First detection of human T-lymphotropic virus in blood donors in Benin shows that testing is required to improve blood safety

Detalhes bibliográficos
Autor(a) principal: Amoussa, Adjile Edjide Roukiyath
Data de Publicação: 2018
Outros Autores: Kashima, Simone, Djobessi, Didier, Barreto, Fernanda Khouri, Davou, Denise, Bigot, Andre, Anani, Ludovic, Lourenco, Jose, Giovanetti, Marta, Sabino, Ester, Rahimy, Mohamed Cherif, Alcantara, Luiz Carlos Júnior
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/28844
Resumo: Brazilian Research councils: (CNPq-140152/2014-8; Conselho Nacional de Desenvolvimento Cientíıfico e Tecnológico. This is my PhD fellowship grant which is the result of collaboration between Brazil and Africa), (FAPESP-2013/08135-2; Fundação de Amparo a Pesquisa do Estado de São Paulo), (FINEP-1387/10; Ministério da Ciencia, Technologia, Inovações e Comunicações-Financiadora de Estudo e Projetos (Empresa Brasileira de inovação e Pesquisas), and the Centre de Prise en Charge Medicale Integree du Nourrisson et de la Femme Enceinte atteints de Drépanocytose (CPMINFED), the national instititute of sickle cell disease, the Ministry of Health and the Ministry of hight Education, Benin, Afrique and Agence National de Transfusion Sanguine (ANTS), the Ministry of Health and the Ministry of hight Education, Benin, Afrique.
id CRUZ_98b0d4b3f8eca27bb6015988b9015809
oai_identifier_str oai:www.arca.fiocruz.br:icict/28844
network_acronym_str CRUZ
network_name_str Repositório Institucional da FIOCRUZ (ARCA)
repository_id_str 2135
spelling Amoussa, Adjile Edjide RoukiyathKashima, SimoneDjobessi, DidierBarreto, Fernanda KhouriDavou, DeniseBigot, AndreAnani, LudovicLourenco, JoseGiovanetti, MartaSabino, EsterRahimy, Mohamed CherifAlcantara, Luiz Carlos Júnior2018-09-18T12:10:17Z2018-09-18T12:10:17Z2018AMOUSSA, A. E. R. et al. First detection of human T-lymphotropic virus in blood donors in Benin shows that testing is required to improve blood safety. ISBT Science Series, p. 1–6, 2018.1751-2816https://www.arca.fiocruz.br/handle/icict/28844Brazilian Research councils: (CNPq-140152/2014-8; Conselho Nacional de Desenvolvimento Cientíıfico e Tecnológico. This is my PhD fellowship grant which is the result of collaboration between Brazil and Africa), (FAPESP-2013/08135-2; Fundação de Amparo a Pesquisa do Estado de São Paulo), (FINEP-1387/10; Ministério da Ciencia, Technologia, Inovações e Comunicações-Financiadora de Estudo e Projetos (Empresa Brasileira de inovação e Pesquisas), and the Centre de Prise en Charge Medicale Integree du Nourrisson et de la Femme Enceinte atteints de Drépanocytose (CPMINFED), the national instititute of sickle cell disease, the Ministry of Health and the Ministry of hight Education, Benin, Afrique and Agence National de Transfusion Sanguine (ANTS), the Ministry of Health and the Ministry of hight Education, Benin, Afrique.Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, BrasilHemocentro de Ribeirão Preto. Ribeirão Preto, SP, BrasilService d’Immunologie Banque de Sang. Cotonou, BeninFundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, BrasilAgence Nationale pour la Transfusion Sanguine. Cotonou, BeninService d’Immunologie Banque de Sang. Cotonou, BeninAgence Nationale pour la Transfusion Sanguine. Cotonou, BeninUniversity of Oxford. Oxford, UKFundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, BrasilUniversity of São Paulo. São Paulo, BrasilCentre de Prise en Charge M edicale Int egr ee du Nourrisson et de la Femme Enceinte atteints de Drépanocytose. Cotonou, BeninFundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, BrasilIntroduction Human T-lymphotropic virus (HTLV) is a blood-borne infection that can be transmitted via blood transfusion. Knowing that blood safety can improve blood transfusion to prevent dissemination of viral infections in medical facilities, there is no routine pre-transfusion screening for HTLV in all blood banks in the Republic of Benin. This study aims to estimate the prevalence of HTLV infection in blood donors and describes the characteristics of positive donors. Methods A HTLV prevalence study was carried out by screening 2,035 samples by an enzyme-linked immunoassay obtained from six blood banks located throughout the Republic of Benin. The PCR method was used to confirm and type all the ELISA reactive samples. Results and discussion Twelve subjects, all volunteer blood donors, were found with positive serology confirmed by a specific HTLV type 1 PCR assay, representing an overall seroprevalence of 0 59%. Furthermore, seven subjects were indeterminate for anti-HTLV-1/2 antibody and only one sample was confirmed positive for HTLV type 1 in a PCR reaction. These are the first cases of HTLV detection among blood donors in Benin Republic, whose blood was already transfused to recipients. This result emphasizes that HTLV needs to be considered as a Public Health issue in the Republic of Benin. Conclusion This study reports positive result of HTLV infection among blood donors in the blood banks of Benin Republic in West Africa and highlights the inclusion of screening tests and strategies to reduce its transmission.engWileyDoadores de sangueHTLVPrevalência de HTLVTeste de HTLVBlood donorsHTLVHTLV prevalenceHTLV testingFirst detection of human T-lymphotropic virus in blood donors in Benin shows that testing is required to improve blood safetyinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/28844/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALAmoussa AE First detection of human....pdfAmoussa AE First detection of human....pdfapplication/pdf133202https://www.arca.fiocruz.br/bitstream/icict/28844/2/Amoussa%20AE%20First%20detection%20of%20human....pdfed776ce0e231480498e40d01f24ad232MD52TEXTAmoussa AE First detection of human....pdf.txtAmoussa AE First detection of human....pdf.txtExtracted texttext/plain24090https://www.arca.fiocruz.br/bitstream/icict/28844/3/Amoussa%20AE%20First%20detection%20of%20human....pdf.txt4525d05e3c38a9f533c9b3555cb363efMD53icict/288442023-03-15 