Endocrine disruptors, estrogenic activity by the YES bioassay, and acute toxicity in Southeastern Brazil metropolitan surface waters

Detalhes bibliográficos
Autor(a) principal: Nascimento, Marilia Teresa Lima do
Data de Publicação: 2022
Outros Autores: Santos, Ana Dalva de Oliveira, Cunha, Danieli Lima da, Felix, Louise Cruz, Gomes, Giselle, Rangel, Carlos Marclei Arruda, Hauser-Davis, Rachel Ann, Fonseca, Estefan Monteiro da, Bila, Daniele Maia, Baptista Neto, José Antônio
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/53906
Resumo: Universidade Federal Fluminense. Instituto de Geociências. Departamento de Geologia. Niterói, RJ, Brasil.
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spelling Nascimento, Marilia Teresa Lima doSantos, Ana Dalva de OliveiraCunha, Danieli Lima daFelix, Louise CruzGomes, GiselleRangel, Carlos Marclei ArrudaHauser-Davis, Rachel AnnFonseca, Estefan Monteiro daBila, Daniele MaiaBaptista Neto, José Antônio2022-07-21T18:41:27Z2022-07-21T18:41:27Z2022NASCIMENTO, Maria Teresa Lima do et al. Endocrine disruptors, estrogenic activity by the YES bioassay, and acute toxicity in Southeastern Brazil metropolitan surface waters. Geochimíca Brasiliensis, v. 36, e-22005, p. 1 - 14, 2022.2358-2812https://www.arca.fiocruz.br/handle/icict/5390610.21715/GB2358-2812.202236005engSociedade Brasileira de GeoquímicaAtividade estrogênicaDesreguladores endócrinosBioensaio YESEnsaios de toxicidadeEstrogenic activityEndocrine disruptersYES bioassayToxicity assaysEndocrine disruptors, estrogenic activity by the YES bioassay, and acute toxicity in Southeastern Brazil metropolitan surface watersinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleUniversidade Federal Fluminense. Instituto de Geociências. Departamento de Geologia. Niterói, RJ, Brasil.Universidade Federal Fluminense. Instituto de Geociências. Departamento de Geologia. Niterói, RJ, Brasil.Universidade Federal Fluminense. Instituto de Geociências. Departamento de Geologia. Niterói, RJ, Brasil.Universidade do Estado do Rio de Janeiro. Departamento de Engenharia Sanitária e Ambiental. Rio de Janeiro, RJ, Brasil.Universidade do Estado do Rio de Janeiro. Departamento de Engenharia Sanitária e Ambiental. Rio de Janeiro, RJ, Brasil.Universidade Federal Fluminense. Instituto de Geociências. Departamento de Geologia. Niterói, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil.Universidade Federal Fluminense. Instituto de Geociências. Departamento de Geologia. Niterói, RJ, Brasil.Universidade do Estado do Rio de Janeiro. Departamento de Engenharia Sanitária e Ambiental. Rio de Janeiro, RJ, Brasil.Universidade Federal Fluminense. Instituto de Geociências. Departamento de Geologia. Niterói, RJ, Brasil.This study aimed to determine endocrine disruptors in urbanized rivers Maracanã and Mangue Channel in Rio de Janeiro the second most populated city in Brazil. Bisphenol A, 17β-estradiol, estriol, and 17α-ethinylestradiol were determined by high-performance liquid chromatography with a diode array detector and fluorescence detector In addition, the evaluation of estrogenic activity was performed by the YES bioassay (Yeast estrogen screen) with the Saccharomyces cerevisiae yeast, and acute toxicity assays were performed using Daphnia similis and Vibrio fischeri. Estrogenic activity in the water samples ranged from below the limit of detection (<LD) to 1.6 ng L-1, while bisphenol A ranged from 22.3 to 1325.2 ng L-1 and estrogens 17β- estradiol from <LD to 55.2 ng L-1, estriol from <LD to 313.7 ng L-1 and 17α- ethinylestradiol, from <LD to 409.4 ng L-1. The acute toxicity was not detected in both analyzed organisms. The present study indicates a serious level of pollution by the compounds evaluated with significant risks to the aquatic ecosystem, mainly for Guanabara Bay which receives urbanized river discharge. Therefore, recommending the need for systematic monitoring and mitigating actions in these water bodies.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZORIGINALMariliaNascimento_RachelHDavis_etal_IOC_2022.pdfMariliaNascimento_RachelHDavis_etal_IOC_2022.pdfapplication/pdf570812https://www.arca.fiocruz.br/bitstream/icict/53906/2/MariliaNascimento_RachelHDavis_etal_IOC_2022.pdf5bc070087b6d481049ba5f5d58fec95cMD52LICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/53906/1/license.txt5a560609d32a3863062d77ff32785d58MD51icict/539062022-07-21 15:41:27.341oai:www.arca.fiocruz.br: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ório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352022-07-21T18:41:27Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.pt_BR.fl_str_mv Endocrine disruptors, estrogenic activity by the YES bioassay, and acute toxicity in Southeastern Brazil metropolitan surface waters
