Are there differences in clinical and laboratory parameters between children and adults with American visceral leishmaniasis?

Detalhes bibliográficos
Autor(a) principal: Caldas, Arlene de Jesus Mendes
Data de Publicação: 2006
Outros Autores: Costa, Jackson Mauricio Lopes, Aquino, Dorlene Maria Cardoso de, Silva, Antonio Augusto Moura da, Barral Netto, Manoel, Barral, Aldina Maria Prado
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/2746
Resumo: Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil
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spelling Caldas, Arlene de Jesus MendesCosta, Jackson Mauricio LopesAquino, Dorlene Maria Cardoso deSilva, Antonio Augusto Moura daBarral Netto, ManoelBarral, Aldina Maria Prado2011-07-04T18:44:37Z2011-07-04T18:44:37Z2006CALDAS, A. J. M. et al. Are there differences in clinical and laboratory parameters between children and adults with American visceral leishmaniasis? Acta Tropica, v.97, n.3, p.252-258, 2006.0001-706Xhttps://www.arca.fiocruz.br/handle/icict/274610.1016/j.actatropica.2005.09.010porLeishmaniose Visceral AmericanaCriançasAdultosHipersensibilidade tardiaResposta LinfoproliferativaAmerican Visceral LeishmaniasisChildrenAdultsDelayed-type HypersensitivityLymphoproliferative ResponseLeishmaniose VisceralCriançaAdultoHipersensibilidade TardiaAre there differences in clinical and laboratory parameters between children and adults with American visceral leishmaniasis?info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, BrasilUniversidade Federal do Maranhão. Departamento de Enfermagem. São Luís, MA, BrasilFundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, BrasilFundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, BrasilUniversidade Federal do Maranhão. Departamento de Enfermagem. São Luís, MA, BrasilUniversidade Federal do Maranhão. Departamento de Saúde Pública. São Luís, MA, BrasilFundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, BrasilUniversidade Federal da Bahia. Faculdade de Medicina da Bahia. Salvador, BA, BrasilFundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, BrasilUniversidade Federal da Bahia. Faculdade de Medicina da Bahia. Salvador, BA, BrasilAprospective study on 23 patients with American visceral leishmaniasis (VL), comparing clinical and laboratory parameters of 14 children (mean age of 3.85±3.39 years) to nine adults (27.4±10.90 years) was performed in S˜ao Lu´ıs, Maranh˜ao, Brazil, between August 2000 and July 2002. Data were collected at entrance (day 0), end of treatment, as well as 120 and 210 days after treatment using a protocol chart containing patient identification, clinical and laboratory data. N-Methylglucamine antimonate administered at the dose of 20 mg/Sb5+/kg/day for 20–30 days was successfully used in all patients. Patients were followed for 1 year after treatment, and no relapses were observed. A prolonged duration of the disease, lymphadenopathy and bleeding predominated in adult patients, while hepatomegaly and skin-mucosal pallor were more frequent in children. Disease was longer and more severe in adults than in children. Although both groups exhibited a trend toward normalization of hematological and biochemical parameters, more children returned sooner to normal values than adults. Difference in clinical or laboratory parameters between children and adults did not indicate the need for different clinical or therapeutic approaches.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZORIGINALCaldas_Costa_Aquino_etal.pdfCaldas_Costa_Aquino_etal.pdfapplication/pdf120494https://www.arca.fiocruz.br/bitstream/icict/2746/1/Caldas_Costa_Aquino_etal.pdf2a9b8887a2cdc44b56a6bd2385fb40e8MD51LICENSElicense.txtlicense.txttext/plain; charset=utf-81648https://www.arca.fiocruz.br/bitstream/icict/2746/2/license.txte095249ac7cacefbfe39684dfe45e706MD52TEXTCaldas_Costa_Aquino_etal.pdf.txtCaldas_Costa_Aquino_etal.pdf.txtExtracted texttext/plain30390https://www.arca.fiocruz.br/bitstream/icict/2746/5/Caldas_Costa_Aquino_etal.pdf.txtf364e52585d0f6b25424e8c3d131b2e5MD55THUMBNAILCaldas_Costa_Aquino_etal.pdf.jpgCaldas_Costa_Aquino_etal.pdf.jpgGenerated Thumbnailimage/jpeg1312https://www.arca.fiocruz.br/bitstream/icict/2746/4/Caldas_Costa_Aquino_etal.pdf.jpg3d966b59d41028684103b59b5c06e2a6MD54icict/27462023-03-15 14:32:59.98oai:www.arca.fiocruz.br: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Repositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352023-03-15T17:32:59Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.pt_BR.fl_str_mv Are there differences in clinical and laboratory parameters between children and adults with American visceral leishmaniasis?
