Hematological Profile of Pregnant Women with Suspected Zika Virus Infection Followed Up at a Referral Service in Manaus, Brazil

Detalhes bibliográficos
Autor(a) principal: Andrade, Anny Beatriz Costa Antony de
Data de Publicação: 2021
Outros Autores: Gonçalves, Maria Jacirema Ferreira, Redivo, Elijane de Fátima, Alecrim, Maria das Graças Costa, Martinez-Espinosa, Flor Ernestina
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/56901
Resumo: Fundação de Medicina Tropical Dr. Heitor Vieira Dourado (FMT-HVD); Fundação de Amparo à Pesquisa do Estado do Amazonas (FAPEAM): Universal Amazonas, Programa Pró-Estado, Programa POSGRAD 2020; Ministério da Saúde do Brasil: Programa de Pesquisa para o SUS (PPSUS) e Departamento de Ciência e Tecnologia; Instituto Leônidas & Maria Deane (ILMD/Fiocruz Amazônia) em parceria com o Conselho Nacional de Desenvolvimento Científico e Tecnológico Desenvolvimento (CNPq) e parcialmente financiado pela Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES).
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spelling Andrade, Anny Beatriz Costa Antony deGonçalves, Maria Jacirema FerreiraRedivo, Elijane de FátimaAlecrim, Maria das Graças CostaMartinez-Espinosa, Flor Ernestina2023-02-06T19:51:00Z2023-02-06T19:51:00Z2021ANDRADE, Anny Beatriz Costa Antony de et al. Hematological Profile of Pregnant Women with Suspected Zika Virus Infection Followed Up at a Referral Service in Manaus, Brazil. Viruses, Basel, v. 13, n. 4, p. 1-11, 2021.1999-4915https://www.arca.fiocruz.br/handle/icict/5690110.3390/v13040710Fundação de Medicina Tropical Dr. Heitor Vieira Dourado (FMT-HVD); Fundação de Amparo à Pesquisa do Estado do Amazonas (FAPEAM): Universal Amazonas, Programa Pró-Estado, Programa POSGRAD 2020; Ministério da Saúde do Brasil: Programa de Pesquisa para o SUS (PPSUS) e Departamento de Ciência e Tecnologia; Instituto Leônidas & Maria Deane (ILMD/Fiocruz Amazônia) em parceria com o Conselho Nacional de Desenvolvimento Científico e Tecnológico Desenvolvimento (CNPq) e parcialmente financiado pela Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES).Fundação Oswaldo Cruz. Instituto Leônidas e Maria Deane. Manaus, AM, Brasil.Universidade Federal do Amazonas. Escola de Enfermagem. Manaus, AM, Brasil.Fundação de Medicina Tropical Dr. Heitor Vieira Dourado. Manaus, AM, Brasil.Fundação de Medicina Tropical Dr. Heitor Vieira Dourado. Manaus, AM, Brasil.Fundação Oswaldo Cruz. Instituto Leônidas e Maria Deane. Manaus, AM, Brasil.The purpose of this paper is to describe the hematological profile of pregnant women with suspected Zika virus (ZIKV) infection followed up at a reference service for infectious diseases in Manaus, Brazil, through a clinical, epidemiological, cross-sectional study of pregnant women with an exanthematic manifestation who looked for care between 2015 and 2017. The participants were 499 pregnant women, classified into four subgroups, according to laboratory confirmation of infections: ZIKV-positive; ZIKV-positive and positive for another infection; positive for another infection but not ZIKV-positive; and not positive for any of the infections investigated. Hematological parameters were analyzed descriptively. The association between maternal infection and the hematological profile, along with the association between the maternal hematological profile and the gestational outcome, were tested. Similar hematic and platelet parameters were observed among pregnant women. However, a significant association was observed between low maternal lymphocyte count and a positive diagnosis for ZIKV (p < 0.001). The increase in maternal platelet count and the occurrence of unfavorable gestational outcome were positively associated. A similar hematic and platelet profile was identified among pregnant women, differing only in the low lymphocyte count among ZIKV-positive pregnant women. Regarding gestational outcomes, in addition to the damage caused by ZIKV infection, altered maternal platelets may lead to unfavorable outcomes, with the need for adequate follow-up during prenatal care.engHematological Profile of Pregnant Women with Suspected Zika Virus Infection Followed Up at a Referral Service in Manaus, Brazilinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleArbovirusesZika virusPregnancyMaternal healthinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/56901/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALAndrade_Anny_etal_ILMD_2021.pdfAndrade_Anny_etal_ILMD_2021.pdfapplication/pdf482027https://www.arca.fiocruz.br/bitstream/icict/56901/2/Andrade_Anny_etal_ILMD_2021.pdf811b4d083027592eed5916e25d2595e0MD52icict/569012023-02-07 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dc.title.en_US.fl_str_mv Hematological Profile of Pregnant Women with Suspected Zika Virus Infection Followed Up at a Referral Service in Manaus, Brazil
