Nutritional profile of newborns with microcephaly and factors associated with worse outcomes
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2019 |
| Outros Autores: | , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
| Texto Completo: | https://www.arca.fiocruz.br/handle/icict/45526 |
Resumo: | Fundação Oswaldo Cruz. Instituto Nacional de Saúde da Mulher, da Criança e do Adolescente Fernandes Figueira. Rio de Janeiro, RJ, Brasil |
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Santos, Samira Fernandes Morais dosSoares, Fernanda Valente MendesAbranches, Andrea Dunshee deCosta, Ana Carolina Carioca daGomes Junior, Saint Clair dos SantosFonseca, Vania de MatosMoreira, Maria Elisabeth Lopes2021-01-07T14:41:18Z2021-01-07T14:41:18Z2019Dos Santos SFM, Soares FVM, de Abranches AD, da Costa ACC, Gomes-Júnior SCDS, Fonseca VM, Moreira MEL. Nutritional profile of newborns with microcephaly and factors associated with worse outcomes. Clinics (Sao Paulo). 2019 Oct 21;74:e798. doi: 10.6061/clinics/2019/e798. PMID: 31644665; PMCID: PMC6791297.1807-5932https://www.arca.fiocruz.br/handle/icict/4552610.6061/clinics/2019/e798engFaculdade de Medicina - USPAdolescentAdultFemaleHumansInfant, NewbornLongitudinal StudiesMaleMicrocephaly / physiopathologyMicrocephaly / virologyNutritional Status / physiologyRisk FactorsSeverity of Illness IndexSocioeconomic FactorsYoung AdultZika Virus Infection / complicationsZika VirusMicrocephalyNutritional StatusNewbornNutritional profile of newborns with microcephaly and factors associated with worse outcomesinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Nacional de Saúde da Mulher, da Criança e do Adolescente Fernandes Figueira. Rio de Janeiro, RJ, BrasilObjective: To describe the nutritional profile of newborns with microcephaly and factors associated with worse outcomes during the first 14 days of life. Methods: This investigation is a longitudinal, descriptive study carried out in 21 full-term neonates exposed vertically to the Zika virus and hospitalized in a neonatal intensive care unit from February to September 2016. Patients receiving parenteral nutrition were excluded. Data analysis was performed using a generalized estimating equation model and Student's t-test to evaluate the association between worsening weight-for-age z-scores and independent clinical, sociodemographic and nutritional variables during hospitalization, with p<0.05 indicating significance. Results: During hospitalization, there was a decrease in the mean values of the weight-for-age z-scores. The factors associated with worse nutritional outcomes were symptomatic exposure to the Zika virus, low maternal schooling, absence of maternal income and consumption of infant formula (p<0.05). Calcification and severe microcephaly were also associated with poor nutritional outcomes. Energy and macronutrient consumption remained below the recommendations and had an upward trend during hospitalization. Conclusion: The presence of cerebral calcification, the severity of microcephaly and symptomatic maternal exposure to Zika virus affected the nutritional status of newborns. In terms of nutritional factors, human milk intake had a positive impact, reducing weight loss in the first days of life. Other known factors, such as income and maternal schooling, were still associated with a poor nutritional status.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/45526/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINAL1807-5932-clin-74-e798.pdf1807-5932-clin-74-e798.pdfapplication/pdf825404https://www.arca.fiocruz.br/bitstream/icict/45526/2/1807-5932-clin-74-e798.pdf49f3be860a41c065fffddfbebe0b3d0cMD52TEXT1807-5932-clin-74-e798.pdf.txt1807-5932-clin-74-e798.pdf.txtExtracted texttext/plain35050https://www.arca.fiocruz.br/bitstream/icict/45526/3/1807-5932-clin-74-e798.pdf.txt9f6eeff2d07e5923e2172a3d4d05195fMD53icict/455262021-01-08 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| dc.title.pt_BR.fl_str_mv |
Nutritional profile of newborns with microcephaly and factors associated with worse outcomes |
| title |
Nutritional profile of newborns with microcephaly and factors associated with worse outcomes |
| spellingShingle |
