Immunophenotypic aspects of cylindroma and nodular hidradenoma

Detalhes bibliográficos
Autor(a) principal: Canedo, T.
Data de Publicação: 2010
Outros Autores: Almeida, M. P. de, Cuzzi, T., Ramos-e-Silva, M.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/37706
Resumo: Tullia Cuzzi. Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Documento produzido em parceria ou por autor vinculado à Fiocruz, mas não consta a informação no documento.
id CRUZ_44e6e28778658537cd2a8af94187d1ca
oai_identifier_str oai:www.arca.fiocruz.br:icict/37706
network_acronym_str CRUZ
network_name_str Repositório Institucional da FIOCRUZ (ARCA)
repository_id_str 2135
spelling Canedo, T.Almeida, M. P. deCuzzi, T.Ramos-e-Silva, M.2019-12-09T13:35:32Z2019-12-09T13:35:32Z2010CANEDO, T. et al. Immunophenotypic aspects of cylindroma and nodular hidradenoma. Journal of the European Academy of Dermatology and Venereology, v. 24, p. 178-185, 2010.0926-9959https://www.arca.fiocruz.br/handle/icict/3770610.1111/j.1468-3083.2009.03398.x1468-3083Tullia Cuzzi. Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Documento produzido em parceria ou por autor vinculado à Fiocruz, mas não consta a informação no documento.2020-12-09Federal University of Rio de Janeiro. School of Medicine. Rio de Janeiro, RJ, Brazil / Federal University of Rio de Janeiro. University Hospital. Rio de Janeiro, RJ, Brazil.Federal University of Rio de Janeiro. Biomedical Sciences Institute. Sector of Dermatology. Rio de Janeiro, RJ, Brazil.Federal University of Rio de Janeiro. School of Medicine. Rio de Janeiro, RJ, Brazil / Federal University of Rio de Janeiro. University Hospital. Rio de Janeiro, RJ, Brazil.Federal University of Rio de Janeiro. School of Medicine. Rio de Janeiro, RJ, Brazil / Federal University of Rio de Janeiro. University Hospital. Rio de Janeiro, RJ, Brazil.Background: Some adnexal tumours have many controversies about their histogenesis. Objectives: To evaluate the eccrine and/or apocrine differentiation phenotype in cases of cylindroma and clear cell hidradenoma with CD15 and p63 antibodies. Methodology: Slides and blocks of six cases of cylindroma and seven cases of nodular hidradenoma (clear cells) were analyzed by the technique of immunohistochemistry with CD15 and p63 antibodies. Results: In all cases of cylindroma we obtained negative results for CD15 antibody and positive for p63 antibody. In five of seven cases of nodular hidradenoma (clear cell), we could easily observe clear cells between 20% and 50% of tumour cells. In the two other cases, cystic lesions were present and occasional clear cells could be seen. The reaction with CD15 antibody was positive in granular and cytoplasmic pattern in six of seven cases, especially in cells with suggestive clear cytoplasm in lower proportion than this clear cells could be seen in haematoxylin and eosin. The positivity for p63 antibody, nuclear pattern, was observed in six of seven cases, in the major part of tumour cells. In only one case, the positivity was in 20% of cells. Limitation Samples are in small number because these are relatively rare tumours. Conclusions: The present study suggests eccrine origin for both tumours: cylindroma and clear cell hidradenoma.engWileyImmunophenotypic aspects of cylindroma and nodular hidradenomainfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleAdenoid cysticAdenomaCarcinomaCylindromaHidradenomaImmunohistochemistryNeoplasmsSweat glandsinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txttext/plain1748https://www.arca.fiocruz.br/bitstream/icict/37706/1/license.txt8a4605be74aa9ea9d79846c1fba20a33MD51ORIGINALve_Canedo_T_etal_INI_2010.pdfve_Canedo_T_etal_INI_2010.pdfapplication/pdf859694https://www.arca.fiocruz.br/bitstream/icict/37706/2/ve_Canedo_T_etal_INI_2010.pdf1123f0e836a3a6a1279fcd9b6a5ca2c4MD52TEXTve_Canedo_T_etal_INI_2010.pdf.txtve_Canedo_T_etal_INI_2010.pdf.txtExtracted texttext/plain28475https://www.arca.fiocruz.br/bitstream/icict/37706/3/ve_Canedo_T_etal_INI_2010.pdf.txt80c916493cb9dcce4c3479cc4f98c2feMD53icict/377062021-03-24 16:32:40.441oai:www.arca.fiocruz.br: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Repositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352021-03-24T19:32:40Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.pt_BR.fl_str_mv Immunophenotypic aspects of cylindroma and nodular hidradenoma
title Immunophenotypic aspects of cylindroma and nodular hidradenoma
spellingShingle Immunophenotypic aspects of cylindroma and nodular hidradenoma
Canedo, T.
