Arbovirus investigation in patients from Mato Grosso during Zika andChikungunya virus introdution in Brazil, 2015–2016

Bibliographic Details
Main Author: Costa, M. C. de Souza
Publication Date: 2019
Other Authors: Maia, L. M. Siqueira, Souza, Valdinete Costa de, Gonzaga, A. M., Azevedo, V. Correa de, Martins, L. Ramos, Pavoni, J. H. Chavez, Naveca, Felipe Gomes, Slhessarenko, R. Dezengrini
Format: Article
Language: eng
Source: Repositório Institucional da FIOCRUZ (ARCA)
Download full: https://www.arca.fiocruz.br/handle/icict/31954
Summary: Fundação Oswaldo Cruz. Instituto de Pesquisas Leônidas e Maria Deane. Manaus, AM, Brasil.
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spelling Costa, M. C. de SouzaMaia, L. M. SiqueiraSouza, Valdinete Costa deGonzaga, A. M.Azevedo, V. Correa deMartins, L. RamosPavoni, J. H. ChavezNaveca, Felipe GomesSlhessarenko, R. Dezengrini2019-03-04T18:10:30Z2019-03-04T18:10:30Z2019COSTA, M. C. de Souza et al. Arbovirus investigation in patients from Mato Grosso during Zika and Chikungunya virus introdution in Brazil, 2015–2016. Acta Tropica, Philadelfia, v. 190, p. 395-402, feb. 2019.0001-706Xhttps://www.arca.fiocruz.br/handle/icict/3195410.1016/j.actatropica.2018.12.019engArbovirus investigation in patients from Mato Grosso during Zika andChikungunya virus introdution in Brazil, 2015–2016info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto de Pesquisas Leônidas e Maria Deane. Manaus, AM, Brasil.Universidade Federal de Mato Grosso. Faculdade de Medicina. Departamento de Ciências Básicas em Saúde. Programa de Pós-Graduação em Ciências da Saúde. Cuiabá, MT, Brasil.Universidade Federal de Mato Grosso. Faculdade de Medicina. Departamento de Ciências Básicas em Saúde. Programa de Pós-Graduação em Ciências da Saúde. Cuiabá, MT, Brasil.Fundação Oswaldo Cruz. Instituto Leônidas e Maria Deane. Manaus, AM, Brasil.Secretaria Estadual de Saúde. LACEN-MT. Cuiabá, MT, Brasil.Secretaria Estadual de Saúde. LACEN-MT. Cuiabá, MT, Brasil.Universidade Federal de Mato Grosso Graduação em Medicina Veterinária. Faculdade de Medicina Veterinária. Cuiabá, MT, Brasil.Universidade Federal de Mato Grosso. Faculdade de Medicina. Rondonópolis, MT, Brasil.Fundação Oswaldo Cruz. Instituto Leônidas e Maria Deane. Manaus, AM, Brasil.Universidade Federal de Mato Grosso. Faculdade de Medicina. Departamento de Ciências Básicas em Saúde. Programa de Pós-Graduação em Ciências da Saúde. Cuiabá, MT, Brasil.Arboviruses have become a major public health concern in Brazil, especially after Zika virus (ZIKV) and Chikungunya virus (CHIKV) introduction, leading to massive epidemics. We conducted an investigation of arboviruses in patients with acute febrile illness for less thanfive days in Mato Grosso state (MT) during the periodof ZIKV and CHIKV dissemination in Brazil. To achieve that, 453 human serum samples of patients suspected ofDengue (DENV), Yellow Fever (YFV), ZIKV or CHIKV collected in health units of 31 cities of MT were subjectedto RT-PCR protocols for 10flaviviruses, 5 alphaviruses and orthobunyaviruses from Simbu serogroup, nucleotidesequencing and viral isolation. Regardingflaviviruses,five (1.1%) patients were infected with DENV-1 genotypeV, 22 (4.4%) with DENV-4 genotype II, 3 (0.7%) with YFV South American genotype II andfive (1.1%) withZIKV Asian genotype. Thefirst human case of ZIKV in MT was detected in this study during August, 2015 in Tapurah. Alphaviruses were detected in 2 (0.4%) patients infected with CHIKV genotype ECSA, 1 (0.2%) withMadariaga (EEEV) lineage III and 34 (7.5%) with Mayaro (MAYV) genotype L. Four (11.4%) patients presenteddual infections with DENV-1/ZIKV, DENV-1/DENV4, DENV-4/MAYV and ZIKV/MAYV. The majority - 13/34positive for MAYV, one for Madariaga virus - are residents in Várzea Grande (VG), metropolitan region of Cuiabá, capital of MT. Thefirst CHIKV infection in MT was detected in this study in Mirassol D’Oeste, during July, 2015. In addition, 20 (4.4%) patients were positive for OROV Segment S genotype IA. These results re-inforce the variation in arboviruses frequency and distribution during outbreaks, highlinghing the