title Hematological Profile of Pregnant Women with Suspected Zika Virus Infection Followed Up at a Referral Service in Manaus, Brazil
spellingShingle Hematological Profile of Pregnant Women with Suspected Zika Virus Infection Followed Up at a Referral Service in Manaus, Brazil
Andrade, Anny Beatriz Costa Antony de
Arboviruses
Zika virus
Pregnancy
Maternal health
title_short Hematological Profile of Pregnant Women with Suspected Zika Virus Infection Followed Up at a Referral Service in Manaus, Brazil
title_full Hematological Profile of Pregnant Women with Suspected Zika Virus Infection Followed Up at a Referral Service in Manaus, Brazil
title_fullStr Hematological Profile of Pregnant Women with Suspected Zika Virus Infection Followed Up at a Referral Service in Manaus, Brazil
title_full_unstemmed Hematological Profile of Pregnant Women with Suspected Zika Virus Infection Followed Up at a Referral Service in Manaus, Brazil
title_sort Hematological Profile of Pregnant Women with Suspected Zika Virus Infection Followed Up at a Referral Service in Manaus, Brazil
author Andrade, Anny Beatriz Costa Antony de
author_facet Andrade, Anny Beatriz Costa Antony de
Gonçalves, Maria Jacirema Ferreira
Redivo, Elijane de Fátima
Alecrim, Maria das Graças Costa
Martinez-Espinosa, Flor Ernestina
author_role author
author2 Gonçalves, Maria Jacirema Ferreira
Redivo, Elijane de Fátima
Alecrim, Maria das Graças Costa
Martinez-Espinosa, Flor Ernestina
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Andrade, Anny Beatriz Costa Antony de
Gonçalves, Maria Jacirema Ferreira
Redivo, Elijane de Fátima
Alecrim, Maria das Graças Costa
Martinez-Espinosa, Flor Ernestina
dc.subject.en.en_US.fl_str_mv Arboviruses
Zika virus
Pregnancy
Maternal health
topic Arboviruses
Zika virus
Pregnancy
Maternal health
description Fundação de Medicina Tropical Dr. Heitor Vieira Dourado (FMT-HVD); Fundação de Amparo à Pesquisa do Estado do Amazonas (FAPEAM): Universal Amazonas, Programa Pró-Estado, Programa POSGRAD 2020; Ministério da Saúde do Brasil: Programa de Pesquisa para o SUS (PPSUS) e Departamento de Ciência e Tecnologia; Instituto Leônidas & Maria Deane (ILMD/Fiocruz Amazônia) em parceria com o Conselho Nacional de Desenvolvimento Científico e Tecnológico Desenvolvimento (CNPq) e parcialmente financiado pela Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES).
publishDate 2021
dc.date.issued.fl_str_mv 2021
dc.date.accessioned.fl_str_mv 2023-02-06T19:51:00Z
dc.date.available.fl_str_mv 2023-02-06T19:51:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv ANDRADE, Anny Beatriz Costa Antony de et al. Hematological Profile of Pregnant Women with Suspected Zika Virus Infection Followed Up at a Referral Service in Manaus, Brazil. Viruses, Basel, v. 13, n. 4, p. 1-11, 2021.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/56901
dc.identifier.issn.en_US.fl_str_mv 1999-4915
dc.identifier.doi.none.fl_str_mv 10.3390/v13040710
identifier_str_mv ANDRADE, Anny Beatriz Costa Antony de et al. Hematological Profile of Pregnant Women with Suspected Zika Virus Infection Followed Up at a Referral Service in Manaus, Brazil. Viruses, Basel, v. 13, n. 4, p. 1-11, 2021.
1999-4915
10.3390/v13040710
url https://www.arca.fiocruz.br/handle/icict/56901
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
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reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
bitstream.url.fl_str_mv https://www.arca.fiocruz.br/bitstream/icict/56901/1/license.txt
https://www.arca.fiocruz.br/bitstream/icict/56901/2/Andrade_Anny_etal_ILMD_2021.pdf
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