14:33:14.723oai:www.arca.fiocruz.br:icict/28844Q0VTU8ODTyBOw4NPIEVYQ0xVU0lWQSBERSBESVJFSVRPUyBBVVRPUkFJUwoKQW8gYWNlaXRhciBvcyBURVJNT1MgZSBDT05EScOHw5VFUyBkZXN0YSBDRVNTw4NPLCBvIEFVVE9SIGUvb3UgVElUVUxBUiBkZSBkaXJlaXRvcwphdXRvcmFpcyBzb2JyZSBhIE9CUkEgZGUgcXVlIHRyYXRhIGVzdGUgZG9jdW1lbnRvOgoKKDEpIENFREUgZSBUUkFOU0ZFUkUsIHRvdGFsIGUgZ3JhdHVpdGFtZW50ZSwgw6AgRklPQ1JVWiAtIEZVTkRBw4fDg08gT1NXQUxETyBDUlVaLCBlbQpjYXLDoXRlciBwZXJtYW5lbnRlLCBpcnJldm9nw6F2ZWwgZSBOw4NPIEVYQ0xVU0lWTywgdG9kb3Mgb3MgZGlyZWl0b3MgcGF0cmltb25pYWlzIE7Dg08KQ09NRVJDSUFJUyBkZSB1dGlsaXphw6fDo28gZGEgT0JSQSBhcnTDrXN0aWNhIGUvb3UgY2llbnTDrWZpY2EgaW5kaWNhZGEgYWNpbWEsIGluY2x1c2l2ZSBvcyBkaXJlaXRvcwpkZSB2b3ogZSBpbWFnZW0gdmluY3VsYWRvcyDDoCBPQlJBLCBkdXJhbnRlIHRvZG8gbyBwcmF6byBkZSBkdXJhw6fDo28gZG9zIGRpcmVpdG9zIGF1dG9yYWlzLCBlbQpxdWFscXVlciBpZGlvbWEgZSBlbSB0b2RvcyBvcyBwYcOtc2VzOwoKKDIpIEFDRUlUQSBxdWUgYSBjZXNzw6NvIHRvdGFsIG7Do28gZXhjbHVzaXZhLCBwZXJtYW5lbnRlIGUgaXJyZXZvZ8OhdmVsIGRvcyBkaXJlaXRvcyBhdXRvcmFpcwpwYXRyaW1vbmlhaXMgbsOjbyBjb21lcmNpYWlzIGRlIHV0aWxpemHDp8OjbyBkZSBxdWUgdHJhdGEgZXN0ZSBkb2N1bWVudG8gaW5jbHVpLCBleGVtcGxpZmljYXRpdmFtZW50ZSwKb3MgZGlyZWl0b3MgZGUgZGlzcG9uaWJpbGl6YcOnw6NvIGUgY29tdW5pY2HDp8OjbyBww7pibGljYSBkYSBPQlJBLCBlbSBxdWFscXVlciBtZWlvIG91IHZlw61jdWxvLAppbmNsdXNpdmUgZW0gUmVwb3NpdMOzcmlvcyBEaWdpdGFpcywgYmVtIGNvbW8gb3MgZGlyZWl0b3MgZGUgcmVwcm9kdcOnw6NvLCBleGliacOnw6NvLCBleGVjdcOnw6NvLApkZWNsYW1hw6fDo28sIHJlY2l0YcOnw6NvLCBleHBvc2nDp8OjbywgYXJxdWl2YW1lbnRvLCBpbmNsdXPDo28gZW0gYmFuY28gZGUgZGFkb3MsIHByZXNlcnZhw6fDo28sIGRpZnVzw6NvLApkaXN0cmlidWnDp8OjbywgZGl2dWxnYcOnw6NvLCBlbXByw6lzdGltbywgdHJhZHXDp8OjbywgZHVibGFnZW0sIGxlZ2VuZGFnZW0sIGluY2x1c8OjbyBlbSBub3ZhcyBvYnJhcyBvdQpjb2xldMOibmVhcywgcmV1dGlsaXphw6fDo28sIGVkacOnw6NvLCBwcm9kdcOnw6NvIGRlIG1hdGVyaWFsIGRpZMOhdGljbyBlIGN1cnNvcyBvdSBxdWFscXVlciBmb3JtYSBkZQp1dGlsaXphw6fDo28gbsOjbyBjb21lcmNpYWw7CgooMykgUkVDT05IRUNFIHF1ZSBhIGNlc3PDo28gYXF1aSBlc3BlY2lmaWNhZGEgY29uY2VkZSDDoCBGSU9DUlVaIC0gRlVOREHDh8ODTyBPU1dBTERPCkNSVVogbyBkaXJlaXRvIGRlIGF1dG9yaXphciBxdWFscXVlciBwZXNzb2Eg4oCTIGbDrXNpY2Egb3UganVyw61kaWNhLCBww7pibGljYSBvdSBwcml2YWRhLCBuYWNpb25hbCBvdQplc3RyYW5nZWlyYSDigJMgYSBhY2Vzc2FyIGUgdXRpbGl6YXIgYW1wbGFtZW50ZSBhIE9CUkEsIHNlbSBleGNsdXNpdmlkYWRlLCBwYXJhIHF1YWlzcXVlcgpmaW5hbGlkYWRlcyBuw6NvIGNvbWVyY2lhaXM7CgooNCkgREVDTEFSQSBxdWUgYSBvYnJhIMOpIGNyaWHDp8OjbyBvcmlnaW5hbCBlIHF1ZSDDqSBvIHRpdHVsYXIgZG9zIGRpcmVpdG9zIGFxdWkgY2VkaWRvcyBlIGF1dG9yaXphZG9zLApyZXNwb25zYWJpbGl6YW5kby1zZSBpbnRlZ3JhbG1lbnRlIHBlbG8gY29udGXDumRvIGUgb3V0cm9zIGVsZW1lbnRvcyBxdWUgZmF6ZW0gcGFydGUgZGEgT0JSQSwKaW5jbHVzaXZlIG9zIGRpcmVpdG9zIGRlIHZveiBlIGltYWdlbSB2aW5jdWxhZG9zIMOgIE9CUkEsIG9icmlnYW5kby1zZSBhIGluZGVuaXphciB0ZXJjZWlyb3MgcG9yCmRhbm9zLCBiZW0gY29tbyBpbmRlbml6YXIgZSByZXNzYXJjaXIgYSBGSU9DUlVaIC0gRlVOREHDh8ODTyBPU1dBTERPIENSVVogZGUKZXZlbnR1YWlzIGRlc3Blc2FzIHF1ZSB2aWVyZW0gYSBzdXBvcnRhciwgZW0gcmF6w6NvIGRlIHF1YWxxdWVyIG9mZW5zYSBhIGRpcmVpdG9zIGF1dG9yYWlzIG91CmRpcmVpdG9zIGRlIHZveiBvdSBpbWFnZW0sIHByaW5jaXBhbG1lbnRlIG5vIHF1ZSBkaXogcmVzcGVpdG