importance ofdifferential diagnosis to identify agents silently co-circulating with major health problem arboviruses.Zika virusDengue virusChikungunya virusMayaro virusPublic healthEpidemiologyreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZinfo:eu-repo/semantics/openAccessLICENSElicense.txtlicense.txttext/plain; charset=utf-83082https://www.arca.fiocruz.br/bitstream/icict/31954/1/license.txt43cf57123dace9a28c9f6b2c996fa81bMD51ORIGINALArticle Arbovirus investigation in patients from Mato Grosso.pdfArticle Arbovirus investigation in patients from Mato Grosso.pdfapplication/pdf2738900https://www.arca.fiocruz.br/bitstream/icict/31954/2/Article%20Arbovirus%20investigation%20in%20patients%20from%20Mato%20Grosso.pdfb6dd6cdfcc0c0d8fac925b728f9a5edcMD52TEXTArticle Arbovirus investigation in patients from Mato 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dc.title.pt_BR.fl_str_mv Arbovirus investigation in patients from Mato Grosso during Zika andChikungunya virus introdution in Brazil, 2015–2016
title Arbovirus investigation in patients from Mato Grosso during Zika andChikungunya virus introdution in Brazil, 2015–2016
spellingShingle Arbovirus investigation in patients from Mato Grosso during Zika andChikungunya virus introdution in Brazil, 2015–2016
Costa, M. C. de Souza
Zika virus
Dengue virus
Chikungunya virus
Mayaro virus
Public health
Epidemiology
title_short Arbovirus investigation in patients from Mato Grosso during Zika andChikungunya virus introdution in Brazil, 2015–2016
title_full Arbovirus investigation in patients from Mato Grosso during Zika andChikungunya virus introdution in Brazil, 2015–2016
title_fullStr Arbovirus investigation in patients from Mato Grosso during Zika andChikungunya virus introdution in Brazil, 2015–2016
title_full_unstemmed Arbovirus investigation in patients from Mato Grosso during Zika andChikungunya virus introdution in Brazil, 2015–2016
title_sort Arbovirus investigation in patients from Mato Grosso during Zika andChikungunya virus introdution in Brazil, 2015–2016
author Costa, M. C. de Souza
author_facet Costa, M. C. de Souza
Maia, L. M. Siqueira
Souza, Valdinete Costa de
Gonzaga, A. M.
Azevedo, V. Correa de
Martins, L. Ramos
Pavoni, J. H. Chavez
Naveca, Felipe Gomes
Slhessarenko, R. Dezengrini
author_role author
author2 Maia, L. M. Siqueira
Souza, Valdinete Costa de
Gonzaga, A. M.
Azevedo, V. Correa de
Martins, L. Ramos
Pavoni, J. H. Chavez
Naveca, Felipe Gomes
Slhessarenko, R. Dezengrini
author2_role author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Costa, M. C. de Souza
Maia, L. M. Siqueira
Souza, Valdinete Costa de
Gonzaga, A. M.
Azevedo, V. Correa de
Martins, L. Ramos
Pavoni, J. H. Chavez
Naveca, Felipe Gomes
Slhessarenko, R. Dezengrini
dc.subject.en.pt_BR.fl_str_mv Zika virus
Dengue virus
Chikungunya virus
Mayaro virus
Public health
Epidemiology
topic Zika virus
Dengue virus
Chikungunya virus
Mayaro virus
Public health
Epidemiology
description Fundação Oswaldo Cruz. Instituto de Pesquisas Leônidas e Maria Deane. Manaus, AM, Brasil.
publishDate 2019
dc.date.accessioned.fl_str_mv 2019-03-04T18:10:30Z
dc.date.available.fl_str_mv 2019-03-04T18:10:30Z
dc.date.issued.fl_str_mv 2019
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv COSTA, M. C. de Souza et al. Arbovirus investigation in patients from Mato Grosso during Zika and Chikungunya virus introdution in Brazil, 2015–2016. Acta Tropica, Philadelfia, v. 190, p. 395-402, feb. 2019.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/31954
dc.identifier.issn.pt_BR.fl_str_mv 0001-706X
dc.identifier.doi.pt_BR.fl_str_mv 10.1016/j.actatropica.2018.12.019
identifier_str_mv COSTA, M. C. de Souza et al. Arbovirus investigation in patients from Mato Grosso during Zika and Chikungunya virus introdution in Brazil, 2015–2016. Acta Tropica, Philadelfia, v. 190, p. 395-402, feb. 2019.
0001-706X
10.1016/j.actatropica.2018.12.019
url https://www.arca.fiocruz.br/handle/icict/31954
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
bitstream.url.fl_str_mv https://www.arca.fiocruz.br/bitstream/icict/31954/1/license.txt
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