Chest computed tomography findings in severe influenza pneumonia occurring in neutropenic cancer patients

Detalhes bibliográficos
Autor(a) principal: Rodrigues, Rosana Souza
Data de Publicação: 2012
Outros Autores: Marchiori, Edson, Bozza, Fernando A., Pitrowsky, Melissa Tassano, Velasco, Eduardo, Soares, Márcio, Salluh, Jorge I. F.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/36478
Resumo: Federal University of Rio de Janeiro. Rio de Janeiro, RJ, Brazil / D’Or Institute for Research and Education. Rio de Janeiro, RJ, Brazil.
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spelling Rodrigues, Rosana SouzaMarchiori, EdsonBozza, Fernando A.Pitrowsky, Melissa TassanoVelasco, EduardoSoares, MárcioSalluh, Jorge I. F.2019-10-16T11:34:47Z2019-10-16T11:34:47Z2012RODRIGUES, Rosana Souza et al. Chest computed tomography findings in severe influenza pneumonia occurring in neutropenic cancer patients. Clinics, v. 67, n. 4, p. 313-318, 2012.1807-5932https://www.arca.fiocruz.br/handle/icict/3647810.6061/clinics/2012(04)031980-5322engFaculdade de Medicina / USPChest computed tomography findings in severe influenza pneumonia occurring in neutropenic cancer patientsinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFederal University of Rio de Janeiro. Rio de Janeiro, RJ, Brazil / D’Or Institute for Research and Education. Rio de Janeiro, RJ, Brazil.Federal University of Rio de Janeiro. Rio de Janeiro, RJ, Brazil.D’Or Institute for Research and Education. Rio de Janeiro, RJ, Brazil / Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Rio de Janeiro, RJ, Brasil.Instituto Nacional de Câncer. Intensive Care Unit and Postgraduate Program. Rio de Janeiro, RJ, Brazil.Instituto Nacional de Câncer. Infectious Diseases Department. Rio de Janeiro, RJ, Brazil.D’Or Institute for Research and Education. Rio de Janeiro, RJ, Brazil / Instituto Nacional de Câncer. Intensive Care Unit and Postgraduate Program. Rio de Janeiro, RJ, Brazil.D’Or Institute for Research and Education. Rio de Janeiro, RJ, Brazil / Instituto Nacional de Câncer. Intensive Care Unit and Postgraduate Program. Rio de Janeiro, RJ, Brazil.OBJECTIVE: To describe the chest computed tomography findings for severe influenza H1N1 infection in a series of hospitalized neutropenic cancer patients. METHODS: We performed a retrospective systematic analysis of chest computed tomography scans for eight hospitalized patients with fever, neutropenia, and confirmed diagnoses of influenza H1N1. The clinical data had been prospectively collected. RESULTS: Six of eight patients (75%) developed respiratory failure and required intensive care. Prolonged H1N1 shedding was observed in the three mechanically ventilated patients, and overall hospital mortality in our series was 25%. The most frequent computed tomography findings were ground-glass opacity (all patients), consolidation (7/8 cases), and airspace nodules (6/8 cases) that were frequently moderate or severe. Other parenchymal findings were not common. Five patients had features of pneumonia, two had computed tomography findings compatible with bronchitis and/or bronchiolitis, and one had tomographic signs of chronicity. CONCLUSION: In this series of neutropenic patients with severe influenza H1N1 infection, chest computed tomography demonstrated mainly moderate or severe parenchymatous disease, but bronchiolitis was not a common feature. These findings associated with febrile neutropenia should elicit a diagnosis of severe viral infection.H1N1Viral pneumoniaNeutropeniaCancerComputed tomographyinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-83104https://www.arca.fiocruz.br/bitstream/icict/36478/1/license.txt79178e5f2a0eb066867a274556814938MD51ORIGINALve_Rodrigues_Rosana_etal_INI_2012.pdfve_Rodrigues_Rosana_etal_INI_2012.pdfapplication/pdf581897https://www.arca.fiocruz.br/bitstream/icict/36478/2/ve_Rodrigues_Rosana_etal_INI_2012.pdfc670373acbf52f39c49466732272d762MD52TEXTve_Rodrigues_Rosana_etal_INI_2012.pdf.txtve_Rodrigues_Rosana_etal_INI_2012.pdf.txtExtracted texttext/plain31008https://www.arca.fiocruz.br/bitstream/icict/36478/3/ve_Rodrigues_Rosana_etal_INI_2012.pdf.txt49b1e7879d3e6bbf76efb87b85244159MD53icict/364782019-10-17 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dc.title.pt_BR.fl_str_mv Chest computed tomography findings in severe influenza pneumonia occurring in neutropenic cancer patients
title Chest computed tomography findings in severe influenza pneumonia occurring in neutropenic cancer patients
spellingShingle Chest computed tomography findings in severe influenza pneumonia occurring in neutropenic cancer patients
Rodrigues, Rosana Souza
H1N1
Viral pneumonia
Neutropenia
Cancer
Computed tomography
title_short Chest computed tomography findings in severe influenza pneumonia occurring in neutropenic cancer patients
title_full Chest computed tomography findings in severe influenza pneumonia occurring in neutropenic cancer patients
title_fullStr Chest computed tomography findings in severe influenza pneumonia occurring in neutropenic cancer patients
title_full_unstemmed Chest computed tomography findings in severe influenza pneumonia occurring in neutropenic cancer patients
title_sort Chest computed tomography findings in severe influenza pneumonia occurring in neutropenic cancer patients
author Rodrigues, Rosana Souza
author_facet Rodrigues, Rosana Souza
Marchiori, Edson
Bozza, Fernando A.
Pitrowsky, Melissa Tassano
Velasco, Eduardo
Soares, Márcio
Salluh, Jorge I. F.
author_role author
author2 Marchiori, Edson
Bozza, Fernando A.
Pitrowsky, Melissa Tassano
Velasco, Eduardo
Soares, Márcio
Salluh, Jorge I. F.
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Rodrigues, Rosana Souza
Marchiori, Edson
Bozza, Fernando A.
Pitrowsky, Melissa Tassano
Velasco, Eduardo
Soares, Márcio
Salluh, Jorge I. F.
dc.subject.en.pt_BR.fl_str_mv H1N1
Viral pneumonia
Neutropenia
Cancer
Computed tomography
topic H1N1
Viral pneumonia
Neutropenia
Cancer
Computed tomography
description Federal University of Rio de Janeiro. Rio de Janeiro, RJ, Brazil / D’Or Institute for Research and Education. Rio de Janeiro, RJ, Brazil.
publishDate 2012
dc.date.issued.fl_str_mv 2012
dc.date.accessioned.fl_str_mv 2019-10-16T11:34:47Z
dc.date.available.fl_str_mv 2019-10-16T11:34:47Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv RODRIGUES, Rosana Souza et al. Chest computed tomography findings in severe influenza pneumonia occurring in neutropenic cancer patients. Clinics, v. 67, n. 4, p. 313-318, 2012.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/36478
dc.identifier.issn.pt_BR.fl_str_mv 1807-5932
dc.identifier.doi.none.fl_str_mv 10.6061/clinics/2012(04)03
dc.identifier.eissn.none.fl_str_mv 1980-5322
identifier_str_mv RODRIGUES, Rosana Souza et al. Chest computed tomography findings in severe influenza pneumonia occurring in neutropenic cancer patients. Clinics, v. 67, n. 4, p. 313-318, 2012.
1807-5932
10.6061/clinics/2012(04)03
1980-5322
url https://www.arca.fiocruz.br/handle/icict/36478
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Faculdade de Medicina / USP
publisher.none.fl_str_mv Faculdade de Medicina / USP
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
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