Congenital papillomas and papillomatoses associated with the human papilloma virus (HPV)-report on 5 cases

Detalhes bibliográficos
Autor(a) principal: Dias, Eliane Pedra
Data de Publicação: 1995
Outros Autores: Barcelos, Jose Maria Pinto, Fonseca, Evangelina Ferreira, Basso, Nádia Gomes da Silva
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/36609
Resumo: Introdução: Os autores apresentam um estudo de cinco casos de papilomas e papilomatoses vulvares congênitas em neo e nati-mortos. Material e Métodos: O material utilizado foi proveniente de cinco necrópsias. A avaliação histopatológica mostrou aspectos sugestivos de infecção pelo Pailomavirus humano (HPV). A microscopia eletrônica de três dos casos identificou partículas viróticas nucleares e citoplasmáticas variando de 40 a 60 nm, compatíveis com HPV. Resultados: O estudo imunohistoquímico destas lesões demonstrou imunopositividade citoplasmática e nuclear. Conclusão: Os autores concluíram que a presença de partículas viróticas somada a imunopositividade em células escamosas, são evidências do provável envolvimento etiológico do HPV nestas lesões.
id CRUZ_5cab125f07973f760e013e1e09ba871e
oai_identifier_str oai:www.arca.fiocruz.br:icict/36609
network_acronym_str CRUZ
network_name_str Repositório Institucional da FIOCRUZ (ARCA)
repository_id_str 2135
spelling Dias, Eliane PedraBarcelos, Jose Maria PintoFonseca, Evangelina FerreiraBasso, Nádia Gomes da Silva2019-10-21T16:55:10Z2019-10-21T16:55:10Z1995DIAS, Eliane Pedra et al. Congenital papillomas and papillomatoses associated with the Human Papilloma Virus (HPV): report on 5 cases. São Paulo Medical Journal, v. 113, n. 4, p. 957-963, 1995.1516-3180https://www.arca.fiocruz.br/handle/icict/3660910.1590/s1516-31801995000400007Introdução: Os autores apresentam um estudo de cinco casos de papilomas e papilomatoses vulvares congênitas em neo e nati-mortos. Material e Métodos: O material utilizado foi proveniente de cinco necrópsias. A avaliação histopatológica mostrou aspectos sugestivos de infecção pelo Pailomavirus humano (HPV). A microscopia eletrônica de três dos casos identificou partículas viróticas nucleares e citoplasmáticas variando de 40 a 60 nm, compatíveis com HPV. Resultados: O estudo imunohistoquímico destas lesões demonstrou imunopositividade citoplasmática e nuclear. Conclusão: Os autores concluíram que a presença de partículas viróticas somada a imunopositividade em células escamosas, são evidências do provável envolvimento etiológico do HPV nestas lesões.The authors present a study of five cases of vulvar congenital papillomas and papillomatoses in stillborns and neonates dead upon birth. The studied material was collected from five necropsies. The histopathological evaluation showed hyperkeratosis, acanthosis, papillomatosis, perinuclear haloes, and nuclear abnormalities. In three of the cases, the electron microscopy identified nuclear and cytoplasmatic viral particles ranging from 40 to 60 nm in size, compatible with HPV. The immunohistochemical study of those lesions showed nuclear and cytoplasmatic positivity. The authors concluded that the presence of viral particles suggestive of HPV added to the immunopositivity indicated the possibility of viral infection.Universidade Federal Fluminense. Departamento de Patologia. Niterói, RJ, Brasil.Universidade do Rio de Janeiro. Departamento de Patologia. Rio de Janeiro, RJ, Brasil.Universidade Federal do Rio de Janeiro. Departamento de Virologia. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Fernandes Figueiras. Patologia Clínica. Rio de Janeiro, RJ, Brasil.engAssociação Paulista de MedicinaPapillomavirus InfectionsPregnancy Complications, InfectiousTumor Virus InfectionsVulvar DiseasesInfant NewbornPregnancyFemaleHumansCongenital PapillomaHPVPapillomatosisCongenital papillomas and papillomatoses associated with the human papilloma virus (HPV)-report on 5 casesinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/36609/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALCongenital papillomas and papillomatoses associated with the human papilloma virus (HPV)-report on 5 cases. v113n4a06.pdfCongenital papillomas and papillomatoses associated with the human papilloma virus (HPV)-report on 5 cases. v113n4a06.pdfapplication/pdf1518573https://www.arca.fiocruz.br/bitstream/icict/36609/2/Congenital%20papillomas%20and%20papillomatoses%20associated%20with%20the%20human%20papilloma%20virus%20%28HPV%29-report%20on%205%20cases.%20v113n4a06.pdfd4c1b4fb2167950a6a5c26e765c599c0MD52TEXTCongenital papillomas and papillomatoses associated with the human papilloma virus (HPV)-report on 5 cases. v113n4a06.pdf.txtCongenital papillomas and papillomatoses associated with the human papilloma virus (HPV)-report on 5 cases. v113n4a06.pdf.txtExtracted texttext/plain33110https://www.arca.fiocruz.br/bitstream/icict/36609/3/Congenital%20papillomas%20and%20papillomatoses%20associated%20with%20the%20human%20papilloma%20virus%20%28HPV%29-report%20on%205%20cases.%20v113n4a06.pdf.txteb3fa7e795f716227ca6b36fba5e7f44MD53icict/366092019-10-22 02:02:15.508oai:www.arca.fiocruz.br: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ório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352019-10-22T05:02:15Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.pt_BR.fl_str_mv Congenital papillomas and papillomatoses associated with the human papilloma virus (HPV)-report on 5 cases
