Evaluation of the EIE-IgM-Leptospirose assay for the serodiagnosis of leptospirosis.
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2007 |
| Outros Autores: | , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
| Texto Completo: | https://www.arca.fiocruz.br/handle/icict/7546 |
Resumo: | Fundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Salvador, BA, Brasil |
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McBride, Alan John AlexanderPereira, Fernanda AlbuquerqueSilva, Emilson Domingos daMatos, Rosan B. deSilva, Edimilson Domingos daFerreira, Antonio Gomes PintoReis, Mitermayer Galvão dosKo, Albert Icksang2014-04-25T18:49:40Z2014-04-25T18:49:40Z2007McBRIDE, A. j. A. et al. Evaluation of the EIE-IgM-Leptospirose assay for the serodiagnosis of leptospirosis. Acta Tropica, v. 102, n. 3, p. 206-211, 2007.0001-706Xhttps://www.arca.fiocruz.br/handle/icict/7546engNational Institute of HealthEvaluation of the EIE-IgM-Leptospirose assay for the serodiagnosis of leptospirosis.info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Salvador, BA, BrasilFundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Salvador, BA, BrasilFundação Oswaldo Cruz. Bio-Manguinhos. Rio de Janeiro, RJ, BrasilFundação Oswaldo Cruz. Bio-Manguinhos. Rio de Janeiro, RJ, BrasilFundação Oswaldo Cruz. Bio-Manguinhos. Rio de Janeiro, RJ, BrasilFundação Oswaldo Cruz. Bio-Manguinhos. Rio de Janeiro, RJ, BrasilFundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Salvador, BA, BrasilFundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Salvador, BA, Brasil / Division of International Medicine and Infectious Disease. Weill Medical College of Cornell University. New York, USAAccess to low-cost, effective diagnosis for leptospirosis is urgently needed in developing countries. The EIE-IgM-Leptospirose, a kit produced for public health laboratories in Brazil, was shown to have a sensitivity of 76% (77 of 102 patients) and 100% (102 of 102 patients) during acute and convalescent-phase leptospirosis, respectively, and a specificity of 93-100% (total healthy and patient control subjects evaluated, 486). These findings indicate that the assay will be useful for diagnosis of this emerging infectious disease in Brazil and other developing countries.IgM ELISADiagnosisEpidemicsUrbanserovarLeptospiraCopenhageniBrazilEnsaio de Imunoadsorção EnzimáticaImunoglobulina M/análiseLeptospirose/diagnósticoLeptospirose/imunologiaKit de Reagentes para DiagnósticoBrasil/epidemiologiaHumanosLeptospirose/epidemiologiaSensibilidade e EspecificidadeTestes Sorológicosinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZORIGINALMcBRIDE AJA Evaluation of the EIE-Igm......pdfMcBRIDE AJA Evaluation of the EIE-Igm......pdfapplication/pdf336093https://www.arca.fiocruz.br/bitstream/icict/7546/1/McBRIDE%20AJA%20Evaluation%20of%20the%20EIE-Igm......pdfe940bd79db5b0665ca7af5562adbd1e3MD51LICENSElicense.txtlicense.txttext/plain; charset=utf-81914https://www.arca.fiocruz.br/bitstream/icict/7546/2/license.txt7d48279ffeed55da8dfe2f8e81f3b81fMD52TEXTMcBRIDE AJA Evaluation of the EIE-Igm......pdf.txtMcBRIDE AJA Evaluation of the EIE-Igm......pdf.txtExtracted texttext/plain27414https://www.arca.fiocruz.br/bitstream/icict/7546/5/McBRIDE%20AJA%20Evaluation%20of%20the%20EIE-Igm......pdf.txtacfdc677903990f4174a5a4217e79782MD55THUMBNAILMcBRIDE AJA Evaluation of the EIE-Igm......pdf.jpgMcBRIDE AJA Evaluation of the EIE-Igm......pdf.jpgGenerated Thumbnailimage/jpeg2420https://www.arca.fiocruz.br/bitstream/icict/7546/4/McBRIDE%20AJA%20Evaluation%20of%20the%20EIE-Igm......pdf.jpg90349154b34a5d1cd9b61160947a68c1MD54icict/75462023-03-15 14:33:18.944oai:www.arca.fiocruz.br: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ório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352023-03-15T17:33:18Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false |
| dc.title.pt_BR.fl_str_mv |
Evaluation of the EIE-IgM-Leptospirose assay for the serodiagnosis of leptospirosis. |