Adenoid cystic
Adenoma
Carcinoma
Cylindroma
Hidradenoma
Immunohistochemistry
Neoplasms
Sweat glands
title_short Immunophenotypic aspects of cylindroma and nodular hidradenoma
title_full Immunophenotypic aspects of cylindroma and nodular hidradenoma
title_fullStr Immunophenotypic aspects of cylindroma and nodular hidradenoma
title_full_unstemmed Immunophenotypic aspects of cylindroma and nodular hidradenoma
title_sort Immunophenotypic aspects of cylindroma and nodular hidradenoma
author Canedo, T.
author_facet Canedo, T.
Almeida, M. P. de
Cuzzi, T.
Ramos-e-Silva, M.
author_role author
author2 Almeida, M. P. de
Cuzzi, T.
Ramos-e-Silva, M.
author2_role author
author
author
dc.contributor.author.fl_str_mv Canedo, T.
Almeida, M. P. de
Cuzzi, T.
Ramos-e-Silva, M.
dc.subject.en.pt_BR.fl_str_mv Adenoid cystic
Adenoma
Carcinoma
Cylindroma
Hidradenoma
Immunohistochemistry
Neoplasms
Sweat glands
topic Adenoid cystic
Adenoma
Carcinoma
Cylindroma
Hidradenoma
Immunohistochemistry
Neoplasms
Sweat glands
description Tullia Cuzzi. Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Documento produzido em parceria ou por autor vinculado à Fiocruz, mas não consta a informação no documento.
publishDate 2010
dc.date.issued.fl_str_mv 2010
dc.date.accessioned.fl_str_mv 2019-12-09T13:35:32Z
dc.date.available.fl_str_mv 2019-12-09T13:35:32Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv CANEDO, T. et al. Immunophenotypic aspects of cylindroma and nodular hidradenoma. Journal of the European Academy of Dermatology and Venereology, v. 24, p. 178-185, 2010.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/37706
dc.identifier.issn.pt_BR.fl_str_mv 0926-9959
dc.identifier.doi.none.fl_str_mv 10.1111/j.1468-3083.2009.03398.x
dc.identifier.eissn.none.fl_str_mv 1468-3083
identifier_str_mv CANEDO, T. et al. Immunophenotypic aspects of cylindroma and nodular hidradenoma. Journal of the European Academy of Dermatology and Venereology, v. 24, p. 178-185, 2010.
0926-9959
10.1111/j.1468-3083.2009.03398.x
1468-3083
url https://www.arca.fiocruz.br/handle/icict/37706
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Wiley
publisher.none.fl_str_mv Wiley
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
bitstream.url.fl_str_mv https://www.arca.fiocruz.br/bitstream/icict/37706/1/license.txt
https://www.arca.fiocruz.br/bitstream/icict/37706/2/ve_Canedo_T_etal_INI_2010.pdf
https://www.arca.fiocruz.br/bitstream/icict/37706/3/ve_Canedo_T_etal_INI_2010.pdf.txt
bitstream.checksum.fl_str_mv 8a4605be74aa9ea9d79846c1fba20a33
1123f0e836a3a6a1279fcd9b6a5ca2c4
80c916493cb9dcce4c3479cc4f98c2fe
bitstream.checksumAlgorithm.fl_str_mv MD5
MD5
MD5
repository.name.fl_str_mv Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)
repository.mail.fl_str_mv repositorio.arca@fiocruz.br
_version_ 1798325044006354944