Local anaesthetic medication for the treatment of asthma

Detalhes bibliográficos
Autor(a) principal: Siqueira, Rodrigo A.
Data de Publicação: 2005
Outros Autores: Costa, Jorge C. S., Cordeiro, Renato S. B., Serra, Magda F., Silva, Patrícia M. R. e, Martins, Marco A.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/37829
Resumo: Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Fisiologia e Farmacodinâmica. Laboratório de Inflamação. Rio de Janeiro, RJ, Brasil.
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spelling Siqueira, Rodrigo A.Costa, Jorge C. S.Cordeiro, Renato S. B.Serra, Magda F.Silva, Patrícia M. R. eMartins, Marco A.2019-12-10T18:46:40Z2019-12-10T18:46:40Z2005SIQUEIRA, Rodrigo A. et al. Local anaesthetic medication for the treatment of asthma. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 100, Suppl. 1, p. 161-165, 2005.0074-0276https://www.arca.fiocruz.br/handle/icict/3782910.1590/S0074-027620050009000271678-8060engFundação Oswaldo Cruz. Instituto Oswaldo Cruz.Anestésico lovalLidocaínaInflamaçãoAsmaLocal anaestheticLidocaineInflammationAsthmaLocal anaesthetic medication for the treatment of asthmainfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Fisiologia e Farmacodinâmica. Laboratório de Inflamação. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Fisiologia e Farmacodinâmica. Laboratório de Inflamação. Rio de Janeiro, RJ, Brasil / Fundação Oswaldo Cruz. Farmanguinhos. Departamento de Síntese. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Fisiologia e Farmacodinâmica. Laboratório de Inflamação. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Fisiologia e Farmacodinâmica. Laboratório de Inflamação. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Fisiologia e Farmacodinâmica. Laboratório de Inflamação. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Fisiologia e Farmacodinâmica. Laboratório de Inflamação. Rio de Janeiro, RJ, Brasil.It is presumed that drugs able to prevent bronchial spasm and/or inflammation may have therapeutic potential to control asthma symptoms. The local anaesthetic lidocaine has recently received increased attention as an alternative form of treatment for asthmatic patients. This paper reviews the major findings on the topic and summarizes the putative mechanisms underlying the airway effects of local anaesthetic agents. We think that lidocaine extends the spectrum of options in asthma therapy, probably by counteracting both spasmogenic and inflammatory stimuli in the bronchial airways. The possibility of development of new anti-asthma compounds based on the synthesis of lidocaine derivatives is also on the horizon.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/37829/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALMarcoAMartins_RodrigoSiqueira_etal_IOC_2005.pdfMarcoAMartins_RodrigoSiqueira_etal_IOC_2005.pdfapplication/pdf33474https://www.arca.fiocruz.br/bitstream/icict/37829/2/MarcoAMartins_RodrigoSiqueira_etal_IOC_2005.pdfb9a1586f5b33e4d8635fc7b4f820f3b5MD52TEXTMarcoAMartins_RodrigoSiqueira_etal_IOC_2005.pdf.txtMarcoAMartins_RodrigoSiqueira_etal_IOC_2005.pdf.txtExtracted texttext/plain25143https://www.arca.fiocruz.br/bitstream/icict/37829/3/MarcoAMartins_RodrigoSiqueira_etal_IOC_2005.pdf.txt70b66af7488357e98ac4596f1ce010faMD53icict/378292019-12-13 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dc.title.pt_BR.fl_str_mv Local anaesthetic medication for the treatment of asthma
title Local anaesthetic medication for the treatment of asthma
spellingShingle Local anaesthetic medication for the treatment of asthma
Siqueira, Rodrigo A.
Anestésico loval
Lidocaína
Inflamação
Asma
Local anaesthetic
Lidocaine
Inflammation
Asthma
title_short Local anaesthetic medication for the treatment of asthma
title_full Local anaesthetic medication for the treatment of asthma
title_fullStr Local anaesthetic medication for the treatment of asthma
title_full_unstemmed Local anaesthetic medication for the treatment of asthma
title_sort Local anaesthetic medication for the treatment of asthma
author Siqueira, Rodrigo A.
author_facet Siqueira, Rodrigo A.
Costa, Jorge C. S.
Cordeiro, Renato S. B.
Serra, Magda F.
Silva, Patrícia M. R. e
Martins, Marco A.
author_role author
author2 Costa, Jorge C. S.
Cordeiro, Renato S. B.
Serra, Magda F.
Silva, Patrícia M. R. e
Martins, Marco A.
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Siqueira, Rodrigo A.
Costa, Jorge C. S.
Cordeiro, Renato S. B.
Serra, Magda F.
Silva, Patrícia M. R. e
Martins, Marco A.
dc.subject.other.pt_BR.fl_str_mv Anestésico loval
Lidocaína
Inflamação
Asma
topic Anestésico loval
Lidocaína
Inflamação
Asma
Local anaesthetic
Lidocaine
Inflammation
Asthma
dc.subject.en.pt_BR.fl_str_mv Local anaesthetic
Lidocaine
Inflammation
Asthma
description Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Fisiologia e Farmacodinâmica. Laboratório de Inflamação. Rio de Janeiro, RJ, Brasil.
publishDate 2005
dc.date.issued.fl_str_mv 2005
dc.date.accessioned.fl_str_mv 2019-12-10T18:46:40Z
dc.date.available.fl_str_mv 2019-12-10T18:46:40Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv SIQUEIRA, Rodrigo A. et al. Local anaesthetic medication for the treatment of asthma. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 100, Suppl. 1, p. 161-165, 2005.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/37829
dc.identifier.issn.pt_BR.fl_str_mv 0074-0276
dc.identifier.doi.none.fl_str_mv 10.1590/S0074-02762005000900027
dc.identifier.eissn.none.fl_str_mv 1678-8060
identifier_str_mv SIQUEIRA, Rodrigo A. et al. Local anaesthetic medication for the treatment of asthma. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 100, Suppl. 1, p. 161-165, 2005.
0074-0276
10.1590/S0074-02762005000900027
1678-8060
url https://www.arca.fiocruz.br/handle/icict/37829
dc.language.iso.fl_str_mv eng
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dc.publisher.none.fl_str_mv Fundação Oswaldo Cruz. Instituto Oswaldo Cruz.
publisher.none.fl_str_mv Fundação Oswaldo Cruz. Instituto Oswaldo Cruz.
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
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