| title |
Evaluation of the EIE-IgM-Leptospirose assay for the serodiagnosis of leptospirosis. |
| spellingShingle |
Evaluation of the EIE-IgM-Leptospirose assay for the serodiagnosis of leptospirosis. McBride, Alan John Alexander IgM ELISA Diagnosis Epidemics Urban serovar Leptospira Copenhageni Brazil Ensaio de Imunoadsorção Enzimática Imunoglobulina M/análise Leptospirose/diagnóstico Leptospirose/imunologia Kit de Reagentes para Diagnóstico Brasil/epidemiologia Humanos Leptospirose/epidemiologia Sensibilidade e Especificidade Testes Sorológicos |
| title_short |
Evaluation of the EIE-IgM-Leptospirose assay for the serodiagnosis of leptospirosis. |
| title_full |
Evaluation of the EIE-IgM-Leptospirose assay for the serodiagnosis of leptospirosis. |
| title_fullStr |
Evaluation of the EIE-IgM-Leptospirose assay for the serodiagnosis of leptospirosis. |
| title_full_unstemmed |
Evaluation of the EIE-IgM-Leptospirose assay for the serodiagnosis of leptospirosis. |
| title_sort |
Evaluation of the EIE-IgM-Leptospirose assay for the serodiagnosis of leptospirosis. |
| author |
McBride, Alan John Alexander |
| author_facet |
McBride, Alan John Alexander Pereira, Fernanda Albuquerque Silva, Emilson Domingos da Matos, Rosan B. de Silva, Edimilson Domingos da Ferreira, Antonio Gomes Pinto Reis, Mitermayer Galvão dos Ko, Albert Icksang |
| author_role |
author |
| author2 |
Pereira, Fernanda Albuquerque Silva, Emilson Domingos da Matos, Rosan B. de Silva, Edimilson Domingos da Ferreira, Antonio Gomes Pinto Reis, Mitermayer Galvão dos Ko, Albert Icksang |
| author2_role |
author author author author author author author |
| dc.contributor.author.fl_str_mv |
McBride, Alan John Alexander Pereira, Fernanda Albuquerque Silva, Emilson Domingos da Matos, Rosan B. de Silva, Edimilson Domingos da Ferreira, Antonio Gomes Pinto Reis, Mitermayer Galvão dos Ko, Albert Icksang |
| dc.subject.en.pt_BR.fl_str_mv |
IgM ELISA Diagnosis Epidemics Urban serovar Leptospira Copenhageni Brazil |
| topic |
IgM ELISA Diagnosis Epidemics Urban serovar Leptospira Copenhageni Brazil Ensaio de Imunoadsorção Enzimática Imunoglobulina M/análise Leptospirose/diagnóstico Leptospirose/imunologia Kit de Reagentes para Diagnóstico Brasil/epidemiologia Humanos Leptospirose/epidemiologia Sensibilidade e Especificidade Testes Sorológicos |
| dc.subject.decs.pt_BR.fl_str_mv |
Ensaio de Imunoadsorção Enzimática Imunoglobulina M/análise Leptospirose/diagnóstico Leptospirose/imunologia Kit de Reagentes para Diagnóstico Brasil/epidemiologia Humanos Leptospirose/epidemiologia Sensibilidade e Especificidade Testes Sorológicos |
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Fundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Salvador, BA, Brasil |
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2007 |
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2007 |
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2014-04-25T18:49:40Z |
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2014-04-25T18:49:40Z |
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info:eu-repo/semantics/article |
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McBRIDE, A. j. A. et al. Evaluation of the EIE-IgM-Leptospirose assay for the serodiagnosis of leptospirosis. Acta Tropica, v. 102, n. 3, p. 206-211, 2007. |
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https://www.arca.fiocruz.br/handle/icict/7546 |
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0001-706X |
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McBRIDE, A. j. A. et al. Evaluation of the EIE-IgM-Leptospirose assay for the serodiagnosis of leptospirosis. Acta Tropica, v. 102, n. 3, p. 206-211, 2007. 0001-706X |
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National Institute of Health |
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National Institute of Health |
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