Moving towards a strategy to accelerate cervical cancer elimination in a high-burden city: lessons learned from the Amazon city of Manaus, Brazil
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2021 |
| Outros Autores: | , , , , , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
| Texto Completo: | https://www.arca.fiocruz.br/handle/icict/54462 |
Resumo: | Amazon State Oncology Control Foundation. Manaus, AM, Brazil / The Federal University of Amazonas. Post Graduation Program in Health Sciences and Basic and Applied Immunology. Manaus, AM, Brazil / Fundação Oswaldo Cruz. Fiocruz Brasília. Núcleo de Epidemiologia e Vigilância em Saúde. Brasília, DF, Brasil. |
| id |
CRUZ_4505ab3c42c9679962d7507e62dcb7c8 |
|---|---|
| oai_identifier_str |
oai:www.arca.fiocruz.br:icict/54462 |
| network_acronym_str |
CRUZ |
| network_name_str |
Repositório Institucional da FIOCRUZ (ARCA) |
| repository_id_str |
2135 |
| spelling |
Torres, Kátia LuzRondon, Heidy Halanna de Melo FarahMartins, Toni RicardoMartins, SandroSaturnino, Ana Conceição Ribeiro DantasRaiol, TaináMarques, Carla PintasCorrêa, FlaviaMigowski, ArnMinuzzi-Souza, Thais Tâmara Castro eSchiffman, MarkRodriguez, Ana CeciliaGage, Julia C.2022-08-05T02:01:08Z2022-08-05T02:01:08Z2021TORRES, Katia Luz et al. Moving towards a strategy to accelerate cervical cancer elimination in a high-burden city: lessons learned from the Amazon city of Manaus, Brazil. Plos One, [San Francisco], v. 16, n. 10, e0258539, p. 1-15, 2021.1932-6203https://www.arca.fiocruz.br/handle/icict/5446210.1371/journal.pone.0258539engPublic Library of SciencePapillomavirus VaccinesUterine Cervical NeoplasmsCervical cancerHPV vaccineManaus, BrazilNeoplasias do Colo do ÚteroVacinas contra PapillomavirusMoving towards a strategy to accelerate cervical cancer elimination in a high-burden city: lessons learned from the Amazon city of Manaus, Brazilinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleAmazon State Oncology Control Foundation. Manaus, AM, Brazil / The Federal University of Amazonas. Post Graduation Program in Health Sciences and Basic and Applied Immunology. Manaus, AM, Brazil / Fundação Oswaldo Cruz. Fiocruz Brasília. Núcleo de Epidemiologia e Vigilância em Saúde. Brasília, DF, Brasil.The Federal University of Amazonas. Post Graduation Program in Health Sciences and Basic and Applied Immunology. Manaus, AM, Brazil / Fundação Oswaldo Cruz. Fiocruz Brasília. Núcleo de Epidemiologia e Vigilância em Saúde. Brasília, DF, Brasil.São Paulo University. Tropical Medicine Institute. Virology Laboratory. São Paulo, SP, Brazil.Fundação Oswaldo Cruz. Fiocruz Brasília. Núcleo de Epidemiologia e Vigilância em Saúde. Brasília, DF, Brazil.Fundação Oswaldo Cruz. Fiocruz Brasília. Núcleo de Epidemiologia e Vigilância em Saúde. Brasília, DF, Brasil / University of Brasília. Faculty of Health Sciences. Department of Pharmacy. Brasília, DF, Brazil.Fundação Oswaldo Cruz. Fiocruz Brasília. Núcleo de Epidemiologia e Vigilância em Saúde. Brasília, DF, Brasil.Fundação Oswaldo Cruz. Fiocruz Brasília. Núcleo de Epidemiologia e Vigilância em Saúde. Brasília, DF, Brasil / University of Brasília. Collective Health. Brasília, DF, Brazil.Brazilian National Cancer Institute. Cancer Early Detection Division. Rio de Janeiro, RJ, Brazil.Brazilian National Cancer Institute. Cancer Early Detection Division. Rio de Janeiro, RJ, Brazil.Fundação Oswaldo Cruz. Fiocruz Brasília. Núcleo de Epidemiologia e Vigilância em Saúde. Brasília, DF, Brasil / Ministry of Health. Health Surveillance Secretariat. National Immunization Program. Brasília, DF, Brazil.National Cancer Institute. Division of Cancer Epidemiology and Genetics. Bethesda, MD, United States of America.The World Health Organization Call to Eliminate Cervical Cancer resonates in cities like Manaus, Brazil, where the burden is among the world’s highest. Manaus has offered free cytology-based screening since 1990 and HPV immunization since 2013, but the public system is constrained by many challenges and performance is not well-defined. We