A proposed new clinical staging system for patients with mucosal leishmaniasis
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2012 |
| Outros Autores: | , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
| Texto Completo: | https://www.arca.fiocruz.br/handle/icict/19037 |
Resumo: | Arruda, Sérgio Marcos “Documento produzido em parceria ou por autor vinculado à Fiocruz, mas não consta à informação no documento”. |
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Lessa, Hélio AndradeLessa, Marcus MirandaGuimarães, Luiz Henrique SantosLima, Clara Mônica Figueiredo deArruda, Sérgio MarcosMachado, Paulo Roberto LimaCarvalho Filho, Edgar Marcelino2017-05-29T18:16:55Z2017-05-29T18:16:55Z2012LESSA, H. A. et al. A proposed new clinical staging system for patients with mucosal leishmaniasis. Transactions of The Royal Society of Tropical Medicine and Hygiene, v. 106, n. 6, p. 376–381, 2012.0035-9203https://www.arca.fiocruz.br/handle/icict/1903710.1016/j.trstmh.2012.03.007Arruda, Sérgio Marcos “Documento produzido em parceria ou por autor vinculado à Fiocruz, mas não consta à informação no documento”.US National Institutes of Health.Universidade Federal da Bahia. Complexo Hospitalar Universitário Professor Edgard Santos. Serviço de Imunologia. Salvador, BA, BrasilUniversidade Federal da Bahia. Complexo Hospitalar Universitário Professor Edgard Santos. Serviço de Imunologia. Salvador, BA, BrasilUniversidade Federal da Bahia. Complexo Hospitalar Universitário Professor Edgard Santos. Serviço de Imunologia. Salvador, BA, BrasilUniversidade Federal da Bahia. Complexo Hospitalar Universitário Professor Edgard Santos. Serviço de Imunologia. Salvador, BA, BrasilUniversidade Federal da Bahia. Complexo Hospitalar Universitário Professor Edgard Santos. Serviço de Imunologia. Salvador, BA, BrasilUniversidade Federal da Bahia. Complexo Hospitalar Universitário Professor Edgard Santos. Serviço de Imunologia. Salvador, BA, BrasilUniversidade Federal da Bahia. Complexo Hospitalar Universitário Professor Edgard Santos. Serviço de Imunologia. Salvador, BA, Brasil / Instituto Nacional de Ciência e Tecnologia de Doenças Tropicais. Salvador, BA, BrasilMucosal leishmaniasis (ML) occurs mainly in areas where Leishmania braziliensis is transmitted. It affects predominantly the nasal mucosa and, in more severe forms, can lead to significant tissue destruction. There is no standard method for grading the severity of disease. We categorised 50 patients with ML according to a proposed new clinical staging system. Their age ranged from 10 to 86 y (mean ± SD: 36 ± 16 y) and 43 (86%) patients were male. The different degrees of evolution of mucosal disease, from the initial stage to the more severe long-term cases, enabled ML to be graded into five stages. Stage I is characterised by nodular lesions of the mucosa without ulceration. Stage II is represented by superficial mucosal ulcerations with concomitant fine granular lesions. Stage III is characterised by deep mucosal ulcerations with granular tissue formation. In stage IV there are irreversible lesions leading to perforation of the cartilaginous nasal septum with necrosis. In stage V the nasal pyramid is compromised with alterations of facial features as a consequence of severe tissue destruction. These stages may be useful in characterising the severity of the lesion and optimising therapeutic outcome.engOxfor University PressLeishmanioseLeishmaniose mucosaEstágio da doençaMucosa nasalDoenças do narizBrasilLeishmaniasisMucosal leishmaniasisDisease stageNasal mucosaNose diseasesBrazilLeishmanioseMucosa nasalDoenças do narizBrazilA proposed new clinical staging system for patients with mucosal leishmaniasisinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/19037/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALLessa Hélio H A a proposed new clinical... .pdfLessa Hélio H A a proposed new clinical... 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| dc.title.pt_BR.fl_str_mv |