8gYSBwbMOhZ2lvIGUgdmlvbGHDp8O1ZXMgZGUgZGlyZWl0b3M7CgooNSkgQUZJUk1BIHF1ZSBjb25oZWNlIGEgUG9sw610aWNhIEluc3RpdHVjaW9uYWwgZGUgQWNlc3NvIEFiZXJ0byBkYSBGSU9DUlVaIC0gRlVOREHDh8ODTwpPU1dBTERPIENSVVogZSBhcyBkaXJldHJpemVzIHBhcmEgbyBmdW5jaW9uYW1lbnRvIGRvIHJlcG9zaXTDs3JpbyBpbnN0aXR1Y2lvbmFsIEFSQ0EuCgpBIFBvbMOtdGljYSBJbnN0aXR1Y2lvbmFsIGRlIEFjZXNzbyBBYmVydG8gZGEgRklPQ1JVWiAtIEZVTkRBw4fDg08gT1NXQUxETyBDUlVaIHJlc2VydmEKZXhjbHVzaXZhbWVudGUgYW8gQVVUT1Igb3MgZGlyZWl0b3MgbW9yYWlzIGUgb3MgdXNvcyBjb21lcmNpYWlzIHNvYnJlIGFzIG9icmFzIGRlIHN1YSBhdXRvcmlhCmUvb3UgdGl0dWxhcmlkYWRlLCBzZW5kbyBvcyB0ZXJjZWlyb3MgdXN1w6FyaW9zIHJlc3BvbnPDoXZlaXMgcGVsYSBhdHJpYnVpw6fDo28gZGUgYXV0b3JpYSBlIG1hbnV0ZW7Dp8OjbwpkYSBpbnRlZ3JpZGFkZSBkYSBPQlJBIGVtIHF1YWxxdWVyIHV0aWxpemHDp8Ojby4KCkEgUG9sw610aWNhIEluc3RpdHVjaW9uYWwgZGUgQWNlc3NvIEFiZXJ0byBkYSBGSU9DUlVaIC0gRlVOREHDh8ODTyBPU1dBTERPIENSVVoKcmVzcGVpdGEgb3MgY29udHJhdG9zIGUgYWNvcmRvcyBwcmVleGlzdGVudGVzIGRvcyBBdXRvcmVzIGNvbSB0ZXJjZWlyb3MsIGNhYmVuZG8gYW9zIEF1dG9yZXMKaW5mb3JtYXIgw6AgSW5zdGl0dWnDp8OjbyBhcyBjb25kacOnw7VlcyBlIG91dHJhcyByZXN0cmnDp8O1ZXMgaW1wb3N0YXMgcG9yIGVzdGVzIGluc3RydW1lbnRvcy4KRepositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352023-03-15T17:33:14Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.pt_BR.fl_str_mv First detection of human T-lymphotropic virus in blood donors in Benin shows that testing is required to improve blood safety
title First detection of human T-lymphotropic virus in blood donors in Benin shows that testing is required to improve blood safety
spellingShingle First detection of human T-lymphotropic virus in blood donors in Benin shows that testing is required to improve blood safety
Amoussa, Adjile Edjide Roukiyath
Doadores de sangue
HTLV
Prevalência de HTLV
Teste de HTLV
Blood donors
HTLV
HTLV prevalence
HTLV testing
title_short First detection of human T-lymphotropic virus in blood donors in Benin shows that testing is required to improve blood safety
title_full First detection of human T-lymphotropic virus in blood donors in Benin shows that testing is required to improve blood safety
title_fullStr First detection of human T-lymphotropic virus in blood donors in Benin shows that testing is required to improve blood safety
title_full_unstemmed First detection of human T-lymphotropic virus in blood donors in Benin shows that testing is required to improve blood safety
title_sort First detection of human T-lymphotropic virus in blood donors in Benin shows that testing is required to improve blood safety
author Amoussa, Adjile Edjide Roukiyath
author_facet Amoussa, Adjile Edjide Roukiyath
Kashima, Simone
Djobessi, Didier
Barreto, Fernanda Khouri
Davou, Denise
Bigot, Andre
Anani, Ludovic
Lourenco, Jose
Giovanetti, Marta
Sabino, Ester
Rahimy, Mohamed Cherif
Alcantara, Luiz Carlos Júnior
author_role author
author2 Kashima, Simone
Djobessi, Didier
Barreto, Fernanda Khouri
Davou, Denise
Bigot, Andre
Anani, Ludovic
Lourenco, Jose
Giovanetti, Marta
Sabino, Ester
Rahimy, Mohamed Cherif
Alcantara, Luiz Carlos Júnior