Nutritional profile of newborns with microcephaly and factors associated with worse outcomes Santos, Samira Fernandes Morais dos Adolescent Adult Female Humans Infant, Newborn Longitudinal Studies Male Microcephaly / physiopathology Microcephaly / virology Nutritional Status / physiology Risk Factors Severity of Illness Index Socioeconomic Factors Young Adult Zika Virus Infection / complications Zika Virus Microcephaly Nutritional Status Newborn |
| title_short |
Nutritional profile of newborns with microcephaly and factors associated with worse outcomes |
| title_full |
Nutritional profile of newborns with microcephaly and factors associated with worse outcomes |
| title_fullStr |
Nutritional profile of newborns with microcephaly and factors associated with worse outcomes |
| title_full_unstemmed |
Nutritional profile of newborns with microcephaly and factors associated with worse outcomes |
| title_sort |
Nutritional profile of newborns with microcephaly and factors associated with worse outcomes |
| author |
Santos, Samira Fernandes Morais dos |
| author_facet |
Santos, Samira Fernandes Morais dos Soares, Fernanda Valente Mendes Abranches, Andrea Dunshee de Costa, Ana Carolina Carioca da Gomes Junior, Saint Clair dos Santos Fonseca, Vania de Matos Moreira, Maria Elisabeth Lopes |
| author_role |
author |
| author2 |
Soares, Fernanda Valente Mendes Abranches, Andrea Dunshee de Costa, Ana Carolina Carioca da Gomes Junior, Saint Clair dos Santos Fonseca, Vania de Matos Moreira, Maria Elisabeth Lopes |
| author2_role |
author author author author author author |
| dc.contributor.author.fl_str_mv |
Santos, Samira Fernandes Morais dos Soares, Fernanda Valente Mendes Abranches, Andrea Dunshee de Costa, Ana Carolina Carioca da Gomes Junior, Saint Clair dos Santos Fonseca, Vania de Matos Moreira, Maria Elisabeth Lopes |
| dc.subject.mesh.pt_BR.fl_str_mv |
Adolescent Adult Female Humans Infant, Newborn Longitudinal Studies Male Microcephaly / physiopathology Microcephaly / virology Nutritional Status / physiology Risk Factors Severity of Illness Index Socioeconomic Factors Young Adult Zika Virus Infection / complications |
| topic |
Adolescent Adult Female Humans Infant, Newborn Longitudinal Studies Male Microcephaly / physiopathology Microcephaly / virology Nutritional Status / physiology Risk Factors Severity of Illness Index Socioeconomic Factors Young Adult Zika Virus Infection / complications Zika Virus Microcephaly Nutritional Status Newborn |
| dc.subject.en.pt_BR.fl_str_mv |
Zika Virus Microcephaly Nutritional Status Newborn |
| description |
Fundação Oswaldo Cruz. Instituto Nacional de Saúde da Mulher, da Criança e do Adolescente Fernandes Figueira. Rio de Janeiro, RJ, Brasil |
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2019 |
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2019 |
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2021-01-07T14:41:18Z |
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2021-01-07T14:41:18Z |
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info:eu-repo/semantics/publishedVersion |
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Dos Santos SFM, Soares FVM, de Abranches AD, da Costa ACC, Gomes-Júnior SCDS, Fonseca VM, Moreira MEL. Nutritional profile of newborns with microcephaly and factors associated with worse outcomes. Clinics (Sao Paulo). 2019 Oct 21;74:e798. doi: 10.6061/clinics/2019/e798. PMID: 31644665; PMCID: PMC6791297. |
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https://www.arca.fiocruz.br/handle/icict/45526 |
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1807-5932 |
| dc.identifier.doi.none.fl_str_mv |
10.6061/clinics/2019/e798 |
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Dos Santos SFM, Soares FVM, de Abranches AD, da Costa ACC, Gomes-Júnior SCDS, Fonseca VM, Moreira MEL. Nutritional profile of newborns with microcephaly and factors associated with worse outcomes. Clinics (Sao Paulo). 2019 Oct 21;74:e798. doi: 10.6061/clinics/2019/e798. PMID: 31644665; PMCID: PMC6791297. 1807-5932 10.6061/clinics/2019/e798 |
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Faculdade de Medicina - USP |
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Faculdade de Medicina - USP |
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