A proposed new clinical staging system for patients with mucosal leishmaniasis |
| title |
A proposed new clinical staging system for patients with mucosal leishmaniasis |
| spellingShingle |
A proposed new clinical staging system for patients with mucosal leishmaniasis Lessa, Hélio Andrade Leishmaniose Leishmaniose mucosa Estágio da doença Mucosa nasal Doenças do nariz Brasil Leishmaniasis Mucosal leishmaniasis Disease stage Nasal mucosa Nose diseases Brazil Leishmaniose Mucosa nasal Doenças do nariz Brazil |
| title_short |
A proposed new clinical staging system for patients with mucosal leishmaniasis |
| title_full |
A proposed new clinical staging system for patients with mucosal leishmaniasis |
| title_fullStr |
A proposed new clinical staging system for patients with mucosal leishmaniasis |
| title_full_unstemmed |
A proposed new clinical staging system for patients with mucosal leishmaniasis |
| title_sort |
A proposed new clinical staging system for patients with mucosal leishmaniasis |
| author |
Lessa, Hélio Andrade |
| author_facet |
Lessa, Hélio Andrade Lessa, Marcus Miranda Guimarães, Luiz Henrique Santos Lima, Clara Mônica Figueiredo de Arruda, Sérgio Marcos Machado, Paulo Roberto Lima Carvalho Filho, Edgar Marcelino |
| author_role |
author |
| author2 |
Lessa, Marcus Miranda Guimarães, Luiz Henrique Santos Lima, Clara Mônica Figueiredo de Arruda, Sérgio Marcos Machado, Paulo Roberto Lima Carvalho Filho, Edgar Marcelino |
| author2_role |
author author author author author author |
| dc.contributor.author.fl_str_mv |
Lessa, Hélio Andrade Lessa, Marcus Miranda Guimarães, Luiz Henrique Santos Lima, Clara Mônica Figueiredo de Arruda, Sérgio Marcos Machado, Paulo Roberto Lima Carvalho Filho, Edgar Marcelino |
| dc.subject.other.pt_BR.fl_str_mv |
Leishmaniose Leishmaniose mucosa Estágio da doença Mucosa nasal Doenças do nariz Brasil |
| topic |
Leishmaniose Leishmaniose mucosa Estágio da doença Mucosa nasal Doenças do nariz Brasil Leishmaniasis Mucosal leishmaniasis Disease stage Nasal mucosa Nose diseases Brazil Leishmaniose Mucosa nasal Doenças do nariz Brazil |
| dc.subject.en.pt_BR.fl_str_mv |
Leishmaniasis Mucosal leishmaniasis Disease stage Nasal mucosa Nose diseases Brazil |
| dc.subject.decs.pt_BR.fl_str_mv |
Leishmaniose Mucosa nasal Doenças do nariz Brazil |
| description |
Arruda, Sérgio Marcos “Documento produzido em parceria ou por autor vinculado à Fiocruz, mas não consta à informação no documento”. |
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2012 |
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2012 |
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2017-05-29T18:16:55Z |
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2017-05-29T18:16:55Z |
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info:eu-repo/semantics/publishedVersion |
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LESSA, H. A. et al. A proposed new clinical staging system for patients with mucosal leishmaniasis. Transactions of The Royal Society of Tropical Medicine and Hygiene, v. 106, n. 6, p. 376–381, 2012. |
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https://www.arca.fiocruz.br/handle/icict/19037 |
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0035-9203 |
| dc.identifier.doi.none.fl_str_mv |
10.1016/j.trstmh.2012.03.007 |
| identifier_str_mv |
LESSA, H. A. et al. A proposed new clinical staging system for patients with mucosal leishmaniasis. Transactions of The Royal Society of Tropical Medicine and Hygiene, v. 106, n. 6, p. 376–381, 2012. 0035-9203 10.1016/j.trstmh.2012.03.007 |
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Oxfor University Press |
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Oxfor University Press |
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