Fetal demise and failed antibody therapy during Zika virus infection of pregnant macaques

• Autor(a) principal: Bonaldo, Myrna C
• Data de Publicação: 2018
• Outros Autores: Múltipla autoria
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
• Texto Completo: https://www.arca.fiocruz.br/handle/icict/29097
• topic: Zika virus; Infecção; macacas grávidas; falecimento fetal; terapia com anticorpos; falhas; Zika virus; infection; failed antibody therapy; pregnant macaques; Fetal demise

Authors - Diogo M. Magnani 1, Thomas F. Rogers2, Nicholas J. Maness3, Nathan D. Grubaugh2, Nathan Beutler2, Varian K. Bailey1, Lucas Gonzalez-Nieto1, Martin J. Gutman1, Núria Pedreño-Lopez1, Jaclyn M. Kwal1, Michael J. Ricciardi1, Tereance A. Myers3, Justin G. Julander4, Rudolf P. Bohm3, Margaret H. Gilbert3, Faith Schiro3, Pyone P. Aye 3, Robert V. Blair3, Mauricio A. Martins1, Kathrine P. Falkenstein3, Amitinder Kaur3, Christine L. Curry5, Esper G. Kallas6, Ronald C. Desrosiers1, Pascal J. Goldschmidt-Clermont7, Stephen S. Whitehead8, Kristian G. Andersen2,9,10, Myrna C. Bonaldo11, Andrew A. Lackner3, Antonito T. Panganiban3, Dennis R. Burton2,12 & David I. Watkins1 - AFFILIATIONS - 1 Department of Pathology, University of Miami Leonard M. Miller School of Medicine, 1951 NW 7th Ave Room 2340, Miami, FL 33136, USA. 2 Department of Immunology and Microbiology, The Scripps Research Institute, 3215 Merryfield Row Immunology 308, San Diego, CA 92121, USA. 3 Tulane National Primate Research Center, 18703 Three Rivers Road, Covington, LA 70433, USA. 4 Institute for Antiviral Research, Utah State University, 5600 Old Main Hill, Logan, UT 84322-5600, USA. 5 Department of Obstetrics and Gynecology, University of Miami Leonard M. Miller School of Medicine, CRB 11th floor, Miami, FL 33136, USA. 6 Division of Clinical Immunology and Allergy, School of Medicine, University of São Paulo, Av. Dr. Arnaldo 455, Terceiro andar, São Paulo, SP 01246-903, Brazil. 7 Department of Medicine, University of Miami Leonard M. Miller School of Medicine, 1600 NW 10th Ave #1140, Miami, FL, USA. 8 Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bldg 33, Room 3W10A, 33 North Drive, MSC 3210, Bethesda, MD 20892-3210, USA. 9 Scripps Translational Science Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA. 10 Department of Integrative Structural and Computational Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, 92037 La Jolla, CA, USA. 11 Laboratório de Biologia Molecular de Flavivírus, Instituto Oswaldo Cruz, Fiocruz, Avenida Brasil, 4365, Manguinhos, Rio de Janeiro, RJ 21040-360, Brazil. 12 Ragon Institute, Harvard Medical School, 400 Technology Square, Cambridge, Boston, MA 02139, USA. These authors contributed equally: Diogo M. Magnani, Thomas F. Rogers. Deceased: Andrew A. Lackner. Correspondence and requests for materials should be addressed to D.R.B. (email: [e-mail]) or to D.I.W. (email: [e-mail]).