Poverty, sanitation, and Leptospira transmission pathways in residents from four brazilian slums

Detalhes bibliográficos
Autor(a) principal: Khalil, Hussein
Data de Publicação: 2021
Outros Autores: Santana, Roberta, Oliveira, Daiana de, PalmaI, Fabiana, LustosaI, Ricardo, EyreI, Max T., Pereira, Ticiana Carvalho, Reis, Mitermayer Galvão dos, Ko, Albert Icksang, Diggle, Peter J., Lopez, Yeimi Alzate, BegonI, Mike, Costa, Federico
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/47654
Resumo: Medical Research Council (UK). Grant number: MR/P024084/1
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spelling Khalil, HusseinSantana, RobertaOliveira, Daiana dePalmaI, FabianaLustosaI, RicardoEyreI, Max T.Pereira, Ticiana CarvalhoReis, Mitermayer Galvão dosKo, Albert IcksangDiggle, Peter J.Lopez, Yeimi AlzateBegonI, MikeCosta, Federico2021-06-12T11:35:25Z2021-06-12T11:35:25Z2021KAHLIL, Hussein et al. Poverty, sanitation, and Leptospira transmission pathways in residents from four brazilian slums. PLoS Neglected Tropical Diseases, v. 15, n. 3, p. 1-15, 31 Mar. 2021.1935-2735https://www.arca.fiocruz.br/handle/icict/4765410.1371/journal.pntd.0009256Medical Research Council (UK). Grant number: MR/P024084/1Fundação de Amparo à Pesquisa do Estado da Bahia (BR) Grant number: 10206/2015Wellcome Trust (UK) Grant number: 102330/Z/13/ZNational Institutes of Health (US) Grant number:1 R01 TW009504 to FCUniversidade Federal da Bahia. Instituto de Saúde Coletiva. Salvador, BA, Brasil / Swedish University of Agricultural Sciences. Umeå, Sweden.Universidade Federal da Bahia. Instituto de Saúde Coletiva. Salvador, BA, Brasil.Universidade Federal da Bahia. Instituto de Saúde Coletiva. Salvador, BA, Brasil / Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil.Universidade Federal da Bahia. Instituto de Saúde Coletiva. Salvador, BA, Brasil.Universidade Federal da Bahia. Instituto de Saúde Coletiva. Salvador, BA, Brasil.Lancaster University. Lancaster Medical School. Centre for Health Informatics, Computing, and Statistics. Lancaster, United Kingdom.Universidade Federal da Bahia. Instituto de Saúde Coletiva. Salvador, BA, Brasil.Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil / Universidade Federal da Bahia. Faculdade de Medicina da Bahia. Salvador, BA, Brasil / Yale School of Public Health. Department of Epidemiology of Microbial Diseases. New Haven, USA.Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil / Yale School of Public Health. Department of Epidemiology of Microbial Diseases. New Haven, USA.Lancaster University. Lancaster Medical School. Centre for Health Informatics, Computing, and Statistics. Lancaster, United Kingdom.Universidade Federal da Bahia. Instituto de Saúde Coletiva. Salvador, BA, Brasil.University of Liverpool. Institute of Integrative Biology. Department of Evolution, Ecology and Behaviour. Liverpool, United Kingdom.Universidade Federal da Bahia. Instituto de Saúde Coletiva. Salvador, BA, Brasil / Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil / Yale School of Public Health. Department of Epidemiology of Microbial Diseases. New Haven, USA.Residents of urban slums suffer from a high burden of zoonotic diseases due to individual, socioeconomic, and environmental factors. We conducted a cross-sectional sero-survey in four urban slums in Salvador, Brazil, to characterize how poverty and sanitation contribute to the transmission of rat-borne leptospirosis. Sero-prevalence in the 1,318 participants ranged between 10.0 and 13.3%. We found that contact with environmental sources of contamination, rather than presence of rat reservoirs, is what leads to higher risk for residents living in areas with inadequate sanitation. Further, poorer residents may be exposed away from the household, and ongoing governmental interventions were not associated with lower transmission risk. Residents at higher risk were aware of their vulnerability, and their efforts improved the physical environment near their household, but did not reduce their infection chances. This study highlights the