Urban transmission of Chagas disease in Cochabamba, Bolivia

Detalhes bibliográficos
Autor(a) principal: Mercado, Nora Medrano
Data de Publicação: 2008
Outros Autores: Fernandez, R. Ugarte, Butrón, V., Uber-Busek, Solange Cristina, Guerra, H. L., Araujo-Jorge, Tania C., Oliveira, Rodrigo Corrêa de
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/6666
Resumo: Universidad Mayor de San Simón. Faculdade de Ciencias y Tecnología. Departamento de Biología. Laboratorio de Chagas e Inmunoparasitologia. Cochabamba, Bolivia.
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spelling Mercado, Nora MedranoFernandez, R. UgarteButrón, V.Uber-Busek, Solange CristinaGuerra, H. L.Araujo-Jorge, Tania C.Oliveira, Rodrigo Corrêa de2013-07-10T15:25:47Z2013-07-10T15:25:47Z2008MERCADO, Nora Medrano et al. Urban transmission of Chagas disease in Cochabamba, Bolivia. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 103, n. 5, p. 423-430, Aug. 2008.0074-0276https://www.arca.fiocruz.br/handle/icict/666610.1590/S0074-02762008000500003.engUrban transmission of Chagas disease in Cochabamba, Boliviainfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleUniversidad Mayor de San Simón. Faculdade de Ciencias y Tecnología. Departamento de Biología. Laboratorio de Chagas e Inmunoparasitologia. Cochabamba, Bolivia.Universidad Mayor de San Simón. Faculdade de Ciencias y Tecnología. Departamento de Biología. Laboratorio de Chagas e Inmunoparasitologia. Cochabamba, Bolivia.Universidad Mayor de San Simón. Faculdade de Ciencias y Tecnología. Departamento de Biología. Laboratorio de Chagas e Inmunoparasitologia. Cochabamba, Bolivia.Universidad Mayor de San Simón. Faculdade de Ciencias y Tecnología. Departamento de Biología. Laboratorio de Chagas e Inmunoparasitologia. Cochabamba, Bolivia.Universidad Mayor de San Simón. Faculdade de Ciencias y Tecnología. Departamento de Biología. Laboratorio de Chagas e Inmunoparasitologia. Cochabamba, Bolivia.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Biologia Celular. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Centro de Pesquisas René Rachou Laboratório Imunologia Celular e Molecular. Belo Horizonte, MG, Brasil.Chagas disease is a major public health problem in Bolivia. In the city of Cochabamba, 58% of the population lives in peripheral urban districts ("popular zones") where the infection prevalence is extremely high. From 1995 to 1999, we studied the demographics of Chagas infections in children from five to 13 years old (n = 2218) from the South zone (SZ) and North zone (NZ) districts, which differ in social, environmental, and agricultural conditions. Information gathered from these districts demonstrates qualitative and quantitative evidence for the active transmission of Trypanosoma cruzi in urban Cochabamba. Seropositivity was high in both zones (25% in SZ and 19% in NZ). We observed a high risk of infection in children from five to nine years old in SZ, but in NZ, a higher risk occurred in children aged 10-13, with odds ratio for infection three times higher in NZ than in SZ. This difference was not due to triatomine density, since more than 1,000 Triatoma infestans were captured in both zones, but was possibly secondary to the vector infection rate (79% in SZ and 37% in NZ). Electrocardiogram abnormalities were found to be prevalent in children and pre-adolescents (SZ = 40%, NZ = 17%), indicating that under continuous exposure to infection and re-infection, a severe form of the disease may develop early in life. This work demonstrates that T. cruzi infection should also be considered an urban health problem and is not restricted to the rural areas and small villages of Bolivia.Chagas DiseaseAcute phaseRisk factorsChildrenBoliviaEKG abnormalitiesinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZORIGINAL101. MEDRANO-MERCADO N, UGARTE-FERNANDEZ R.pdf101. 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dc.title.pt_BR.fl_str_mv Urban transmission of Chagas disease in Cochabamba, Bolivia
title Urban transmission of Chagas disease in Cochabamba, Bolivia
spellingShingle Urban transmission of Chagas disease in Cochabamba, Bolivia
Mercado, Nora Medrano
Chagas Disease
Acute phase
Risk factors
Children
Bolivia
EKG abnormalities
title_short Urban transmission of Chagas disease in Cochabamba, Bolivia
title_full Urban transmission of Chagas disease in Cochabamba, Bolivia
title_fullStr Urban transmission of Chagas disease in Cochabamba, Bolivia
title_full_unstemmed Urban transmission of Chagas disease in Cochabamba, Bolivia
title_sort Urban transmission of Chagas disease in Cochabamba, Bolivia
author Mercado, Nora Medrano
author_facet Mercado, Nora Medrano
Fernandez, R. Ugarte
Butrón, V.
Uber-Busek, Solange Cristina
Guerra, H. L.
Araujo-Jorge, Tania C.
Oliveira, Rodrigo Corrêa de
author_role author
author2 Fernandez, R. Ugarte
Butrón, V.
Uber-Busek, Solange Cristina
Guerra, H. L.
Araujo-Jorge, Tania C.
Oliveira, Rodrigo Corrêa de
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Mercado, Nora Medrano
Fernandez, R. Ugarte
Butrón, V.
Uber-Busek, Solange Cristina
Guerra, H. L.
Araujo-Jorge, Tania C.
Oliveira, Rodrigo Corrêa de
dc.subject.en.pt_BR.fl_str_mv Chagas Disease
Acute phase
Risk factors
Children
Bolivia
EKG abnormalities
topic Chagas Disease
Acute phase
Risk factors
Children
Bolivia
EKG abnormalities
description Universidad Mayor de San Simón. Faculdade de Ciencias y Tecnología. Departamento de Biología. Laboratorio de Chagas e Inmunoparasitologia. Cochabamba, Bolivia.
publishDate 2008
dc.date.issued.fl_str_mv 2008
dc.date.accessioned.fl_str_mv 2013-07-10T15:25:47Z
dc.date.available.fl_str_mv 2013-07-10T15:25:47Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv MERCADO, Nora Medrano et al. Urban transmission of Chagas disease in Cochabamba, Bolivia. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 103, n. 5, p. 423-430, Aug. 2008.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/6666
dc.identifier.issn.none.fl_str_mv 0074-0276
dc.identifier.doi.none.fl_str_mv 10.1590/S0074-02762008000500003.
identifier_str_mv MERCADO, Nora Medrano et al. Urban transmission of Chagas disease in Cochabamba, Bolivia. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 103, n. 5, p. 423-430, Aug. 2008.
0074-0276
10.1590/S0074-02762008000500003.
url https://www.arca.fiocruz.br/handle/icict/6666
dc.language.iso.fl_str_mv eng
language eng
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