Development and validation of the personalized sexual health promotion (SexPro) HIV risk prediction model for men who have sex with men in the United States

Detalhes bibliográficos
Autor(a) principal: Scott, Hyman
Data de Publicação: 2019
Outros Autores: Vittinghoff, Eric, Irvin, Risha, Liu, Albert, Nelson, LaRon, Rio, Carlos del, Magnus, Manya, Mannheimer, Sharon, Fields, Sheldon, Tieu, Hong van, Kuo, Irene, Shoptaw, Steve, Grinsztejn, Beatriz, Sanchez, Jorge, Wakefield, Steven, Fuchs, Jonathan D., Wheeler, Darrell, Mayer, Kenneth H., Koblin, Beryl A., Buchbinder, Susan
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/35491
Resumo: 2020-09-11
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spelling Scott, HymanVittinghoff, EricIrvin, RishaLiu, AlbertNelson, LaRonRio, Carlos delMagnus, ManyaMannheimer, SharonFields, SheldonTieu, Hong vanKuo, IreneShoptaw, SteveGrinsztejn, BeatrizSanchez, JorgeWakefield, StevenFuchs, Jonathan D.Wheeler, DarrellMayer, Kenneth H.Koblin, Beryl A.Buchbinder, Susan2019-09-11T13:23:52Z2019-09-11T13:23:52Z2019SCOTT, Hyman et al. Development and validation of the personalized sexual health promotion (SexPro) HIV risk prediction model for men who have sex with men in the United States. AIDS and Behavior, p. 1-10, 27 July 2019.1090-7165https://www.arca.fiocruz.br/handle/icict/3549110.1007/s10461-019-02616-31573-3254engSpringerDevelopment and validation of the personalized sexual health promotion (SexPro) HIV risk prediction model for men who have sex with men in the United Statesinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article2020-09-11San Francisco Department of Public Health. Bridge HIV. San Francisco, CA, USA.University of California. San Francisco, CA, USA.Johns Hopkins School of Medicine. Baltimore, MD, USA.San Francisco Department of Public Health. Bridge HIV. San Francisco, CA, USA.Yale School of Nursing. New Haven, CT, USA.Emory University. Atlanta, GA, USA.George Washington University. Washington, DC, USA.Columbia University. New York, NY, USA.New York Institute of Technology. Old Westbury, NY, USA.New York Blood Center. New York, NY, USA.George Washington University. Washington, DC, USA.University of California, Los Angeles, CA, USAFundação Oswaldo Cruz. Instituto de Pesquisa Clinica Evandro Chagas. Rio de Janeiro, RJ, Brasil.Asociacion Civil Impacta Salud y Educacion. Lima, Peru.Fred Hutchinson Cancer Research Center. Seattle, WA, USA.San Francisco Department of Public Health. Center for Learning Innovation. San Francisco, CA, USA.University at Albany. Albany, NY, USA.Fenway Health. Boston, MA, USA.New York Blood Center. New York, NY, USA.San Francisco Department of Public Health. Bridge HIV. San Francisco, CA, USA.Accurate HIV risk assessment among men who have sex with men (MSM) is important to help providers assess risk, and target HIV prevention interventions. We sought to develop an evidence-based HIV risk assessment tool for US MSM that is inclusive of Black MSM. Data from four large longitudinal cohorts of MSM were used to develop (EXPLORE), and validate (VAX004, HPTN061, and HVTN505). These data included visits in which participants self-reported HIV risk behavior and underwent HIV testing. We developed a pooled logistic model for incident HIV infection based on self-reported risk behaviors during the 6 months before each study visit. A total of 4069 MSM were used for the development cohort, and 8047 MSM in the three validation cohorts through 2013. The final model includes age (< 35, ≥ 35); Black race and Latino ethnicity; numbers of HIV-negative anal sex partners; number of insertive or receptive anal intercourse episodes; having 1 HIV-negative partner only; self-reported substance use; and bacterial sexually transmitted infection diagnosis. The model showed good discrimination in internal validation (C-statistic = 79.5). The external validation cohorts also showed good discrimination, with C-statistics of 73.1, 71.0, 71.9 in VAX004, HPTN061, and HVTN505 respectively, and acceptable calibration. We developed and validated an HIV risk assessment tool for MSM, which showed good predictive ability, including among the largest cohort of HIV-uninfected Black MSM in the US. This tool is available online (mysexpro.org) and can be used by providers to support targeting of HIV prevention interventions such as pre-exposure prophylaxis for MSM.HIV risk assessmentMSMHIV preventioninfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-83099https://www.arca.fiocruz.br/bitstream/icict/35491/1/license.txt586c046dcfeef936e32f0323bb9a47c0MD51ORIGINALDevelopment and Validation_Beatriz_Grinsztejn_INI_Lapclin-AIDS_2019.pdfDevelopment and Validation_Beatriz_Grinsztejn_INI_Lapclin-AIDS_2019.pdfapplication/pdf1055903https://www.arca.fiocruz.br/bitstream/icict/35491/2/Development%20and%20Validation_Beatriz_Grinsztejn_INI_Lapclin-AIDS_2019.pdf3aeb9c8434b734fcd3c70f23df99f11eMD52TEXTDevelopment and Validation_Beatriz_Grinsztejn_INI_Lapclin-AIDS_2019.pdf.txtDevelopment and 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dc.title.pt_BR.fl_str_mv Development and validation of the personalized sexual health promotion (SexPro) HIV risk prediction model for men who have sex with men in the United States
title Development and validation of the personalized sexual health promotion (SexPro) HIV risk prediction model for men who have sex with men in the United States
spellingShingle Development and validation of the personalized sexual health promotion (SexPro) HIV risk prediction model for men who have sex with men in the United States
Scott, Hyman
HIV risk assessment
MSM
HIV prevention
title_short Development and validation of the personalized sexual health promotion (SexPro) HIV risk prediction model for men who have sex with men in the United States
title_full Development and validation of the personalized sexual health promotion (SexPro) HIV risk prediction model for men who have sex with men in the United States
title_fullStr Development and validation of the personalized sexual health promotion (SexPro) HIV risk prediction model for men who have sex with men in the United States
title_full_unstemmed Development and validation of the personalized sexual health promotion (SexPro) HIV risk prediction model for men who have sex with men in the United States
title_sort Development and validation of the personalized sexual health promotion (SexPro) HIV risk prediction model for men who have sex with men in the United States
author Scott, Hyman
author_facet Scott, Hyman
Vittinghoff, Eric
Irvin, Risha
Liu, Albert
Nelson, LaRon
Rio, Carlos del
Magnus, Manya
Mannheimer, Sharon
Fields, Sheldon
Tieu, Hong van
Kuo, Irene
Shoptaw, Steve
Grinsztejn, Beatriz
Sanchez, Jorge
Wakefield, Steven
Fuchs, Jonathan D.
Wheeler, Darrell
Mayer, Kenneth H.
Koblin, Beryl A.
Buchbinder, Susan
author_role author
author2 Vittinghoff, Eric
Irvin, Risha
Liu, Albert
Nelson, LaRon
Rio, Carlos del
Magnus, Manya
Mannheimer, Sharon
Fields, Sheldon
Tieu, Hong van
Kuo, Irene
Shoptaw, Steve
Grinsztejn, Beatriz
Sanchez, Jorge
Wakefield, Steven
Fuchs, Jonathan D.
Wheeler, Darrell
Mayer, Kenneth H.
Koblin, Beryl A.
Buchbinder, Susan
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Scott, Hyman
Vittinghoff, Eric
Irvin, Risha
Liu, Albert
Nelson, LaRon
Rio, Carlos del
Magnus, Manya
Mannheimer, Sharon
Fields, Sheldon
Tieu, Hong van
Kuo, Irene
Shoptaw, Steve
Grinsztejn, Beatriz
Sanchez, Jorge
Wakefield, Steven
Fuchs, Jonathan D.
Wheeler, Darrell
Mayer, Kenneth H.
Koblin, Beryl A.
Buchbinder, Susan
dc.subject.en.pt_BR.fl_str_mv HIV risk assessment
MSM
HIV prevention
topic HIV risk assessment
MSM
HIV prevention
description 2020-09-11
publishDate 2019
dc.date.accessioned.fl_str_mv 2019-09-11T13:23:52Z
dc.date.available.fl_str_mv 2019-09-11T13:23:52Z
dc.date.issued.fl_str_mv 2019
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv SCOTT, Hyman et al. Development and validation of the personalized sexual health promotion (SexPro) HIV risk prediction model for men who have sex with men in the United States. AIDS and Behavior, p. 1-10, 27 July 2019.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/35491
dc.identifier.issn.pt_BR.fl_str_mv 1090-7165
dc.identifier.doi.none.fl_str_mv 10.1007/s10461-019-02616-3
dc.identifier.eissn.none.fl_str_mv 1573-3254
identifier_str_mv SCOTT, Hyman et al. Development and validation of the personalized sexual health promotion (SexPro) HIV risk prediction model for men who have sex with men in the United States. AIDS and Behavior, p. 1-10, 27 July 2019.
1090-7165
10.1007/s10461-019-02616-3
1573-3254
url https://www.arca.fiocruz.br/handle/icict/35491
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Springer
publisher.none.fl_str_mv Springer
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
bitstream.url.fl_str_mv https://www.arca.fiocruz.br/bitstream/icict/35491/1/license.txt
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