title Congenital papillomas and papillomatoses associated with the human papilloma virus (HPV)-report on 5 cases
spellingShingle Congenital papillomas and papillomatoses associated with the human papilloma virus (HPV)-report on 5 cases
Dias, Eliane Pedra
Papillomavirus Infections
Pregnancy Complications, Infectious
Tumor Virus Infections
Vulvar Diseases
Infant Newborn
Pregnancy
Female
Humans
Congenital Papilloma
HPV
Papillomatosis
title_short Congenital papillomas and papillomatoses associated with the human papilloma virus (HPV)-report on 5 cases
title_full Congenital papillomas and papillomatoses associated with the human papilloma virus (HPV)-report on 5 cases
title_fullStr Congenital papillomas and papillomatoses associated with the human papilloma virus (HPV)-report on 5 cases
title_full_unstemmed Congenital papillomas and papillomatoses associated with the human papilloma virus (HPV)-report on 5 cases
title_sort Congenital papillomas and papillomatoses associated with the human papilloma virus (HPV)-report on 5 cases
author Dias, Eliane Pedra
author_facet Dias, Eliane Pedra
Barcelos, Jose Maria Pinto
Fonseca, Evangelina Ferreira
Basso, Nádia Gomes da Silva
author_role author
author2 Barcelos, Jose Maria Pinto
Fonseca, Evangelina Ferreira
Basso, Nádia Gomes da Silva
author2_role author
author
author
dc.contributor.author.fl_str_mv Dias, Eliane Pedra
Barcelos, Jose Maria Pinto
Fonseca, Evangelina Ferreira
Basso, Nádia Gomes da Silva
dc.subject.mesh.pt_BR.fl_str_mv Papillomavirus Infections
Pregnancy Complications, Infectious
Tumor Virus Infections
Vulvar Diseases
Infant Newborn
Pregnancy
Female
Humans
topic Papillomavirus Infections
Pregnancy Complications, Infectious
Tumor Virus Infections
Vulvar Diseases
Infant Newborn
Pregnancy
Female
Humans
Congenital Papilloma
HPV
Papillomatosis
dc.subject.en.pt_BR.fl_str_mv Congenital Papilloma
HPV
Papillomatosis
description Introdução: Os autores apresentam um estudo de cinco casos de papilomas e papilomatoses vulvares congênitas em neo e nati-mortos. Material e Métodos: O material utilizado foi proveniente de cinco necrópsias. A avaliação histopatológica mostrou aspectos sugestivos de infecção pelo Pailomavirus humano (HPV). A microscopia eletrônica de três dos casos identificou partículas viróticas nucleares e citoplasmáticas variando de 40 a 60 nm, compatíveis com HPV. Resultados: O estudo imunohistoquímico destas lesões demonstrou imunopositividade citoplasmática e nuclear. Conclusão: Os autores concluíram que a presença de partículas viróticas somada a imunopositividade em células escamosas, são evidências do provável envolvimento etiológico do HPV nestas lesões.
publishDate 1995
dc.date.issued.fl_str_mv 1995
dc.date.accessioned.fl_str_mv 2019-10-21T16:55:10Z
dc.date.available.fl_str_mv 2019-10-21T16:55:10Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv DIAS, Eliane Pedra et al. Congenital papillomas and papillomatoses associated with the Human Papilloma Virus (HPV): report on 5 cases. São Paulo Medical Journal, v. 113, n. 4, p. 957-963, 1995.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/36609
dc.identifier.issn.pt_BR.fl_str_mv 1516-3180
dc.identifier.doi.pt_BR.fl_str_mv 10.1590/s1516-31801995000400007
identifier_str_mv DIAS, Eliane Pedra et al. Congenital papillomas and papillomatoses associated with the Human Papilloma Virus (HPV): report on 5 cases. São Paulo Medical Journal, v. 113, n. 4, p. 957-963, 1995.
1516-3180
10.1590/s1516-31801995000400007
url https://www.arca.fiocruz.br/handle/icict/36609
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Associação Paulista de Medicina
publisher.none.fl_str_mv Associação Paulista de Medicina
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
bitstream.url.fl_str_mv https://www.arca.fiocruz.br/bitstream/icict/36609/1/license.txt
https://www.arca.fiocruz.br/bitstream/icict/36609/2/Congenital%20papillomas%20and%20papillomatoses%20associated%20with%20the%20human%20papilloma%20virus%20%28HPV%29-report%20on%205%20cases.%20v113n4a06.pdf
https://www.arca.fiocruz.br/bitstream/icict/36609/3/Congenital%20papillomas%20and%20papillomatoses%20associated%20with%20the%20human%20papilloma%20virus%20%28HPV%29-report%20on%205%20cases.%20v113n4a06.pdf.txt
bitstream.checksum.fl_str_mv 5a560609d32a3863062d77ff32785d58
d4c1b4fb2167950a6a5c26e765c599c0
eb3fa7e795f716227ca6b36fba5e7f44
bitstream.checksumAlgorithm.fl_str_mv MD5
MD5
MD5
repository.name.fl_str_mv Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)
repository.mail.fl_str_mv repositorio.arca@fiocruz.br
_version_ 1798324637461905408

Registros relacionados