obtained cervical cancer prevention activities within Manaus public health records for 2019 to evaluate immunization and screening coverage, screening by region and neighborhood, and the annual Pink October screening campaign. We estimated that among girls and boys age 14–18, 85.9% and 64.9% had 1+ doses of HPV vaccine, higher than rates for age 9–13 (73.4% and 43.3%, respectively). Of the 90,209 cytology tests performed, 24.9% were outside the target age and the remaining 72,230 corresponded to 40.1% of the target population (one-third of women age 25–64). The East zone had highest screening coverage (49.1%), highest high-grade cytology rate (2.5%) and lowest estimated cancers (38.1/100,000) compared with the South zone (32.9%, 1.8% and 48.5/100,000, respectively). Largest neighborhoods had fewer per capita screening locations, resulting in lower coverage. During October, some clinics successfully achieved higher screening volumes and high-grade cytology rates (up to 15.4%). Although we found evidence of some follow-up within 10 months post-screening for 51/70 women (72.9%) with high-grade or worse cytology, only 18 had complete work-up confirmed. Manaus has successfully initiated HPV vaccination, forecasting substantial cervical cancer reductions by 2050. With concerted efforts during campaigns, some clinics improved screening coverage and reached high-risk women. Screening campaigns in community locations in high-risk neighborhoods using self-collected HPV testing can achieve widespread coverage. Simplifying triage and treatment with fewer visits closer to communities would greatly improve follow-up and program effectiveness. Achieving WHO Cervical Cancer Elimination goals in high-burden cities will require major reforms for screening and simpler follow-up and treatment.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-83074https://www.arca.fiocruz.br/bitstream/icict/54462/1/license.txtd3e717dbb24bfc607ede047f44d29a0eMD51ORIGINALve_Katia_Torres_etal_Fiocruz_BSB_2021.pdfve_Katia_Torres_etal_Fiocruz_BSB_2021.pdfapplication/pdf1035672https://www.arca.fiocruz.br/bitstream/icict/54462/2/ve_Katia_Torres_etal_Fiocruz_BSB_2021.pdf9d03770b41f59b2281c2c4b0bdb5e60eMD52icict/544622022-08-04 23:01:08.891oai:www.arca.fiocruz.br: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Repositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352022-08-05T02:01:08Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false |
| dc.title.pt_BR.fl_str_mv |
Moving towards a strategy to accelerate cervical cancer elimination in a high-burden city: lessons learned from the Amazon city of Manaus, Brazil |
| title |
Moving towards a strategy to accelerate cervical cancer elimination in a high-burden city: lessons learned from the Amazon city of Manaus, Brazil |
| spellingShingle |
Moving towards a strategy to accelerate cervical cancer elimination in a high-burden city: lessons learned from the Amazon city of Manaus, Brazil Torres, Kátia Luz Papillomavirus Vaccines Uterine Cervical Neoplasms Cervical cancer HPV vaccine Manaus, Brazil Neoplasias do Colo do Útero Vacinas contra Papillomavirus |
| title_short |
Moving towards a strategy to accelerate cervical cancer elimination in a high-burden city: lessons learned from the Amazon city of Manaus, Brazil |
| title_full |
Moving towards a strategy to accelerate cervical cancer elimination in a high-burden city: lessons learned from the Amazon city of Manaus, Brazil |
| title_fullStr |
Moving towards a strategy to accelerate cervical cancer elimination in a high-burden city: lessons learned from the Amazon city of Manaus, Brazil |
| title_full_unstemmed |
Moving towards a strategy to accelerate cervical cancer elimination in a high-burden city: lessons learned from the Amazon city of Manaus, Brazil |
| title_sort |
Moving towards a strategy to accelerate cervical cancer elimination in a high-burden city: lessons learned from the Amazon city of Manaus, Brazil |
| author |
Torres, Kátia Luz |
| author_facet |
