In vivo lymphocyte activation and apoptosis by lectins of the Diocleinae subtribe

Detalhes bibliográficos
Autor(a) principal: Bessa, Theolis Costa Barbosa
Data de Publicação: 2001
Outros Autores: Arruda, Sérgio Marcos, Cavada, Benildo Sousa, Grangeiro, Thalles Barbosa, Freitas, Luiz Antonio Rodrigues de, Barral Netto, Manoel
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/6291
Resumo: Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil
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spelling Bessa, Theolis Costa BarbosaArruda, Sérgio MarcosCavada, Benildo SousaGrangeiro, Thalles BarbosaFreitas, Luiz Antonio Rodrigues deBarral Netto, Manoel2013-02-04T20:49:03Z2013-02-04T20:49:03Z2001BARBOSA, T. et al. In vivo lymphocyte activation and apoptosis by lectins of the Diocleinae subtribe. Memórias do Instituto Oswaldo Cruz, v. 96, n. 5, p. 673-678, july. 2001.0074-0276https://www.arca.fiocruz.br/handle/icict/6291engIn vivo lymphocyte activation and apoptosis by lectins of the Diocleinae subtribeinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, BrasilFundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, BrasilUniversidade Federal do Ceará. Centro de Ciências. Fortaleza, CE, BrasilUniversidade Federal do Ceará. Centro de Ciências. Fortaleza, CE, BrasilFundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, BrasilFundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, BrasilThis paper reports the overall effects of three lectins, extracted from Canavalia brasiliensis, Dioclea violacea, and D. grandiflora, on BALB/c mice popliteal draining lymph nodes. These lectins have presented high stimulatory capacity on lymph node T cells. Additionally, they were able to induce apoptosis and inflammation (frequently associated with high endothelial venule necrosis). The data presented here suggest that the Diocleinae lectins studied can stimulate in vivo T cell activation and apoptosis, as well as present important side effects.AdjuvantsApoptosisDiocleinaeLectinLinfonodos/patologiaSequência de AminoácidosAtivação Linfocitária/efeitos de drogasApoptose/efeitos de drogasLectinas/farmacologiaFabaceae/químicaLinfonodos/efeitos de drogasFabaceae/genéticaInflamação/induzido quimicamenteReceptores de Interleucina-2/metabolismoVênulas/patologiaEndotélio/irrigação sanguíneaNecroseContagem de CélulasCamundongos Endogâmicos BALB CAnimaisCamundongosMasculinoFemininoResearch Support, Non-U.S. Gov'tinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZORIGINALBarbosa, Theolis In vivo lymphocyte,,,.pdfBarbosa, Theolis In vivo lymphocyte,,,.pdfapplication/pdf116908https://www.arca.fiocruz.br/bitstream/icict/6291/1/Barbosa%2c%20Theolis%20In%20vivo%20lymphocyte%2c%2c%2c.pdf2b1dd633cc13ab79e81fa9bef34866aeMD51LICENSElicense.txtlicense.txttext/plain; charset=utf-81914https://www.arca.fiocruz.br/bitstream/icict/6291/2/license.txt7d48279ffeed55da8dfe2f8e81f3b81fMD52TEXTBarbosa, Theolis In vivo lymphocyte,,,.pdf.txtBarbosa, Theolis In vivo lymphocyte,,,.pdf.txtExtracted texttext/plain24829https://www.arca.fiocruz.br/bitstream/icict/6291/5/Barbosa%2c%20Theolis%20In%20vivo%20lymphocyte%2c%2c%2c.pdf.txt7f6d7ff79308f28a0cf4387ed43bdf7cMD55THUMBNAILBarbosa, Theolis In vivo lymphocyte,,,.pdf.jpgBarbosa, Theolis In vivo lymphocyte,,,.pdf.jpgGenerated Thumbnailimage/jpeg2446https://www.arca.fiocruz.br/bitstream/icict/6291/4/Barbosa%2c%20Theolis%20In%20vivo%20lymphocyte%2c%2c%2c.pdf.jpgf8d8401affb9221707ab2902eeea8891MD54icict/62912023-03-15 14:33:12.666oai:www.arca.fiocruz.br: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ório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352023-03-15T17:33:12Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.pt_BR.fl_str_mv In vivo lymphocyte activation and apoptosis by lectins of the Diocleinae subtribe