title Are there differences in clinical and laboratory parameters between children and adults with American visceral leishmaniasis?
spellingShingle Are there differences in clinical and laboratory parameters between children and adults with American visceral leishmaniasis?
Caldas, Arlene de Jesus Mendes
Leishmaniose Visceral Americana
Crianças
Adultos
Hipersensibilidade tardia
Resposta Linfoproliferativa
American Visceral Leishmaniasis
Children
Adults
Delayed-type Hypersensitivity
Lymphoproliferative Response
Leishmaniose Visceral
Criança
Adulto
Hipersensibilidade Tardia
title_short Are there differences in clinical and laboratory parameters between children and adults with American visceral leishmaniasis?
title_full Are there differences in clinical and laboratory parameters between children and adults with American visceral leishmaniasis?
title_fullStr Are there differences in clinical and laboratory parameters between children and adults with American visceral leishmaniasis?
title_full_unstemmed Are there differences in clinical and laboratory parameters between children and adults with American visceral leishmaniasis?
title_sort Are there differences in clinical and laboratory parameters between children and adults with American visceral leishmaniasis?
author Caldas, Arlene de Jesus Mendes
author_facet Caldas, Arlene de Jesus Mendes
Costa, Jackson Mauricio Lopes
Aquino, Dorlene Maria Cardoso de
Silva, Antonio Augusto Moura da
Barral Netto, Manoel
Barral, Aldina Maria Prado
author_role author
author2 Costa, Jackson Mauricio Lopes
Aquino, Dorlene Maria Cardoso de
Silva, Antonio Augusto Moura da
Barral Netto, Manoel
Barral, Aldina Maria Prado
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Caldas, Arlene de Jesus Mendes
Costa, Jackson Mauricio Lopes
Aquino, Dorlene Maria Cardoso de
Silva, Antonio Augusto Moura da
Barral Netto, Manoel
Barral, Aldina Maria Prado
dc.subject.other.pt_BR.fl_str_mv Leishmaniose Visceral Americana
Crianças
Adultos
Hipersensibilidade tardia
Resposta Linfoproliferativa
topic Leishmaniose Visceral Americana
Crianças
Adultos
Hipersensibilidade tardia
Resposta Linfoproliferativa
American Visceral Leishmaniasis
Children
Adults
Delayed-type Hypersensitivity
Lymphoproliferative Response
Leishmaniose Visceral
Criança
Adulto
Hipersensibilidade Tardia
dc.subject.en.pt_BR.fl_str_mv American Visceral Leishmaniasis
Children
Adults
Delayed-type Hypersensitivity
Lymphoproliferative Response
dc.subject.decs.pt_BR.fl_str_mv Leishmaniose Visceral
Criança
Adulto
Hipersensibilidade Tardia
description Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil
publishDate 2006
dc.date.issued.fl_str_mv 2006
dc.date.accessioned.fl_str_mv 2011-07-04T18:44:37Z
dc.date.available.fl_str_mv 2011-07-04T18:44:37Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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dc.identifier.citation.fl_str_mv CALDAS, A. J. M. et al. Are there differences in clinical and laboratory parameters between children and adults with American visceral leishmaniasis? Acta Tropica, v.97, n.3, p.252-258, 2006.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/2746
dc.identifier.issn.none.fl_str_mv 0001-706X
dc.identifier.doi.none.fl_str_mv 10.1016/j.actatropica.2005.09.010
identifier_str_mv CALDAS, A. J. M. et al. Are there differences in clinical and laboratory parameters between children and adults with American visceral leishmaniasis? Acta Tropica, v.97, n.3, p.252-258, 2006.
0001-706X
10.1016/j.actatropica.2005.09.010
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