS-CoV-2%20in%20Bulgaria_%20Insights%20from%20a%20Three-Year%20Pandemic%20Analysis.pdf3b919500125350ae4f69750a77c178fbMD52icict/610852023-11-07 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dc.title.en_US.fl_str_mv Genomic Epidemiology and Lineage Dynamics of SARS-CoV-2 in Bulgaria: Insights from a Three-Year Pandemic Analysis
title Genomic Epidemiology and Lineage Dynamics of SARS-CoV-2 in Bulgaria: Insights from a Three-Year Pandemic Analysis
spellingShingle Genomic Epidemiology and Lineage Dynamics of SARS-CoV-2 in Bulgaria: Insights from a Three-Year Pandemic Analysis
Giovanetti, Marta
Bulgaria
SARS-CoV-2
Epidemiology
Genomic surveillance
Viral evolution
COVID-19
title_short Genomic Epidemiology and Lineage Dynamics of SARS-CoV-2 in Bulgaria: Insights from a Three-Year Pandemic Analysis
title_full Genomic Epidemiology and Lineage Dynamics of SARS-CoV-2 in Bulgaria: Insights from a Three-Year Pandemic Analysis
title_fullStr Genomic Epidemiology and Lineage Dynamics of SARS-CoV-2 in Bulgaria: Insights from a Three-Year Pandemic Analysis
title_full_unstemmed Genomic Epidemiology and Lineage Dynamics of SARS-CoV-2 in Bulgaria: Insights from a Three-Year Pandemic Analysis
title_sort Genomic Epidemiology and Lineage Dynamics of SARS-CoV-2 in Bulgaria: Insights from a Three-Year Pandemic Analysis
author Giovanetti, Marta
author_facet Giovanetti, Marta
Cella, Eleonora
Ivanov, Ivan
Grigorova, Lyubomira
Stoikov, Ivan
Donchev, Deyan
Dimitrova, Reneta
Slavov, Svetoslav Nanev
Mavian, Carla
Fonseca, Vagner
Scarpa, Fabio
Borsetti, Alessandra
Korsun, Neli
Trifonova, Ivelina
Dobrinov, Veselin
Kantardjiev, Todor
Christova, Iva
Ciccozzi, Massimo
Alexiev, Ivailo
author_role author
author2 Cella, Eleonora
Ivanov, Ivan
Grigorova, Lyubomira
Stoikov, Ivan
Donchev, Deyan
Dimitrova, Reneta
Slavov, Svetoslav Nanev
Mavian, Carla
Fonseca, Vagner
Scarpa, Fabio
Borsetti, Alessandra
Korsun, Neli
Trifonova, Ivelina
Dobrinov, Veselin
Kantardjiev, Todor
Christova, Iva
Ciccozzi, Massimo
Alexiev, Ivailo
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Giovanetti, Marta
Cella, Eleonora
Ivanov, Ivan
Grigorova, Lyubomira
Stoikov, Ivan
Donchev, Deyan
Dimitrova, Reneta
Slavov, Svetoslav Nanev
Mavian, Carla
Fonseca, Vagner
Scarpa, Fabio
Borsetti, Alessandra
Korsun, Neli
Trifonova, Ivelina
Dobrinov, Veselin
Kantardjiev, Todor
Christova, Iva
Ciccozzi, Massimo
Alexiev, Ivailo
dc.subject.en.en_US.fl_str_mv Bulgaria
SARS-CoV-2
Epidemiology
Genomic surveillance
Viral evolution
topic Bulgaria
SARS-CoV-2
Epidemiology
Genomic surveillance
Viral evolution
COVID-19
dc.subject.en.none.fl_str_mv COVID-19
description Fundação Oswaldo Cruz. Instituto Rene Rachou. Belo Horizonte. MG, Brazil / Sciences and Technologies for Sustainable Development and One Health. Università Campus Bio-Medico di Roma. Rome, Italy / Climate Amplified Diseases and Epidemics. Brazil.
publishDate 2023
dc.date.accessioned.fl_str_mv 2023-11-07T19:20:26Z
dc.date.available.fl_str_mv 2023-11-07T19:20:26Z
dc.date.issued.fl_str_mv 2023
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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status_str publishedVersion
dc.identifier.citation.fl_str_mv GIOVANETTI, Marta et al. Genomic Epidemiology and Lineage Dynamics of SARS-CoV-2 in Bulgaria: Insights from a Three-Year Pandemic Analysis. Viruses, v. 15, n. 9, p. 1-11, 2023.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/61085
dc.identifier.issn.en_US.fl_str_mv 1999-4915
dc.identifier.doi.none.fl_str_mv 10.3390/v15091924
identifier_str_mv GIOVANETTI, Marta et al. Genomic Epidemiology and Lineage Dynamics of SARS-CoV-2 in Bulgaria: Insights from a Three-Year Pandemic Analysis. Viruses, v. 15, n. 9, p. 1-11, 2023.
1999-4915
10.3390/v15091924
url https://www.arca.fiocruz.br/handle/icict/61085
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv MPDI
publisher.none.fl_str_mv MPDI
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
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bitstream.url.fl_str_mv https://www.arca.fiocruz.br/bitstream/icict/61085/1/license.txt
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