Torres, Kátia Luz Rondon, Heidy Halanna de Melo Farah Martins, Toni Ricardo Martins, Sandro Saturnino, Ana Conceição Ribeiro Dantas Raiol, Tainá Marques, Carla Pintas Corrêa, Flavia Migowski, Arn Minuzzi-Souza, Thais Tâmara Castro e Schiffman, Mark Rodriguez, Ana Cecilia Gage, Julia C. |
| author_role |
author |
| author2 |
Rondon, Heidy Halanna de Melo Farah Martins, Toni Ricardo Martins, Sandro Saturnino, Ana Conceição Ribeiro Dantas Raiol, Tainá Marques, Carla Pintas Corrêa, Flavia Migowski, Arn Minuzzi-Souza, Thais Tâmara Castro e Schiffman, Mark Rodriguez, Ana Cecilia Gage, Julia C. |
| author2_role |
author author author author author author author author author author author author |
| dc.contributor.author.fl_str_mv |
Torres, Kátia Luz Rondon, Heidy Halanna de Melo Farah Martins, Toni Ricardo Martins, Sandro Saturnino, Ana Conceição Ribeiro Dantas Raiol, Tainá Marques, Carla Pintas Corrêa, Flavia Migowski, Arn Minuzzi-Souza, Thais Tâmara Castro e Schiffman, Mark Rodriguez, Ana Cecilia Gage, Julia C. |
| dc.subject.mesh.pt_BR.fl_str_mv |
Papillomavirus Vaccines Uterine Cervical Neoplasms |
| topic |
Papillomavirus Vaccines Uterine Cervical Neoplasms Cervical cancer HPV vaccine Manaus, Brazil Neoplasias do Colo do Útero Vacinas contra Papillomavirus |
| dc.subject.en.pt_BR.fl_str_mv |
Cervical cancer HPV vaccine Manaus, Brazil |
| dc.subject.decs.pt_BR.fl_str_mv |
Neoplasias do Colo do Útero Vacinas contra Papillomavirus |
| description |
Amazon State Oncology Control Foundation. Manaus, AM, Brazil / The Federal University of Amazonas. Post Graduation Program in Health Sciences and Basic and Applied Immunology. Manaus, AM, Brazil / Fundação Oswaldo Cruz. Fiocruz Brasília. Núcleo de Epidemiologia e Vigilância em Saúde. Brasília, DF, Brasil. |
| publishDate |
2021 |
| dc.date.issued.fl_str_mv |
2021 |
| dc.date.accessioned.fl_str_mv |
2022-08-05T02:01:08Z |
| dc.date.available.fl_str_mv |
2022-08-05T02:01:08Z |
| dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
| dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
| format |
article |
| status_str |
publishedVersion |
| dc.identifier.citation.fl_str_mv |
TORRES, Katia Luz et al. Moving towards a strategy to accelerate cervical cancer elimination in a high-burden city: lessons learned from the Amazon city of Manaus, Brazil. Plos One, [San Francisco], v. 16, n. 10, e0258539, p. 1-15, 2021. |
| dc.identifier.uri.fl_str_mv |
https://www.arca.fiocruz.br/handle/icict/54462 |
| dc.identifier.issn.pt_BR.fl_str_mv |
1932-6203 |
| dc.identifier.doi.none.fl_str_mv |
10.1371/journal.pone.0258539 |
| identifier_str_mv |
TORRES, Katia Luz et al. Moving towards a strategy to accelerate cervical cancer elimination in a high-burden city: lessons learned from the Amazon city of Manaus, Brazil. Plos One, [San Francisco], v. 16, n. 10, e0258539, p. 1-15, 2021. 1932-6203 10.1371/journal.pone.0258539 |
| url |
https://www.arca.fiocruz.br/handle/icict/54462 |
| dc.language.iso.fl_str_mv |
eng |
| language |
eng |
| dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
| eu_rights_str_mv |
openAccess |
| dc.publisher.none.fl_str_mv |
Public Library of Science |
| publisher.none.fl_str_mv |
Public Library of Science |
| dc.source.none.fl_str_mv |
reponame:Repositório Institucional da FIOCRUZ (ARCA) instname:Fundação Oswaldo Cruz (FIOCRUZ) instacron:FIOCRUZ |
| instname_str |
Fundação Oswaldo Cruz (FIOCRUZ) |
| instacron_str |
FIOCRUZ |
| institution |
FIOCRUZ |
| reponame_str |
Repositório Institucional da FIOCRUZ (ARCA) |
| collection |
Repositório Institucional da FIOCRUZ (ARCA) |
| bitstream.url.fl_str_mv |
https://www.arca.fiocruz.br/bitstream/icict/54462/1/license.txt https://www.arca.fiocruz.br/bitstream/icict/54462/2/ve_Katia_Torres_etal_Fiocruz_BSB_2021.pdf |
| bitstream.checksum.fl_str_mv |
d3e717dbb24bfc607ede047f44d29a0e 9d03770b41f59b2281c2c4b0bdb5e60e |
| bitstream.checksumAlgorithm.fl_str_mv |
MD5 MD5 |
| repository.name.fl_str_mv |
Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ) |
| repository.mail.fl_str_mv |
repositorio.arca@fiocruz.br |
| _version_ |
1798324673550745600 |