title In vivo lymphocyte activation and apoptosis by lectins of the Diocleinae subtribe
spellingShingle In vivo lymphocyte activation and apoptosis by lectins of the Diocleinae subtribe
Bessa, Theolis Costa Barbosa
Adjuvants
Apoptosis
Diocleinae
Lectin
Linfonodos/patologia
Sequência de Aminoácidos
Ativação Linfocitária/efeitos de drogas
Apoptose/efeitos de drogas
Lectinas/farmacologia
Fabaceae/química
Linfonodos/efeitos de drogas
Fabaceae/genética
Inflamação/induzido quimicamente
Receptores de Interleucina-2/metabolismo
Vênulas/patologia
Endotélio/irrigação sanguínea
Necrose
Contagem de Células
Camundongos Endogâmicos BALB C
Animais
Camundongos
Masculino
Feminino
Research Support, Non-U.S. Gov't
title_short In vivo lymphocyte activation and apoptosis by lectins of the Diocleinae subtribe
title_full In vivo lymphocyte activation and apoptosis by lectins of the Diocleinae subtribe
title_fullStr In vivo lymphocyte activation and apoptosis by lectins of the Diocleinae subtribe
title_full_unstemmed In vivo lymphocyte activation and apoptosis by lectins of the Diocleinae subtribe
title_sort In vivo lymphocyte activation and apoptosis by lectins of the Diocleinae subtribe
author Bessa, Theolis Costa Barbosa
author_facet Bessa, Theolis Costa Barbosa
Arruda, Sérgio Marcos
Cavada, Benildo Sousa
Grangeiro, Thalles Barbosa
Freitas, Luiz Antonio Rodrigues de
Barral Netto, Manoel
author_role author
author2 Arruda, Sérgio Marcos
Cavada, Benildo Sousa
Grangeiro, Thalles Barbosa
Freitas, Luiz Antonio Rodrigues de
Barral Netto, Manoel
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Bessa, Theolis Costa Barbosa
Arruda, Sérgio Marcos
Cavada, Benildo Sousa
Grangeiro, Thalles Barbosa
Freitas, Luiz Antonio Rodrigues de
Barral Netto, Manoel
dc.subject.en.pt_BR.fl_str_mv Adjuvants
Apoptosis
Diocleinae
Lectin
Linfonodos/patologia
Sequência de Aminoácidos
topic Adjuvants
Apoptosis
Diocleinae
Lectin
Linfonodos/patologia
Sequência de Aminoácidos
Ativação Linfocitária/efeitos de drogas
Apoptose/efeitos de drogas
Lectinas/farmacologia
Fabaceae/química
Linfonodos/efeitos de drogas
Fabaceae/genética
Inflamação/induzido quimicamente
Receptores de Interleucina-2/metabolismo
Vênulas/patologia
Endotélio/irrigação sanguínea
Necrose
Contagem de Células
Camundongos Endogâmicos BALB C
Animais
Camundongos
Masculino
Feminino
Research Support, Non-U.S. Gov't
dc.subject.decs.pt_BR.fl_str_mv Ativação Linfocitária/efeitos de drogas
Apoptose/efeitos de drogas
Lectinas/farmacologia
Fabaceae/química
Linfonodos/efeitos de drogas
Fabaceae/genética
Inflamação/induzido quimicamente
Receptores de Interleucina-2/metabolismo
Vênulas/patologia
Endotélio/irrigação sanguínea
Necrose
Contagem de Células
Camundongos Endogâmicos BALB C
Animais
Camundongos
Masculino
Feminino
Research Support, Non-U.S. Gov't
description Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil
publishDate 2001
dc.date.issued.fl_str_mv 2001
dc.date.accessioned.fl_str_mv 2013-02-04T20:49:03Z
dc.date.available.fl_str_mv 2013-02-04T20:49:03Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv BARBOSA, T. et al. In vivo lymphocyte activation and apoptosis by lectins of the Diocleinae subtribe. Memórias do Instituto Oswaldo Cruz, v. 96, n. 5, p. 673-678, july. 2001.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/6291
dc.identifier.issn.none.fl_str_mv 0074-0276
identifier_str_mv BARBOSA, T. et al. In vivo lymphocyte activation and apoptosis by lectins of the Diocleinae subtribe. Memórias do Instituto Oswaldo Cruz, v. 96, n. 5, p. 673-678, july. 2001.
0074-0276
url https://www.arca.fiocruz.br/handle/icict/6291
dc.language.iso.fl_str_mv eng
language eng
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