importance of understanding the socioeconomic and environmental determinants of risk, which ought to guide intervention efforts.engPublic Library of ScienceLeptospiraLeptospiroseMeio ambienteSaneamentoTransmissãoPrevalênciaLeptospiraLeptospirosisEnvironmentSanitationTransmissionPrevalencePoverty, sanitation, and Leptospira transmission pathways in residents from four brazilian slumsinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-83097https://www.arca.fiocruz.br/bitstream/icict/47654/1/license.txt36b51ef91c52b5338d9d29ba0cc807bcMD51ORIGINALKhalil, Hussein Poverty....pdfKhalil, Hussein 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dc.title.en.fl_str_mv Poverty, sanitation, and Leptospira transmission pathways in residents from four brazilian slums
title Poverty, sanitation, and Leptospira transmission pathways in residents from four brazilian slums
spellingShingle Poverty, sanitation, and Leptospira transmission pathways in residents from four brazilian slums
Khalil, Hussein
Leptospira
Leptospirose
Meio ambiente
Saneamento
Transmissão
Prevalência
Leptospira
Leptospirosis
Environment
Sanitation
Transmission
Prevalence
title_short Poverty, sanitation, and Leptospira transmission pathways in residents from four brazilian slums
title_full Poverty, sanitation, and Leptospira transmission pathways in residents from four brazilian slums
title_fullStr Poverty, sanitation, and Leptospira transmission pathways in residents from four brazilian slums
title_full_unstemmed Poverty, sanitation, and Leptospira transmission pathways in residents from four brazilian slums
title_sort Poverty, sanitation, and Leptospira transmission pathways in residents from four brazilian slums
author Khalil, Hussein
author_facet Khalil, Hussein
Santana, Roberta
Oliveira, Daiana de
PalmaI, Fabiana
LustosaI, Ricardo
EyreI, Max T.
Pereira, Ticiana Carvalho
Reis, Mitermayer Galvão dos
Ko, Albert Icksang
Diggle, Peter J.
Lopez, Yeimi Alzate
BegonI, Mike
Costa, Federico
author_role author
author2 Santana, Roberta
Oliveira, Daiana de
PalmaI, Fabiana
LustosaI, Ricardo
EyreI, Max T.
Pereira, Ticiana Carvalho
Reis, Mitermayer Galvão dos
Ko, Albert Icksang
Diggle, Peter J.
Lopez, Yeimi Alzate
BegonI, Mike
Costa, Federico
author2_role author
author
author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Khalil, Hussein
Santana, Roberta
Oliveira, Daiana de
PalmaI, Fabiana
LustosaI, Ricardo
EyreI, Max T.
Pereira, Ticiana Carvalho
Reis, Mitermayer Galvão dos
Ko, Albert Icksang
Diggle, Peter J.
Lopez, Yeimi Alzate
BegonI, Mike
Costa, Federico
dc.subject.other.pt_BR.fl_str_mv Leptospira
Leptospirose
Meio ambiente
Saneamento
Transmissão
Prevalência
topic Leptospira
Leptospirose
Meio ambiente
Saneamento
Transmissão
Prevalência
Leptospira
Leptospirosis
Environment
Sanitation
Transmission
Prevalence
dc.subject.en.en.fl_str_mv Leptospira
Leptospirosis
Environment
Sanitation
Transmission
Prevalence
description Medical Research Council (UK). Grant number: MR/P024084/1
publishDate 2021
dc.date.accessioned.fl_str_mv 2021-06-12T11:35:25Z
dc.date.available.fl_str_mv 2021-06-12T11:35:25Z
dc.date.issued.fl_str_mv 2021
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv KAHLIL, Hussein et al. Poverty, sanitation, and Leptospira transmission pathways in residents from four brazilian slums. PLoS Neglected Tropical Diseases, v. 15, n. 3, p. 1-15, 31 Mar. 2021.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/47654
dc.identifier.issn.pt_BR.fl_str_mv 1935-2735
dc.identifier.doi.pt_BR.fl_str_mv 10.1371/journal.pntd.0009256
identifier_str_mv KAHLIL, Hussein et al. Poverty, sanitation, and Leptospira transmission pathways in residents from four brazilian slums. PLoS Neglected Tropical Diseases, v. 15, n. 3, p. 1-15, 31 Mar. 2021.
1935-2735
10.1371/journal.pntd.0009256
url https://www.arca.fiocruz.br/handle/icict/47654
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Public Library of Science
publisher.none.fl_str_mv Public Library of Science
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
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