Rapid Tests and the Diagnosis of Visceral Leishmaniasis and Human Immunodeficiency Virus/Acquired Immunodeficiency Syndrome Coinfection

Detalhes bibliográficos
Autor(a) principal: Barbosa Júnior, Walter Lins
Data de Publicação: 2015
Outros Autores: Araújo, Paulo Sérgio Ramos de, Andrade, Luiz Dias de, Santos, Ana Maria Aguiar dos, Silva, Maria Almerice Lopes da, Dantas-Torres, Filipe, Medeiros, Zulma
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/21055
Resumo: Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Recife, PE, Brasil
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spelling Barbosa Júnior, Walter LinsAraújo, Paulo Sérgio Ramos deAndrade, Luiz Dias deSantos, Ana Maria Aguiar dosSilva, Maria Almerice Lopes daDantas-Torres, FilipeMedeiros, Zulma2017-09-19T13:16:54Z2017-09-19T13:16:54Z2015BARBOSA JÚNIOR, Walter Lins et al. Rapid Tests and the Diagnosis of Visceral Leishmaniasis and Human Immunodeficiency Virus/Acquired Immunodeficiency Syndrome Coinfection. The American Journal of Tropical Medicine and Hygiene, v. 93, n. 5, p. 967–969, nov. 2015.1476-1645https://www.arca.fiocruz.br/handle/icict/2105510.4269/ajtmh.14-0798porInfecções por HIVLeishmaniose VisceralAdultAgglutination TestsAntigens, ProtozoanBiomarkersCoinfectionFemaleHIV InfectionsHumansImmunochromatographyLatex Fixation TestsLeishmaniasis, VisceralMaleMiddle AgedProtozoan ProteinsReproducibility of ResultsSensitivity and SpecificityYoung AdultcomplicationsdiagnosismethodsInfecções por HIVLeishmaniose VisceralAdultoHumanosFemininoMasculinoTestes de AglutinaçãoBiomarcadoresCoinfecçãoInfecções por HIVImunocromatografiaTestes de Fixação do LátexProteínas de protozoáriosMeia-IdadeReprodutibilidade dos testesSensibilidade e EspecificidadeAdulto JovemRapid Tests and the Diagnosis of Visceral Leishmaniasis and Human Immunodeficiency Virus/Acquired Immunodeficiency Syndrome Coinfectioninfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Aggeu Magalhães. Recife, PE, BrasilAfter the emergence of the human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS), the number of visceral leishmaniasis (VL)-HIV/AIDS coinfections has increased worldwide. Herein, we assessed the usefulness of an rK39-based immunochromatographic test (rK39 ICT) (DiaMed-IT LEISH(®); DiaMed AG, Cressier-sur-Morat, Switzerland) and a latex agglutination test (KAtex; Kalon Biological, Guildford, United Kingdom) for urinary antigen detection to diagnose VL in 15 HIV/AIDS patients from northeastern Brazil. VL diagnosis was based on clinical findings, cytology, serology, parasite DNA, and/or urinary antigen detection. VL was confirmed in seven out of 15 HIV/AIDS patients. Only three patients were positive in bone marrow cytology, three patients were conventional polymerase chain reaction (PCR) positive, while six were real-time PCR positive. All patients were direct agglutination test (DAT) (Royal Tropical Institute, Amsterdam, The Netherlands) positive; of these, four were positive by rK39 ICT and five by KAtex. Large-scale studies are needed to validate the use of the KAtex in the national public health laboratory network in Brazil, aiming at improving the diagnosis of VL in HIV/AIDS patients in this country.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/21055/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINAL26416105 2015 bar-rap.oa.pdf26416105 2015 bar-rap.oa.pdfapplication/pdf451997https://www.arca.fiocruz.br/bitstream/icict/21055/2/26416105%202015%20bar-rap.oa.pdfbf05bca6f16455f119931a19a02f0eb6MD52TEXT26416105 2015 bar-rap.oa.pdf.txt26416105 2015 bar-rap.oa.pdf.txtExtracted texttext/plain20399https://www.arca.fiocruz.br/bitstream/icict/21055/3/26416105%202015%20bar-rap.oa.pdf.txte7ebc9579bd84b3159bdd2b6c38ed005MD53icict/210552018-08-15 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dc.title.pt_BR.fl_str_mv Rapid Tests and the Diagnosis of Visceral Leishmaniasis and Human Immunodeficiency Virus/Acquired Immunodeficiency Syndrome Coinfection
title Rapid Tests and the Diagnosis of Visceral Leishmaniasis and Human Immunodeficiency Virus/Acquired Immunodeficiency Syndrome Coinfection
spellingShingle Rapid Tests and the Diagnosis of Visceral Leishmaniasis and Human Immunodeficiency Virus/Acquired Immunodeficiency Syndrome Coinfection
Barbosa Júnior, Walter Lins
Infecções por HIV
Leishmaniose Visceral
Adult
Agglutination Tests
Antigens, Protozoan
Biomarkers
Coinfection
Female
HIV Infections
Humans
Immunochromatography
