Genetic and biological characterization of a densovirus isolate that affects dengue virus infection

Bibliographic Details
Main Author: Mosimann, Ana Luiza Pamplona
Publication Date: 2011
Other Authors: Bordignon, Juliano, Mazzarotto, Giovanny Augusto Camacho Antevere, Motta, Maria Cristina Machado, Hoffmann, Federico, Santos, Claudia Nunes Duarte dos
Format: Article
Language: por
Source: Repositório Institucional da FIOCRUZ (ARCA)
Download full: https://www.arca.fiocruz.br/handle/icict/39822
Summary: Fundação Oswaldo Cruz. Instituto Carlos Chagas. Curitiba, PR, Brasil.
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spelling Mosimann, Ana Luiza PamplonaBordignon, JulianoMazzarotto, Giovanny Augusto Camacho AntevereMotta, Maria Cristina MachadoHoffmann, FedericoSantos, Claudia Nunes Duarte dos2020-02-10T20:03:33Z2020-02-10T20:03:33Z2011MOSIMANN, Ana Luiza Pamplona et al. Genetic and biological characterization of a densovirus isolate that affects dengue virus infection. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 106, n. 3, p. 285-292, 2011.1678-8060https://www.arca.fiocruz.br/handle/icict/3982210.1590/s0074-027620110003000061678-8060porFundação Oswaldo Cruz. Instituto Oswaldo CruzGenetic and biological characterization of a densovirus isolate that affects dengue virus infectioninfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Carlos Chagas. Curitiba, PR, Brasil.Fundação Oswaldo Cruz. Instituto Carlos Chagas. Curitiba, PR, Brasil.Fundação Oswaldo Cruz. Instituto Carlos Chagas. Curitiba, PR, Brasil.Universidade Federal do Rio de Janeiro. Instituto de Biofísica Carlos Chagas Filho. Rio de Janeiro, RJ, Brasil.Department of Biochemistry and Molecular Biology. Mississippi State University. Mississippi State, USA.Fundação Oswaldo Cruz. Instituto Carlos Chagas. Curitiba, PR, Brasil.Brevidensoviruses have an encapsidated, single-stranded DNA genome that predominantly has a negative polarity. In recent years, they have received particular attention due to their potential role in the biological control of pathogenic arboviruses and to their unnoticed presence in cell cultures as contaminants. In addition, brevidensoviruses may also be useful as viral vectors. This study describes the first genetic and biological characterization of a mosquito densovirus that was isolated in Brazil; moreover, we examined the phylogenetic relationship between this isolate and the other brevidensoviruses. We further demonstrate that this densovirus has the potential to be used to biologically control dengue virus (DENV) infection with in vitro co-infection experiments. The present study provides evidence that this densovirus isolate is a fast-spreading virus that affects cell growth and DENV infection.Biological controlDengue VirusVirus del DengueDensovirusDensovirinaeVírus da Dengueinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-83084https://www.arca.fiocruz.br/bitstream/icict/39822/1/license.txt783568c2893d2e25a99990b126be1772MD51ORIGINAL06ok.pdf06ok.pdfapplication/pdf2585686https://www.arca.fiocruz.br/bitstream/icict/39822/2/06ok.pdff36929f37bf0d04061372786a994e880MD52TEXT06ok.pdf.txt06ok.pdf.txtExtracted texttext/plain46229https://www.arca.fiocruz.br/bitstream/icict/39822/3/06ok.pdf.txt0c58c9b9a01a1b12e51f39148db049d6MD53icict/398222022-01-10 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dc.title.pt_BR.fl_str_mv Genetic and biological characterization of a densovirus isolate that affects dengue virus infection
title Genetic and biological characterization of a densovirus isolate that affects dengue virus infection
spellingShingle Genetic and biological characterization of a densovirus isolate that affects dengue virus infection
Mosimann, Ana Luiza Pamplona
Biological control
Dengue Virus
Virus del Dengue
Densovirus
Densovirinae
Vírus da Dengue
title_short Genetic and biological characterization of a densovirus isolate that affects dengue virus infection
title_full Genetic and biological characterization of a densovirus isolate that affects dengue virus infection
title_fullStr Genetic and biological characterization of a densovirus isolate that affects dengue virus infection
title_full_unstemmed Genetic and biological characterization of a densovirus isolate that affects dengue virus infection
title_sort Genetic and biological characterization of a densovirus isolate that affects dengue virus infection
author Mosimann, Ana Luiza Pamplona
author_facet Mosimann, Ana Luiza Pamplona
Bordignon, Juliano
Mazzarotto, Giovanny Augusto Camacho Antevere
Motta, Maria Cristina Machado
Hoffmann, Federico
Santos, Claudia Nunes Duarte dos
author_role author
author2 Bordignon, Juliano
Mazzarotto, Giovanny Augusto Camacho Antevere
Motta, Maria Cristina Machado
Hoffmann, Federico
Santos, Claudia Nunes Duarte dos
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Mosimann, Ana Luiza Pamplona
Bordignon, Juliano
Mazzarotto, Giovanny Augusto Camacho Antevere
Motta, Maria Cristina Machado
Hoffmann, Federico
Santos, Claudia Nunes Duarte dos
dc.subject.en.pt_BR.fl_str_mv Biological control
Dengue Virus
topic Biological control
Dengue Virus
Virus del Dengue
Densovirus
Densovirinae
Vírus da Dengue
dc.subject.es.pt_BR.fl_str_mv Virus del Dengue
dc.subject.decs.pt_BR.fl_str_mv Densovirus
Densovirinae
Vírus da Dengue
description Fundação Oswaldo Cruz. Instituto Carlos Chagas. Curitiba, PR, Brasil.
publishDate 2011
dc.date.issued.fl_str_mv 2011
dc.date.accessioned.fl_str_mv 2020-02-10T20:03:33Z
dc.date.available.fl_str_mv 2020-02-10T20:03:33Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv MOSIMANN, Ana Luiza Pamplona et al. Genetic and biological characterization of a densovirus isolate that affects dengue virus infection. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 106, n. 3, p. 285-292, 2011.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/39822
dc.identifier.issn.pt_BR.fl_str_mv 1678-8060
dc.identifier.doi.none.fl_str_mv 10.1590/s0074-02762011000300006
dc.identifier.eissn.none.fl_str_mv 1678-8060
identifier_str_mv MOSIMANN, Ana Luiza Pamplona et al. Genetic and biological characterization of a densovirus isolate that affects dengue virus infection. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 106, n. 3, p. 285-292, 2011.
1678-8060
10.1590/s0074-02762011000300006
url https://www.arca.fiocruz.br/handle/icict/39822
dc.language.iso.fl_str_mv por
language por
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Fundação Oswaldo Cruz. Instituto Oswaldo Cruz
publisher.none.fl_str_mv Fundação Oswaldo Cruz. Instituto Oswaldo Cruz
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
bitstream.url.fl_str_mv https://www.arca.fiocruz.br/bitstream/icict/39822/1/license.txt
https://www.arca.fiocruz.br/bitstream/icict/39822/2/06ok.pdf
https://www.arca.fiocruz.br/bitstream/icict/39822/3/06ok.pdf.txt
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repository.name.fl_str_mv Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)
repository.mail.fl_str_mv repositorio.arca@fiocruz.br
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