title Endocrine disruptors, estrogenic activity by the YES bioassay, and acute toxicity in Southeastern Brazil metropolitan surface waters
spellingShingle Endocrine disruptors, estrogenic activity by the YES bioassay, and acute toxicity in Southeastern Brazil metropolitan surface waters
Nascimento, Marilia Teresa Lima do
Atividade estrogênica
Desreguladores endócrinos
Bioensaio YES
Ensaios de toxicidade
Estrogenic activity
Endocrine disrupters
YES bioassay
Toxicity assays
title_short Endocrine disruptors, estrogenic activity by the YES bioassay, and acute toxicity in Southeastern Brazil metropolitan surface waters
title_full Endocrine disruptors, estrogenic activity by the YES bioassay, and acute toxicity in Southeastern Brazil metropolitan surface waters
title_fullStr Endocrine disruptors, estrogenic activity by the YES bioassay, and acute toxicity in Southeastern Brazil metropolitan surface waters
title_full_unstemmed Endocrine disruptors, estrogenic activity by the YES bioassay, and acute toxicity in Southeastern Brazil metropolitan surface waters
title_sort Endocrine disruptors, estrogenic activity by the YES bioassay, and acute toxicity in Southeastern Brazil metropolitan surface waters
author Nascimento, Marilia Teresa Lima do
author_facet Nascimento, Marilia Teresa Lima do
Santos, Ana Dalva de Oliveira
Cunha, Danieli Lima da
Felix, Louise Cruz
Gomes, Giselle
Rangel, Carlos Marclei Arruda
Hauser-Davis, Rachel Ann
Fonseca, Estefan Monteiro da
Bila, Daniele Maia
Baptista Neto, José Antônio
author_role author
author2 Santos, Ana Dalva de Oliveira
Cunha, Danieli Lima da
Felix, Louise Cruz
Gomes, Giselle
Rangel, Carlos Marclei Arruda
Hauser-Davis, Rachel Ann
Fonseca, Estefan Monteiro da
Bila, Daniele Maia
Baptista Neto, José Antônio
author2_role author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Nascimento, Marilia Teresa Lima do
Santos, Ana Dalva de Oliveira
Cunha, Danieli Lima da
Felix, Louise Cruz
Gomes, Giselle
Rangel, Carlos Marclei Arruda
Hauser-Davis, Rachel Ann
Fonseca, Estefan Monteiro da
Bila, Daniele Maia
Baptista Neto, José Antônio
dc.subject.other.pt_BR.fl_str_mv Atividade estrogênica
Desreguladores endócrinos
Bioensaio YES
Ensaios de toxicidade
topic Atividade estrogênica
Desreguladores endócrinos
Bioensaio YES
Ensaios de toxicidade
Estrogenic activity
Endocrine disrupters
YES bioassay
Toxicity assays
dc.subject.en.pt_BR.fl_str_mv Estrogenic activity
Endocrine disrupters
YES bioassay
Toxicity assays
description Universidade Federal Fluminense. Instituto de Geociências. Departamento de Geologia. Niterói, RJ, Brasil.
publishDate 2022
dc.date.accessioned.fl_str_mv 2022-07-21T18:41:27Z
dc.date.available.fl_str_mv 2022-07-21T18:41:27Z
dc.date.issued.fl_str_mv 2022
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv NASCIMENTO, Maria Teresa Lima do et al. Endocrine disruptors, estrogenic activity by the YES bioassay, and acute toxicity in Southeastern Brazil metropolitan surface waters. Geochimíca Brasiliensis, v. 36, e-22005, p. 1 - 14, 2022.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/53906
dc.identifier.issn.pt_BR.fl_str_mv 2358-2812
dc.identifier.doi.none.fl_str_mv 10.21715/GB2358-2812.202236005
identifier_str_mv NASCIMENTO, Maria Teresa Lima do et al. Endocrine disruptors, estrogenic activity by the YES bioassay, and acute toxicity in Southeastern Brazil metropolitan surface waters. Geochimíca Brasiliensis, v. 36, e-22005, p. 1 - 14, 2022.
2358-2812
10.21715/GB2358-2812.202236005
url https://www.arca.fiocruz.br/handle/icict/53906
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Sociedade Brasileira de Geoquímica
publisher.none.fl_str_mv Sociedade Brasileira de Geoquímica
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
bitstream.url.fl_str_mv https://www.arca.fiocruz.br/bitstream/icict/53906/2/MariliaNascimento_RachelHDavis_etal_IOC_2022.pdf
https://www.arca.fiocruz.br/bitstream/icict/53906/1/license.txt
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repository.name.fl_str_mv Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)
repository.mail.fl_str_mv repositorio.arca@fiocruz.br
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