Risk factors for hospitalization and death due to COVID-19 among frail community-dwelling elderly people: a retrospective cohort study

Detalhes bibliográficos
Autor(a) principal: Azevedo, Daniela Castelo
Data de Publicação: 2022
Outros Autores: Assunção, Fernando César Menezes, Castro, Mônica Silva Monteiro de, Valle, Estevão Alves
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/56835
Resumo: Clínica Mais 60 Saúde. Belo Horizonte, MG, Brazil.
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spelling Azevedo, Daniela CasteloAssunção, Fernando César MenezesCastro, Mônica Silva Monteiro deValle, Estevão Alves2023-02-02T16:16:10Z2023-02-02T16:16:10Z2022AZEVEDO, Daniela Castelo et al. Risk factors for hospitalization and death due to COVID-19 among frail community-dwelling elderly people: a retrospective cohort study. Sao Paulo Med J., v. 140, n. 5, p. 676-681, 2022. doi: 10.1590/1516-3180.2021.0649.1516-3180https://www.arca.fiocruz.br/handle/icict/56835engAssociação Paulista de MedicinaFrail elderlyHospitalization, COVID-19Risk factorsFrailtyOlder adultsCommunity-dwelling elderlySARS-CoV-2 virusRisk factors for hospitalization and death due to COVID-19 among frail community-dwelling elderly people: a retrospective cohort studyinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleClínica Mais 60 Saúde. Belo Horizonte, MG, Brazil.Clínica Mais 60 Saúde. Belo Horizonte, MG, Brazil/LifeCodeTM Information System. Belo Horizonte, MG, Brazil.Health Policy and Social Protection Research Group. René Rachou Institute. Oswaldo Cruz Foundation. Belo Horizonte, MG, Brazil.Clínica Mais 60 Saúde. Belo Horizonte, MG, Brazil.Background: Advanced age, multiple chronic diseases and frailty have been correlated with worse prognosis among coronavirus disease 2019 (COVID-19) inpatients. Objective: To investigate potential risk factors for hospitalization and death due to COVID-19 among frail community-dwelling elderly people. Design and setting: Retrospective cohort study of patients followed up at a geriatric outpatient clinic in Belo Horizonte, Minas Gerais, Brazil. Methods: The associations of demographic characteristics (age and sex) and clinical characteristics (frailty, multimorbidity, number of medications with long-term use, obesity, smoking, diabetes mellitus, pulmonary diseases, cardiovascular diseases, cerebrovascular disease, and chronic kidney disease) with the risk of hospitalization and death due to COVID-19 were explored using a multivariable logistic regression model. Results: 5,295 patients (mean age 78.6 ± 9.4 years; 72.6% females) were included. After adjustments, the number of medications with long-term use was found to increase the odds of hospitalization due to COVID-19 (odds ratio, OR: 1.13; 95% confidence interval, CI: 1.06-1.22). Frailty, multimorbidity and diabetes mellitus also increased the odds of hospitalization (OR: 1.06, 95% CI: 1.02-1.09; OR: 1.17, 95% CI: 1.09-1.26; and OR: 2.27, 95% CI: 1.45-3.54, respectively) and the odds of death due to COVID-19 (OR: 1.07, 95% CI: 1.00-1.14; OR: 1.16, 95% CI: 1.03-1.32; and OR: 2.69, 95% CI: 1.79-6.14, respectively). Conclusions: Multimorbidity, frailty and diabetes mellitus increased the odds of hospitalization and death due to COVID-19 and the number of medications with long-term use increased the odds of hospitalization due to COVID-19 among frail community-dwelling elderly people.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/56835/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALRisk factors for hospitalization and death due.pdfRisk factors for hospitalization and death due.pdfapplication/pdf363525https://www.arca.fiocruz.br/bitstream/icict/56835/2/Risk%20factors%20for%20hospitalization%20and%20death%20due.pdfabd39884bdebcc8960b3da9b2a0f688cMD52icict/568352023-02-02 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dc.title.en_US.fl_str_mv Risk factors for hospitalization and death due to COVID-19 among frail community-dwelling elderly people: a retrospective cohort study
title Risk factors for hospitalization and death due to COVID-19 among frail community-dwelling elderly people: a retrospective cohort study
spellingShingle Risk factors for hospitalization and death due to COVID-19 among frail community-dwelling elderly people: a retrospective cohort study
Azevedo, Daniela Castelo
Frail elderly
Hospitalization
, COVID-19
Risk factors
Frailty
Older adults
Community-dwelling elderly
SARS-CoV-2 virus
title_short Risk factors for hospitalization and death due to COVID-19 among frail community-dwelling elderly people: a retrospective cohort study
title_full Risk factors for hospitalization and death due to COVID-19 among frail community-dwelling elderly people: a retrospective cohort study
title_fullStr Risk factors for hospitalization and death due to COVID-19 among frail community-dwelling elderly people: a retrospective cohort study
title_full_unstemmed Risk factors for hospitalization and death due to COVID-19 among frail community-dwelling elderly people: a retrospective cohort study
title_sort Risk factors for hospitalization and death due to COVID-19 among frail community-dwelling elderly people: a retrospective cohort study
author Azevedo, Daniela Castelo
author_facet Azevedo, Daniela Castelo
Assunção, Fernando César Menezes
Castro, Mônica Silva Monteiro de
Valle, Estevão Alves
author_role author
author2 Assunção, Fernando César Menezes
Castro, Mônica Silva Monteiro de
Valle, Estevão Alves
author2_role author
author
author
dc.contributor.author.fl_str_mv Azevedo, Daniela Castelo
Assunção, Fernando César Menezes
Castro, Mônica Silva Monteiro de
Valle, Estevão Alves
dc.subject.mesh.en_US.fl_str_mv Frail elderly
Hospitalization
, COVID-19
Risk factors
Frailty
topic Frail elderly
Hospitalization
, COVID-19
Risk factors
Frailty
Older adults
Community-dwelling elderly
SARS-CoV-2 virus
dc.subject.en.en_US.fl_str_mv Older adults
Community-dwelling elderly
SARS-CoV-2 virus
description Clínica Mais 60 Saúde. Belo Horizonte, MG, Brazil.
publishDate 2022
dc.date.issued.fl_str_mv 2022
dc.date.accessioned.fl_str_mv 2023-02-02T16:16:10Z
dc.date.available.fl_str_mv 2023-02-02T16:16:10Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv AZEVEDO, Daniela Castelo et al. Risk factors for hospitalization and death due to COVID-19 among frail community-dwelling elderly people: a retrospective cohort study. Sao Paulo Med J., v. 140, n. 5, p. 676-681, 2022. doi: 10.1590/1516-3180.2021.0649.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/56835
dc.identifier.issn.en_US.fl_str_mv 1516-3180
identifier_str_mv AZEVEDO, Daniela Castelo et al. Risk factors for hospitalization and death due to COVID-19 among frail community-dwelling elderly people: a retrospective cohort study. Sao Paulo Med J., v. 140, n. 5, p. 676-681, 2022. doi: 10.1590/1516-3180.2021.0649.
1516-3180
url https://www.arca.fiocruz.br/handle/icict/56835
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Associação Paulista de Medicina
publisher.none.fl_str_mv Associação Paulista de Medicina
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
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instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
bitstream.url.fl_str_mv https://www.arca.fiocruz.br/bitstream/icict/56835/1/license.txt
https://www.arca.fiocruz.br/bitstream/icict/56835/2/Risk%20factors%20for%20hospitalization%20and%20death%20due.pdf
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