author2_role author
author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Amoussa, Adjile Edjide Roukiyath
Kashima, Simone
Djobessi, Didier
Barreto, Fernanda Khouri
Davou, Denise
Bigot, Andre
Anani, Ludovic
Lourenco, Jose
Giovanetti, Marta
Sabino, Ester
Rahimy, Mohamed Cherif
Alcantara, Luiz Carlos Júnior
dc.subject.other.pt_BR.fl_str_mv Doadores de sangue
HTLV
Prevalência de HTLV
Teste de HTLV
topic Doadores de sangue
HTLV
Prevalência de HTLV
Teste de HTLV
Blood donors
HTLV
HTLV prevalence
HTLV testing
dc.subject.en.pt_BR.fl_str_mv Blood donors
HTLV
HTLV prevalence
HTLV testing
description Brazilian Research councils: (CNPq-140152/2014-8; Conselho Nacional de Desenvolvimento Cientíıfico e Tecnológico. This is my PhD fellowship grant which is the result of collaboration between Brazil and Africa), (FAPESP-2013/08135-2; Fundação de Amparo a Pesquisa do Estado de São Paulo), (FINEP-1387/10; Ministério da Ciencia, Technologia, Inovações e Comunicações-Financiadora de Estudo e Projetos (Empresa Brasileira de inovação e Pesquisas), and the Centre de Prise en Charge Medicale Integree du Nourrisson et de la Femme Enceinte atteints de Drépanocytose (CPMINFED), the national instititute of sickle cell disease, the Ministry of Health and the Ministry of hight Education, Benin, Afrique and Agence National de Transfusion Sanguine (ANTS), the Ministry of Health and the Ministry of hight Education, Benin, Afrique.
publishDate 2018
dc.date.accessioned.fl_str_mv 2018-09-18T12:10:17Z
dc.date.available.fl_str_mv 2018-09-18T12:10:17Z
dc.date.issued.fl_str_mv 2018
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv AMOUSSA, A. E. R. et al. First detection of human T-lymphotropic virus in blood donors in Benin shows that testing is required to improve blood safety. ISBT Science Series, p. 1–6, 2018.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/28844
dc.identifier.issn.pt_BR.fl_str_mv 1751-2816
identifier_str_mv AMOUSSA, A. E. R. et al. First detection of human T-lymphotropic virus in blood donors in Benin shows that testing is required to improve blood safety. ISBT Science Series, p. 1–6, 2018.
1751-2816
url https://www.arca.fiocruz.br/handle/icict/28844
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Wiley
publisher.none.fl_str_mv Wiley
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
bitstream.url.fl_str_mv https://www.arca.fiocruz.br/bitstream/icict/28844/1/license.txt
https://www.arca.fiocruz.br/bitstream/icict/28844/2/Amoussa%20AE%20First%20detection%20of%20human....pdf
https://www.arca.fiocruz.br/bitstream/icict/28844/3/Amoussa%20AE%20First%20detection%20of%20human....pdf.txt
bitstream.checksum.fl_str_mv 5a560609d32a3863062d77ff32785d58
ed776ce0e231480498e40d01f24ad232
4525d05e3c38a9f533c9b3555cb363ef
bitstream.checksumAlgorithm.fl_str_mv MD5
MD5
MD5
repository.name.fl_str_mv Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)
repository.mail.fl_str_mv repositorio.arca@fiocruz.br
_version_ 1798324921233833984

Registros relacionados