Latex Fixation Tests
Leishmaniasis, Visceral
Male
Middle Aged
Protozoan Proteins
Reproducibility of Results
Sensitivity and Specificity
Young Adult
complications
diagnosis
methods
Infecções por HIV
Leishmaniose Visceral
Adulto
Humanos
Feminino
Masculino
Testes de Aglutinação
Biomarcadores
Coinfecção
Infecções por HIV
Imunocromatografia
Testes de Fixação do Látex
Proteínas de protozoários
Meia-Idade
Reprodutibilidade dos testes
Sensibilidade e Especificidade
Adulto Jovem
title_short Rapid Tests and the Diagnosis of Visceral Leishmaniasis and Human Immunodeficiency Virus/Acquired Immunodeficiency Syndrome Coinfection
title_full Rapid Tests and the Diagnosis of Visceral Leishmaniasis and Human Immunodeficiency Virus/Acquired Immunodeficiency Syndrome Coinfection
title_fullStr Rapid Tests and the Diagnosis of Visceral Leishmaniasis and Human Immunodeficiency Virus/Acquired Immunodeficiency Syndrome Coinfection
title_full_unstemmed Rapid Tests and the Diagnosis of Visceral Leishmaniasis and Human Immunodeficiency Virus/Acquired Immunodeficiency Syndrome Coinfection
title_sort Rapid Tests and the Diagnosis of Visceral Leishmaniasis and Human Immunodeficiency Virus/Acquired Immunodeficiency Syndrome Coinfection
author Barbosa Júnior, Walter Lins
author_facet Barbosa Júnior, Walter Lins
Araújo, Paulo Sérgio Ramos de
Andrade, Luiz Dias de
Santos, Ana Maria Aguiar dos
Silva, Maria Almerice Lopes da
Dantas-Torres, Filipe
Medeiros, Zulma
author_role author
author2 Araújo, Paulo Sérgio Ramos de
Andrade, Luiz Dias de
Santos, Ana Maria Aguiar dos
Silva, Maria Almerice Lopes da
Dantas-Torres, Filipe
Medeiros, Zulma
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Barbosa Júnior, Walter Lins
Araújo, Paulo Sérgio Ramos de
Andrade, Luiz Dias de
Santos, Ana Maria Aguiar dos
Silva, Maria Almerice Lopes da
Dantas-Torres, Filipe
Medeiros, Zulma
dc.subject.other.pt_BR.fl_str_mv Infecções por HIV
Leishmaniose Visceral
topic Infecções por HIV
Leishmaniose Visceral
Adult
Agglutination Tests
Antigens, Protozoan
Biomarkers
Coinfection
Female
HIV Infections
Humans
Immunochromatography
Latex Fixation Tests
Leishmaniasis, Visceral
Male
Middle Aged
Protozoan Proteins
Reproducibility of Results
Sensitivity and Specificity
Young Adult
complications
diagnosis
methods
Infecções por HIV
Leishmaniose Visceral
Adulto
Humanos
Feminino
Masculino
Testes de Aglutinação
Biomarcadores
Coinfecção
Infecções por HIV
Imunocromatografia
Testes de Fixação do Látex
Proteínas de protozoários
Meia-Idade
Reprodutibilidade dos testes
Sensibilidade e Especificidade
Adulto Jovem
dc.subject.en.pt_BR.fl_str_mv Adult
Agglutination Tests
Antigens, Protozoan
Biomarkers
Coinfection
Female
HIV Infections
Humans
Immunochromatography
Latex Fixation Tests
Leishmaniasis, Visceral
Male
Middle Aged
Protozoan Proteins
Reproducibility of Results
Sensitivity and Specificity
Young Adult
complications
diagnosis
methods
dc.subject.decs.pt_BR.fl_str_mv Infecções por HIV
Leishmaniose Visceral
Adulto
Humanos
Feminino
Masculino
Testes de Aglutinação
Biomarcadores
Coinfecção
Infecções por HIV
Imunocromatografia
Testes de Fixação do Látex
Proteínas de protozoários
Meia-Idade
Reprodutibilidade dos testes
Sensibilidade e Especificidade
Adulto Jovem
description Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Recife, PE, Brasil
publishDate 2015
dc.date.issued.fl_str_mv 2015
dc.date.accessioned.fl_str_mv 2017-09-19T13:16:54Z
dc.date.available.fl_str_mv 2017-09-19T13:16:54Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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status_str publishedVersion
dc.identifier.citation.fl_str_mv BARBOSA JÚNIOR, Walter Lins et al. Rapid Tests and the Diagnosis of Visceral Leishmaniasis and Human Immunodeficiency Virus/Acquired Immunodeficiency Syndrome Coinfection. The American Journal of Tropical Medicine and Hygiene, v. 93, n. 5, p. 967–969, nov. 2015.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/21055
dc.identifier.issn.pt_BR.fl_str_mv 1476-1645
dc.identifier.doi.none.fl_str_mv 10.4269/ajtmh.14-0798
identifier_str_mv BARBOSA JÚNIOR, Walter Lins et al. Rapid Tests and the Diagnosis of Visceral Leishmaniasis and Human Immunodeficiency Virus/Acquired Immunodeficiency Syndrome Coinfection. The American Journal of Tropical Medicine and Hygiene, v. 93, n. 5, p. 967–969, nov. 2015.
1476-1645
10.4269/ajtmh.14-0798
url https://www.arca.fiocruz.br/handle/icict/21055
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